Electronic Health Literacy and Self-Efficacy Among Primary and Middle School Students in China: A Moderated Mediated Analysis.

Background: The Internet has become a crucial tool for learning, socializing, and entertainment for contemporary minors, and plays an increasingly prominent role in their growth. However, it has been observed that students are often unable to make good judgments about online health information and barely use the Internet to help tackle their health problems. The purpose of this study was to determine the relationship between electronic health literacy (EHL) and general self-efficacy among Chinese primary and middle school students.

The Functional Role and Prognostic Significance of TIM-3 Expression on NK Cells in the Diagnostic Bone Marrows in Acute Myeloid Leukemia.

Compared to other immune checkpoint molecules, T cell immunoglobulin domain and mucin domain-3 (TIM-3) is highly expressed on natural killer (NK) cells, but its functional role and prognostic significance in acute myeloid leukemia (AML) remains unclear. This study aims to evaluate the role of TIM-3 expression on the cytotoxic and killing capacity of NK cells and its prognostic significance in AML. AML public single-cell RNA sequencing (scRNAseq) data were used to analyze the correlation of transcript levels between (encoding TIM-3) and cytotoxic molecules in NK cells.

A Network Analysis of Emotional Intelligence in Chinese Preschool Teachers.

Emotional intelligence significantly influences various aspects of teachers' professional and personal lives, notably affecting preschoolers' social skills and emotional development during formative years. This study utilizes a network analysis approach to explore the complex relationships among four components of emotional intelligence: emotional labor, emotional regulation, professional well-being, and professional identity. Participants included 2069 frontline Chinese teachers (34 males, 2035 females; M = 28.

New Communication Technology and the Elderly: A Study on the Continuous Use of the Extreme Edition APP for Middle-Aged and Senior Citizens.

Rapidly changing digital technologies are reconfiguring the way human society lives, indicating that more and more middle-aged and older adults will lead a digital life in the future. Whether digital technology for today can effectively improve the quality of digital life of this cohort is the focus of this study. This study proposed a "cognitive-emotional-behavioral" model and situated the use of the Extreme Edition App as a cross-sectional research object.

Hepatic Steatosis Analysis in Metabolic Dysfunction-Associated Steatotic Liver Disease Based on Artificial Intelligence.

Background: Metabolic dysfunction-associated steatotic liver disease (MASLD) is characterized by the accumulation of fat in the liver, excluding excessive alcohol consumption and other known causes of liver injury. Animal models are often used to explore different pathogenic mechanisms and therapeutic targets of MASLD. The aim of this study is to apply an artificial intelligence (AI) system based on second-harmonic generation (SHG)/two-photon-excited fluorescence (TPEF) technology to automatically assess the dynamic patterns of hepatic steatosis in MASLD mouse models.

Quantitative Prediction of Protein Content in Corn Kernel Based on Near-Infrared Spectroscopy.

Rapid and accurate detection of protein content is essential for ensuring the quality of maize. Near-infrared spectroscopy (NIR) technology faces limitations due to surface effects and sample homogeneity issues when measuring the protein content of whole maize grains. Focusing on maize grain powder can significantly improve the quality of data and the accuracy of model predictions.

Effect of Different Probiotic Fermentations on the Quality of Plant-Based Hempseed Fermented Milk.

This study investigated the effects of three different single-strain probiotics XD117, LC-37, and LGG, on the quality of hempseed fermented milk. The main findings were that adding probiotics increased the inhibition rate of α-glucosidase and pancreatic lipase in hempseed fermented milk significantly. Non-targeted metabolomic correlation analysis results confirmed that 14 substances, including three flavonoids, six amino acids and their derivatives, and five short peptides, were positively correlated with the hypoglycemic and hypolipidemic activities of hempseed fermented milk.

Mass Spectrometry-Based Metabolomics Investigation on Two Different Seaweeds Under Arsenic Exposure.

Arsenic is a common toxic heavy metal contaminant that is widely present in the ocean, and seaweeds have a strong ability to concentrate arsenic, posing a potential risk to human health. This study first analyzed the arsenic content in two different seaweeds and then used an innovative method to categorize the seaweeds into low-arsenic and high-arsenic groups based on their arsenic exposure levels. Finally, a non-targeted metabolomic analysis based on mass spectrometry was conducted on seaweed from different arsenic exposure groups.

