Deoxycholic acid exacerbates intestinal inflammation by modulating interleukin-1 expression and tuft cell proportion in dextran sulfate sodium-induced murine colitis.

Background: The etiology of inflammatory bowel disease (IBD) remains unclear. However, intestinal metabolism is known to be critical in the pathogenesis of IBD. Bile acid is one of the main intestinal metabolites, and its role in the pathogenesis of IBD is worthy of investigation.

[Interlaboratory comparison for determination of arsenic in drinking water].

Objective: To analyze and evaluate the testing capability of arsenic in drinking water in the laboratories of the provincial and municipal centers for disease control and prevention across the country by implementing the interlaboratory comparison project.

Methods: The preparation method of the secondary standard materials were used as the reference for the sample preparation in the interlaboratory comparison project. The homogeneity and stability of the samples and short-term stability for simulated transportation were tested by single factor analysis of variance(ANOVA) and linear regression and mean consistency test(t test).

[Interlaboratory comparison for determination of cadmium in drinking water].

Objective: To analyze and evaluate the testing capability of cadmium in drinking water in the laboratories of the provincial and municipal centers for disease control and prevention across the country by implementing the interlaboratory comparison project.

Methods: The preparation method of the secondary standard materials were used as the reference for the sample preparation in the interlaboratory comparison project. The homogeneity and stability of the samples and short-term stability for simulated transportation were tested by single factor analysis of variance(ANOVA) and linear regression and mean consistency test(t test).

[Interlaboratory comparison for determination of lead in drinking water].

Objective: To analyze and evaluate the testing capability of lead in drinking water in the laboratories of the provincial and municipal centers for disease control and prevention across the country by implementing the interlaboratory comparison project.

Methods: The preparation method of the secondary standard materials were used as the reference for the sample preparation in the interlaboratory comparison project. The homogeneity and stability of the samples and short-term stability for simulated transportation were tested by single factor analysis of variance(ANOVA) and mean consistency test(t test).

Polyglycoside Ameliorated TNBS-Induced Colitis in Rats via Regulating Th17/Treg Balance in Intestinal Mucosa.

Purpose: To investigate the therapeutic effect of polyglycoside (TWP), a derivative from a Chinese traditional herb, on 2,4,6-trinitrobenzenesulfonic acid (TNBS)-induced colitis, in a model for inflammatory bowel disease (IBD) in rats.

Methods: TWP was administrated to Wistar rats during TNBS-induced colitis to determine its therapeutic effect on active inflammation using the Quantitative Real-Time Polymerase Chain Reaction (qRT-PCR), flow cytometry, and Western blotting. Peripheral blood CD4 T-cells were isolated from patients with ulcerative colitis (UC) and incubated with TWP to verify its immune regulation mechanism by qRT-PCR and flow cytometry.

The Degree of Ulcerative Colitis Burden of Luminal Inflammation score is superior to predicting medium- to long-term prognosis in patients with active ulcerative colitis.

Aims: The endoscopic evaluation is crucial for the management and treatment of ulcerative colitis (UC). Currently, the Mayo Endoscopic Score (MES) and the Ulcerative Colitis Endoscopic Index of Severity (UCEIS) are two major endoscopic score systems to evaluate the status of mucosal inflammation and disease activity. However, in both MES and UCEIS systems, the disease extent is not included.

Crohn's disease exacerbated by IL-17 inhibitors in patients with psoriasis: a case report.

Background: Previous studied revealed that psoriasis and Inflammatory bowel disease (IBD) have highly overlapping epidemiological characteristics, genetic susceptibility loci, disease risk factors, immune mechanisms, and comorbidities. More and more biologics have been used to treat psoriasis and IBD. Interleukin (IL)-17 inhibitors played an important role in the treatment of psoriasis, but induced and aggravated inflammatory bowel disease in some patients.

[Proficiency test for determination of anion synthetic detergent in drinking water].

Objective: To evaluate the capacity of national laboratories for determination of anion synthetic detergent in drinking water using Proficiency Testing Program.

Methods: The preparation method of the Secondary Standard Materials were used as the reference for the sample preparation in this Proficiency Testing Program. The homogeneity and stability of the samples and short-term stability for simulated transportation were tested by Single Factor Analysis of Variance(ANOVA) and Linear Regression and Mean consistency test.

[Proficiency test for determination of chlorate in drinking water].

Objective: To evaluate the capacity of national laboratories for determination of chlorate in drinking water using Proficiency Testing Program.

Methods: The preparation method of the Secondary Standard Materials were used as the reference for the sample preparation in this Proficiency Testing Program. The homogeneity and stability of the samples and short-term stability for simulated transportation were tested by Single Factor Analysis of Variance(ANOVA) and Linear Regression and Mean consistency test.

[Proficiency test for determination of iron in drinking water].

Objective: To evaluate the capacity of national laboratories for determination of iron in drinking water using Proficiency Testing Program.

Methods: The preparation method of the Secondary Standard Materials were used as the reference for the sample preparation in this Proficiency Testing Program. The homogeneity and stability of the samples and short-term stability for simulated transportation were tested by Single Factor Analysis of Variance(ANOVA) and Linear Regression and Mean consistency test.

[Proficiency test for determination of bromate in drinking water].

Objective: To evaluate the capacity of national laboratories for determination of bromate in drinking water using Proficiency Testing Program.

Methods: The preparation method of the Secondary Standard Materials were used as the reference for the sample preparation in this Proficiency Testing Program. The homogeneity and stability of the samples and short-term stability for simulated transportation were tested by Single Factor Analysis of Variance(ANOVA) and Linear Regression and Mean consistency test.

