Gonadotropin-releasing hormone agonist protocols for pituitary suppression in assisted reproduction.

Background: Gonadotropin-releasing hormone agonists (GnRHa) are commonly used in assisted reproduction technology (ART) cycles to prevent a luteinising hormone (LH) surge during controlled ovarian hyperstimulation (COH) prior to planned oocyte retrieval, thus optimising the chances of live birth. We compared the benefits and risks of the different GnRHa protocols used.

Objectives: To evaluate the effectiveness and safety of different GnRHa protocols used as adjuncts to COH in women undergoing ART.

Establishment and application of a high-performance liquid chromatography-mass spectrometry method for analysis of 15 bisphenols and halogenated phenols in tea.

Using high-performance liquid chromatography-mass spectrometry, fifteen bisphenols and halogenated phenols were simultaneously analyzed in tea for the first time in China. Response surface methodology was used to optimize sample preparation conditions based on QuEChERS. Finally, the limits of detection and the limits of quantification were 0.

Effect of hot isostatic pressing on microstructure and properties of cooled hot dip aluminum coating in magnetic field.

The effect of hot isostatic pressing (HIP) on the microstructure and properties of hot dip aluminum coating cooled in a magnetic field was investigated in this study. In order to improve the microstructure and properties of magnetic dip aluminum coating, hot isostatic pressing technology was used for post-treatment. Initially, a traditional aluminum-impregnated coating was prepared on the surface of titanium alloy TA15, an alternating electromagnetic field was applied during the forming and solidification process of the coating.

Does Secondary Mechanical Manipulation of Lipoaspirate Enhance the Vasculogenic Potential of Fat Grafts? A Systematic Review.

Background: Fat grafting is a highly versatile option in the reconstructive armamentarium but with unpredictable retention rates and outcomes. The primary outcome of this systematic review was to assess whether secondary mechanically processed lipoaspirate favorably enhances the vasculogenic potential of fat grafts when compared to unprocessed lipoaspirate or fat grafts prepared using centrifugation alone. The secondary outcome was to assess the evidence around graft retention and improved outcomes when comparing the aforementioned groups.

Development of a Non-Target Screening and Quantitative Analysis Strategy Based on UPLC-Q-TOF/MS and UPLC-QQQ/MS to Improve the Quality Control of Wuling Capsule.

Herbal medicine has been widely valued because of its remarkable efficacy and minimal side effects. The quantitative analysis of herbal medicines is essential to ensure their safety and efficacy. The simultaneous detection of multiple quality markers (Q-markers) has emerged as an important approach and trend in herbal medicine quality control.

The screening method for 39 phytotoxins and mycotoxins in blood and urine with liquid chromatography-high resolution mass spectrometry.

Background: Poisonings caused by plant toxins and mycotoxins occur frequently, which do great harm to human health and social public health safety. When a poisoning incident occurs, biological samples are commonly be used to conduct the detection of toxic substances and their metabolites for targeted clinical treatment and incident analysis.

Objective: To establish an efficient and accurate analysis method of 39 phytotoxins and mycotoxins in blood and urine by high performance liquid chromatography quadrupole tandem orbitrap mass spectrometry (HPLC-Orbitrap MS).

Incidence and predictors of posttraumatic epilepsy and cognitive impairment in patients with traumatic brain injury: A retrospective cohort study in Malaysia.

Objective: Posttraumatic epilepsy (PTE) significantly impacts morbidity and mortality, yet local PTE data remain scarce. In addition, there is a lack of evidence on cognitive comorbidity in individuals with PTE in the literature. We sought to identify potential PTE predictors and evaluate cognitive comorbidity in patients with PTE.

Chemical derivatization strategies for enhancing the HPLC analytical performance of natural active triterpenoids.

Triterpenoids widely exist in nature, displaying a variety of pharmacological activities. Determining triterpenoids in different matrices, especially in biological samples holds great significance. High-performance liquid chromatography (HPLC) has become the predominant method for triterpenoids analysis due to its exceptional analytical performance.