Strategies and Methodologies for Improving Toughness of Starch Films.

Starch films have attracted increasing attention due to their biodegradability, edibility, and potential use as animal feed from post-products. Applications of starch-based films include food packaging, coating, and medicine capsules. However, a major drawback of starch-based films is their brittleness, particularly under dry conditions, caused by starch retrogradation and the instability of plasticizers.

Exploring the Impact of Different Strains on the Flavor Profile of Greengage Alcoholic Beverage Using GC-E-Nose, HS-GC-IMS, and HS-SPME-GC-MS.

Greengage alcoholic beverage (GAB) is gaining popularity for its distinctive fruity aroma and nutritional benefits. The strain applied for fermentation significantly influences the metabolic production of aroma compounds, making the selection of strains to be critical for enhancing the unique flavor profile of the GAB in commercial production. In this study, the effects of two common commercial strains (SY, EC-1118) and two laboratory-derived strains (ET008-c54, NM-8) on the flavor profile of the GAB were investigated.

Genetic Mapping by 55K Single-Nucleotide Polymorphism Array Reveals Candidate Genes for Tillering Trait in Wheat Mutant .

Background: The tiller number is a key agronomic trait for increasing the yield potential of wheat ( L.). A number of quantitative trait loci (QTLs) and key genes controlling tillering have been identified, but the regulatory mechanisms remain unclear.

The Chicken Promoter and Its Regulation by MYC and HIF1A.

Background: Histone deacetylase 4 () is a member of the class II histone deacetylase family, whose members play a crucial role in various biological processes. An in-depth investigation of the transcriptional characteristics of chicken can provide fundamental insights into its function.

Methods: We examined expression in chicken embryonic stem cells (ESC) and spermatogonial stem cells (SSC) and cloned a 444 bp fragment from upstream of the chicken transcription start site.

Complexity Analysis and Control of Output Competition in a Closed-Loop Supply Chain of Cross-Border E-Commerce Under Different Logistics Modes Considering Chain-to-Chain Information Asymmetry.

To investigate the dynamic complexity of chain-to-chain output decisions in a closed-loop supply chain system of cross-border e-commerce (CBEC), this study decomposes the system into four product-market (PM) chains, based on the e-commerce platform's information-sharing strategy and the manufacturer's selected logistics mode (direct mail or bonded warehouse). By combining game theory with complex systems theory, discrete dynamic models for output competition among PM chains under four scenarios are constructed. The Nash equilibrium solution and stability conditions of the models are derived according to the principles of nonlinear dynamics.

Performance Analysis of Troposphere Scattering Communication Channel with Chirp-BOK Modulation.

By utilizing chirp-BOK (binary orthogonal keying) modulation into a troposphere scattering communication system, a lower demodulation threshold can be achieved with excellent linear frequency modulation properties in a strong noise and weak signal environment. Firstly, the bit error rate (BER) formula of chirp-BOK modulation over a Rayleigh fading channel was derived theoretically. Then, the BER performance with different chirp-BOK parameters were numerically calculated.

Advancing Continuous Distribution Generation: An Exponentiated Odds Ratio Generator Approach.

This paper presents a new methodology for generating continuous statistical distributions, integrating the exponentiated odds ratio within the framework of survival analysis. This new method enhances the flexibility and adaptability of distribution models to effectively address the complexities inherent in contemporary datasets. The core of this advancement is illustrated by introducing a particular subfamily, the "Type 2 Gumbel Weibull-G family of distributions".

Control of a New Financial Risk Contagion Dynamic Model Based on Finite-Time Disturbance.

With the widespread application of chaotic systems in many fields, research on chaotic systems is becoming increasingly in-depth. This article first proposes a new dynamic model of financial risk contagion based on financial principles and discusses some basic dynamic characteristics of the new chaotic system, such as equilibrium points, dissipativity, Poincaré diagrams, bifurcation diagrams, etc. Secondly, with the consideration of privacy during data transmission, the method was designed to protect the privacy of controlled systems in finite time based on perturbation.

