Aims: We aim to elucidate the association of baseline eGFR and incident heart failure on patients receiving intensive BP treatment.
Methods And Results: A post hoc analysis was conducted on the SPRINT database. Multivariab le Cox regression and interaction restricted cubic spline (RCS) analysis were performed to investigate the interaction between baseline eGFR and intensive BP control on heart failure prevention.
Comput Biol Med
January 2025
This paper presents AIScholar, an intelligent research cloud platform developed based on artificial intelligence analysis methods and the OpenFaaS serverless framework, designed for intelligent analysis of clinical medical data with high scalability. AIScholar simplifies the complex analysis process by encapsulating a wide range of medical data analytics methods into a series of customizable cloud tools that emphasize ease of use and expandability, within OpenFaaS's serverless computing framework. As a multifaceted auxiliary tool in medical scientific exploration, AIScholar accelerates the deployment of computational resources, enabling clinicians and scientific personnel to derive new insights from clinical medical data with unprecedented efficiency.
View Article and Find Full Text PDFSleep disorders have become a significant health concern in modern society. To investigate and diagnose sleep disorders, sleep analysis has emerged as the primary research method. Conventional polysomnography primarily relies on cerebral electroencephalography (EEG) and electromyography (EMG) for sleep stage scoring, but manual scoring is time-consuming and subjective.
View Article and Find Full Text PDFBrain alterations associated with illness severity in schizophrenia remain poorly understood. Establishing linkages between imaging biomarkers and symptom expression may enhance mechanistic understanding of acute psychotic illness. Constructing models using MRI and clinical features together to maximize model validity may be particularly useful for these purposes.
View Article and Find Full Text PDFIEEE Trans Neural Netw Learn Syst
September 2024
Suspended particles in hazy medium absorb and scatter light, severely degrading imaging quality. Numerous single-image dehazing methods have been proposed to reconstruct clear images from hazy ones. However, most of them focus on increasing depth and width to improve dehazing performance, which incurs high computation and energy costs.
View Article and Find Full Text PDFIEEE J Biomed Health Inform
August 2024
Medical image segmentation is a fundamental task in many clinical applications, yet current automated segmentation methods rely heavily on manual annotations, which are inherently subjective and prone to annotation bias. Recently, modeling annotator preference has garnered great interest, and several methods have been proposed in the past two years. However, the existing methods completely ignore the potential correlation between annotations, such as complementary and discriminative information.
View Article and Find Full Text PDFCoronary artery segmentation is crucial for physicians to identify and locate plaques and stenosis using coronary computed tomography angiography (CCTA). However, the low contrast of CCTA images and the intricate structures of coronary arteries make this task challenging. To address these difficulties, we propose a novel model, the DFS-PDS network.
View Article and Find Full Text PDFOsteomyelitis (OM) is a major challenge in orthopedic surgery. The diagnosis of OM is based on imaging and laboratory tests, but it still presents some limitations. Therefore, a deeper comprehension of the pathogenetic mechanisms could enhance diagnostic and treatment approaches.
View Article and Find Full Text PDFChronic prostatitis-induced excessive inflammation and oxidative stress (OS) damage substantially affect men's quality of life. However, its treatment remains a major clinical challenge. Therefore, the identification of drugs that can decrease chronic prostatitis and oxidative stress targets is urgent and essential.
View Article and Find Full Text PDFIn the evaluation of cervical spine disorders, precise positioning of anatomo-physiological hallmarks is fundamental for calculating diverse measurement metrics. Despite the fact that deep learning has achieved impressive results in the field of keypoint localization, there are still many limitations when facing medical image. First, these methods often encounter limitations when faced with the inherent variability in cervical spine datasets, arising from imaging factors.
View Article and Find Full Text PDFIEEE Trans Neural Netw Learn Syst
July 2024
Deep reinforcement learning (RL) has been widely applied to personalized recommender systems (PRSs) as they can capture user preferences progressively. Among RL-based techniques, deep Q-network (DQN) stands out as the most popular choice due to its simple update strategy and superior performance. Typically, many recommendation scenarios are accompanied by the diminishing action space setting, where the available action space will gradually decrease to avoid recommending duplicate items.