Deep learning-based prediction of in-hospital mortality for sepsis.

As a serious blood infection disease, sepsis is characterized by a high mortality risk and many complications. Accurate assessment of mortality risk of patients with sepsis can help physicians in Intensive Care Unit make optimal clinical decisions, which in turn can effectively save patients' lives. However, most of the current clinical models used for assessing mortality risk in sepsis patients are based on conventional indicators.

The association between perchlorate in drinking water and height and weight of children and adolescents in Southwest China: a retrospective cross-sectional study.

Objective: To investigate the association between the concentration of perchlorate in drinking water and the height and weight of children and adolescents in Sichuan Province.

Methods: Perchlorate in the drinking water of 24 counties in Sichuan Province from 2021 to 2022 was detected and analyzed, 66 drinking water samples were collected, and the content of perchlorate in drinking water during the wet season and dry season was detected by ultra-high performance liquid chromatography in series. The linear mixed effect model was used to estimate the relationship between perchlorate in drinking water and the height and weight of 144,644 children and adolescents, and 33 pieces of local average wage data were used as confounding factors for quality control.

Cavernous Sinus MRI Findings in Inflammatory and Ischemic Oculomotor Cranial Nerve Palsies.

Background: The significance of asymmetric enhancement on cavernous sinus MRIs in the differential diagnosis of ischemic and inflammatory oculomotor cranial nerve (OCN) palsies remains controversial. This study explored the cavernous sinus MRI findings for cavernous sinus idiopathic inflammation (inflammation group), microvascular ischemic OCN palsy (ischemic group), and ocular myasthenia gravis (OMG group) patients.

Methods: A total of 66, 117, and 60 patients were included in the inflammation, ischemic, and OMG groups, respectively.

Prevalence and predictors of vitamin D deficiency among adults with epilepsy: A cross-sectional study.

Background: Vitamin D deficiency among adult people with epilepsy (PWE) is scarcely studied, despite its essential role in bone health and maintaining homeostasis. Several studies have studied the relationship between factors related to epilepsy and vitamin D metabolism. We aim to investigate this in our multi-ethnic society.

Correction: Undenatured type II collagen prevents and treats osteoarthritis and motor function degradation in T2DM patients and db/db mice.

Correction for 'Undenatured type II collagen prevents and treats osteoarthritis and motor function degradation in T2DM patients and db/db mice' by Fan Rui , , 2021, , 4373-4391, https://doi.org/10.1039/D0FO03011B.

Fibronectin matrix assembly and TGFβ1 presentation for chondrogenesis of patient derived pericytes for microtia repair.

Tissue engineered cartilage for external ear reconstruction of congenital deformities, such as microtia or resulting from trauma, remains a significant challenge for plastic and reconstructive surgeons. Current strategies involve harvesting autologous costal cartilage or expanding autologous chondrocytes ex vivo. However, these procedures often lead to donor site morbidity and a cell source with limited expansion capacity.

Effects of nitrogen application rate on the accumulation of C assimilates after flowering and water-nitrogen use efficiency of wheat under supplemental irrigation based on soil moisture.

This study aimed to explore nitrogen fertilizer management measures to synergistically improve wheat yields and water and nitrogen use efficiency under supplemental irrigation based on soil moisture in the Huang Huai winter wheat area. Wheat variety "Yannong 1212" was used as the test material. There were three nitrogen application levels, 150 kg·hm (N), 210 kg·hm (N), and 270 kg·hm (the conventional nitrogen application rate in the Huang Huai winter wheat area, N), with the relative soil water content of 0-40 cm of each treatment was supplemented to 70% at the jointing and flowering stages.

The role of Fintech in circular economy practices to improve sustainability performance: a two-staged SEM-ANN approach.