[Proficiency test for determination of tribromomethane in drinking water].

Objective: To evaluate the capacity of national laboratories for determination of tribromomethane in drinking water using proficiency testing program.

Methods: The preparation method of the secondary standard materials were used as the reference for the sample preparation in this proficiency testing program. The homogeneity and stability of the samples were tested by single factor analysis of variance( ANOVA) and linear regression.

[Proficiency test for determination of fluoride in drinking water].

Objective: To evaluate the capacity of national laboratories for determination of fluoride in drinking water using proficiency testing program.

Methods: The preparation method of the secondary standard materials were used as the reference for the sample preparation in this proficiency testing program. The homogeneity and stability of the samples were tested by single factor analysis of variance( ANOVA) and linear regression.

[Analysis results of proficiency test for determination of lindane in drinking water in 2016].

Objective: To evaluate the capacity of national laboratories for determination of lindane in drinking water using proficiency testing program.

Methods: The preparation method of the secondary standard materials were used as the reference for the sample preparation in this proficiency testing program. The homogeneity and stability of the samples were tested by single factor analysis of variance( ANOVA) and linear regression.

[Study on proficiency test for determination of aluminum in drinking water in 2016].

Objective: To evaluate the capacity of national laboratories for determination of aluminum in drinking water using proficiency testing program.

Methods: The preparation method of the secondary standard materials were used as the reference for the sample preparation in this proficiency testing program. The homogeneity and stability of the samples were tested by single factor analysis of variance( ANOVA) and linear regression.

[Proficiency test for determination of benzene in drinking water].

Objective: To evaluate the capacity of national laboratories for determination of benzene in drinking water using Proficiency Testing Program.

Methods: The preparation methods of the Secondary Standard Materials were used as the reference for the sample preparation in this Proficiency Testing Program. The homogeneity and stability of the samples were tested by Single Factor Analysis of Variance( ANOVA) and Linear Regression.

[Evaluation on the capability of testing total dissolved solids of the provincial centers for disease control and prevention].

Objective: To evaluate the Centers of Disease Control and Prevention's (CDC) provincial divisions' capabilities of detecting concentrations of organoleptic and physical parameter of total dissolved solids by adopging a quality control assessment methodology of interlaboratory comparison.

Methods: All laboratories had been divided into 2 groups of which contained 16 laboratories. Total dissolvedsolids' concentrations were assigned to 2 sample groups.

[Evaluation on the capability of testing carbon tetrachloride, benzene, methylbenzene, dimethylbenzene, p' p-DDT of the provincial centers for disease control and prevention].

Objective: To evaluate the Centers of Disease Control and Prevention's (CDC) provincial divisions' capabilities of detectingconcentrations of organic parameters such as carbon tetrachloride, benzene, methylbenzene, dimethylbenzene and pesticide parameter of p’ p-DDT in drinking water, by adopting a quality control assessment methodology of interlaboratory comparison.

Methods: All laboratories had been divided into 2 groups, each of which contained aboutl6 laboratories. Organic concentrations and pesticide concentrations were assigned to 2 sample groups.

[Analysis and research on cleaning points of HVAC systems in public places].

Objective: To analyze cleaning points of HVAC systems, and to provides scientific base for regulating the cleaning of HVAC systems.

Methods: Based on the survey results on the cleaning situation of HVAC systems around China for the past three years, we analyzes the cleaning points of HVAC systems from various aspects, such as the major health risk factors of HVAC systems, the formulation strategy of the cleaning of HVAC systems, cleaning methods and acceptance points of the air ducts and the parts of HVAC systems, the onsite protection and individual protection, the waste treatment and the cleaning of the removed equipment, inspection of the cleaning results, video record, and the final acceptance of the cleaning.

Results: The analysis of the major health risk factors of HVAC systems and the formulation strategy of the cleaning of HVAC systems is given.

Fluorine-fixing efficiency on calcium-based briquette: pilot experiment, demonstration and promotion.

Background: The fluorosis derived from coal burning is a very serious problem in China. By using fluorine-fixing technology during coal burning we are able to reduce the release of fluorides in coal at the source in order to reduce pollution to the surrounding environment by coal burning pollutants as well as decrease the intake and accumulating amounts of fluorine in the human body. The aim of this study was to conduct a pilot experiment on calcium-based fluorine-fixing material efficiency during coal burning to demonstrate and promote the technology based on laboratory research.

[A experimental study on the effect of fluorine capture of calcium based coal briquette].

Objective: To study on the fluorine capture effect of calcium based coal briquette with fluorine capture additive in coal-burning fluorosis area.

Methods: Add proper proportions of calcium based fluorine capture additive in high fluorine coal for making coal briquette were added, and were added the fluorine in coal cinder in order to reduce its emission. Meanwhile, to determine the composes of coal briquette were added, the percentage of fluorine in coal cinder and the concentration of fluoride, sulfur dioxide and PM10 were determinated, to evaluate the effect of fluorine capture and the level of door air pollution.

[The applications for Fourier transform infrared spectrum analysis technique in preventive medicine field].

This paper expatriated the applications for Fourier transform infrared spectrum analysis technique in preventive medicine field from four aspects of environmental pollution, life science, and the latest infrared analysis methods and near infrared analysis technique. In the environmental pollution field, it mainly described the advantages, the limitations and the solutions of the combined applications for gas chromatograph and Fourier transform infrared spectrum. In the life science field, it described the application for Fourier transform infrared spectrum analysis technique on protein secondary structure, membrane protein, phospholipid, nucleic acid, cell, tissue.