View Article and Find Full Text PDFThe quality of medical images is crucial for accurately diagnosing and treating various diseases. However, current automated methods for assessing image quality are based on neural networks, which often focus solely on pixel distortion and overlook the significance of complex structures within the images. This study introduces a novel neural network model designed explicitly for automated image quality assessment that addresses pixel and semantic distortion.
View Article and Find Full Text PDFInt J Neural Syst
September 2024
The deep neural network, based on the backpropagation learning algorithm, has achieved tremendous success. However, the backpropagation algorithm is consistently considered biologically implausible. Many efforts have recently been made to address these biological implausibility issues, nevertheless, these methods are tailored to discrete neural network structures.
View Article and Find Full Text PDFIEEE Trans Neural Netw Learn Syst
June 2024
Meta-learning aims to leverage prior knowledge from related tasks to enable a base learner to quickly adapt to new tasks with limited labeled samples. However, traditional meta-learning methods have limitations as they provide an optimal initialization for all new tasks, disregarding the inherent uncertainty induced by few-shot tasks and impeding task-specific self-adaptation initialization. In response to this challenge, this article proposes a novel probabilistic meta-learning approach called prototype Bayesian meta-learning (PBML).
View Article and Find Full Text PDFAims: Permanent pacemaker implantation and left bundle branch block are common complications after transcatheter aortic valve replacement (TAVR) and are associated with impaired prognosis. This study aimed to develop an artificial intelligence (AI) model for predicting conduction disturbances after TAVR using pre-procedural 12-lead electrocardiogram (ECG) images.
Methods And Results: We collected pre-procedural 12-lead ECGs of patients who underwent TAVR at West China Hospital between March 2016 and March 2022.
IEEE J Biomed Health Inform
August 2024
Thoracic computed tomography (CT) currently plays the primary role in pulmonary nodule detection, where the reconstruction kernel significantly impacts performance in computer-aided pulmonary nodule detectors. The issue of kernel selection affecting performance has been overlooked in pulmonary nodule detection. This paper first introduces a novel pulmonary nodule detection dataset named Reconstruction Kernel Imaging for Pulmonary Nodule Detection (RKPN) for quantifying algorithm differences between the two imaging types.
View Article and Find Full Text PDFRadiation therapy relies on quality assurance (QA) to verify dose delivery accuracy. However, current QA methods suffer from operation lag as well as inaccurate performance. Hence, to address these shortcomings, this paper proposes a QA neural network model based on branch architecture, which is based on the analysis of the category features of the QA complexity metrics.
View Article and Find Full Text PDFIEEE Trans Neural Netw Learn Syst
March 2024
Neural networks are developed to model the behavior of the brain. One crucial question in this field pertains to when and how a neural network can memorize a given set of patterns. There are two mechanisms to store information: associative memory and sequential pattern recognition.
View Article and Find Full Text PDFObjective: The aim of this study was to investigate risk factors for the severity of breast abscess during lactation.
Methods: A cross-sectional study was conducted using data from the Questionnaire survey of breast abscess patients. According to whether the maximum abscess diameter > 5 cm, the patients were divided into two groups for univariate and multivariate regression analysis.
Deep Feedforward Neural Networks (FNNs) with skip connections have revolutionized various image recognition tasks. In this paper, we propose a novel architecture called bidirectional FNN (BiFNN), which utilizes skip connections to aggregate features between its forward and backward paths. The BiFNN accepts any FNN as a plugin that can incorporate any general FNN model into its forward path, introducing only a few additional parameters in the cross-path connections.
View Article and Find Full Text PDFObjective: To elucidate the molecular mechanisms governing the effect of Tounongsan decoction (, TNS) on the pyogenic liver abscess.
Methods: Based on oral bioavailability and drug-likeness, the main active components of TNS were screened using the Traditional Chinese Medicine Systems Pharmacology platform. The GeneCard and UniProt databases were used to establish a database of pyogenic liver abscess targets.