Coupling the practice-based view (PBV) of firms with dynamic capabilities theory (DCT), we assess the effect of Fintech adoption (FA) on organizational sustainability performance (SP) through circular economy practices (CEP). Additionally, this research examines the moderating roles of a firm's access to finance (AF) and absorptive capacity (AC) in the interplays between the constructs. Three hundred responses were collected from Bangladeshi manufacturing SMEs using a structured questionnaire.

Determination of 19 Fragrance Allergens in Paper Household Goods by Solid-Liquid Extraction-Dispersive Liquid-Liquid Microextraction-GC-MS.

Background: Fragrance allergens (FAs) refer to these volatile or semi-volatile fragrance compounds that can induce sensitization, and they are widely used in household goods.

Objective: In this work, a method combining solid-liquid extraction (SLE) and dispersive liquid-liquid microextraction (DLLME) with gas chromatography-mass spectrometry (GC-MS) has been developed and applied in the analysis of 19 FAs (including hydrocarbons, alcohols, aldehydes, esters, and phenols) in paper household goods.

Method: The samples (infant or personal paper hygiene products) were cut into small pieces and underwent SLE with methanol as solvent.

A study using LC-MS/MS-based metabolomics to investigate the effects of iron oxide nanoparticles on rat liver.

Iron oxide nanoparticles (IONPs) are widely used in food additives, but their metabolic mechanism in the body is still unclear. In this study, male Sprague-Dawley rats were orally administered with IONPs for 28 days to investigate the adverse effect and metabolic mechanism on liver by the combination of traditional toxicology technology and liquid chromatography tandem-mass spectrometry (LC-MS/MS)-based metabolomics. The results showed that IONPs could increase the concentration of blood glucose and the metabolites in the liver of the control and IONPs-treated group were significantly changed.

Insight on the microscopic binding mechanism of bisphenol compounds (BPs) with transthyretin (TTR) based on multi-spectroscopic methods and computational simulations.

Thyroid hormones are involved in numerous physiological processes as regulators of metabolism, regulating organ growth, and mental state. Bisphenol compounds (BPs) are recognized as chemicals that interfere with endocrine balance. Because BPs have a similar structure to thyroxine, they can compete for binding to thyroid protein and disrupt the normal physiological activity of the thyroid system.

Post-traumatic Stress Symptoms in Adolescents Exposed to the Earthquake in Lombok, Indonesia: Prevalence and Association With Maladaptive Trauma-Related Cognition and Resilience.

Natural disasters may physically and psychologically affect individuals and their surrounding community. This study determines the prevalence of post-traumatic stress (PTS) symptoms and its association with maladaptive trauma-related cognition and resilience among adolescents post-earthquake. Data were collected, in this cross-sectional study, during an intervention program post-earthquake held in a state high school located at Lombok, Indonesia.

A Practical Method for Determination of Nine Nucleosides in by UPLC/MS and Quantitative Analysis of Multicomponents Using Single Marker Method.

Nucleosides can be used as quality evaluation indicators of . In this work, a new ultra-performance liquid chromatography-tandem mass spectrometry (UPLC/MS) strategy for quantitative analysis of multiple components using a single marker (QAMS) was proposed to determine nine nucleosides (adenosine, cytidine, guanosine, inosine, uridine, 2'-deoxyadenosine, 2'-deoxycytidine, 2'-deoxyguanosine, and 2'-deoxyuridine) in . Guanosine was set as the internal reference substance, whose content in was determined using the conventional external standard method.

The Value of the Distal Radioulnar Joint Effusion in Diagnosing Triangular Fibrocartilage Complex Tears on Magnetic Resonance Imaging.

Background: A retrospective study was conducted to evaluate the role of distal radioulnar joint (DRUJ) effusion in aiding the diagnostic accuracy of central triangular fibrocartilage complex (TFCC) tears on non-contrast MRI.

Methods: 89 consecutive patients who had undergone wrist arthroscopy for ulna sided wrist pain in our unit were identified and their preoperative imaging reviewed. Two consultant musculoskeletal Radiologists independently reported the presence or absence of a DRUJ effusion and or a TFCC tear.