The Role of Gut Microbiome in Irritable Bowel Syndrome: Implications for Clinical Therapeutics.

Irritable bowel syndrome (IBS) is a functional gastrointestinal disorder (FGID) characterized by chronic or recurrent gastrointestinal symptoms without organic changes, and it is also a common disorder of gut-brain interaction (DGBIs).. The symptoms of IBS not only affect the quality of life for individual patients but also place a significant burden on global healthcare systems.

Mitophagy in Doxorubicin-Induced Cardiotoxicity: Insights into Molecular Biology and Novel Therapeutic Strategies.

Doxorubicin is a chemotherapeutic drug utilized for solid tumors and hematologic malignancies, but its clinical application is hampered by life-threatening cardiotoxicity, including cardiac dilation and heart failure. Mitophagy, a cargo-specific form of autophagy, is specifically used to eliminate damaged mitochondria in autophagosomes through hydrolytic degradation following fusion with lysosomes. Recent advances have unveiled a major role for defective mitophagy in the etiology of DOX-induced cardiotoxicity.

Integrated Single-Cell Analysis Revealed Novel Subpopulations of Foamy Macrophages in Human Atherosclerotic Plaques.

Foam cell formation is a hallmark of atherosclerosis, yet the cellular complexity within foam cells in human plaques remains unexplored. Here, we integrate published single-cell RNA-sequencing, spatial transcriptomic, and chromatin accessibility sequencing datasets of human atherosclerotic lesions across eight distinct studies. Through this large-scale integration of patient-derived information, we identified foamy macrophages enriched for genes characteristic of the foamy signature.

Urinary Tract Infections Detection with Molecular Biomarkers.

Urinary tract infection (UTI) is the most prevalent kind of pathogenic bacteria infection, and the midstream urine culture is regarded as the gold standard in UTI diagnosis. Recently, even with modern media and techniques such as polymerase chain reaction (PCR), urinary cultures still create a considerable workload for hospital laboratories. Other UTI-detecting methods, such as flow cytometry and lateral flow immunoassay, suffer from various drawbacks like long time consumption and low sensitivity.

Colon Cancer Rates Among Asian Americans: A 2017-2021 Epidemiological Analysis.

Colon cancer (CC) is a significant public health concern. With Asian Americans (AAs) representing a rapidly growing demographic in the United States, our study examined CC prevalence among AAs. The study merged the 2017-2021 Medical Expenditure Panel Survey and County Health Ranking.

Melatonin Enhances the Low-Calcium Stress Tolerance by Regulating Brassinosteroids and Auxin Signals in Wax Gourd.

In plants, calcium (Ca) serves as an essential nutrient and signaling molecule. Melatonin is a biologically active and multi-functional hormone that plays an important role in improving nutrient use efficiency. However, its involvement in plant responses to Ca deficiency remains largely unexplored.

Biofluid-Derived Exosomal LncRNAs: Their Potential in Obesity and Related Comorbidities.

Obesity has escalated into a critical global health crisis, tripling in prevalence since the mid-1970s. This increase mirrors the rise in metabolic-associated diseases such as type 2 diabetes (T2D) and its complications, certain cancers, and cardiovascular conditions. While substantial research efforts have enriched our understanding and led to the development of innovative management strategies for these diseases, the suboptimal response rates of existing therapies remain a major obstacle to effectively managing obesity and its associated conditions.

Effects of Extract on Growth Performance, Nutrient Apparent Digestibility, Serum Parameters, and Fecal Microbiota in Finishing Pigs.

This study investigated the effects of extract (FAE) on growth performance, nutrient apparent digestibility, serum parameters, fecal microbial composition, and short-chain fatty acids (SCFAs) in finishing pigs. In total, 75 Duroc × Landrace × Yorkshire pigs (equally divided by sex), with an initial body weight of 79.49 ± 4.

Growth Superiority and Genetic Characterization of the Hybrid from Female Ussuri Catfish () and Male Longsnout Catfish ().

Crossbreeding is a traditional breeding technique and has been performed successfully in many fish species. However, distant hybridization between different genera is hard to be successful because of reproductive isolation. In this study, diploid hybrids (PL) were successfully derived from the hybridization of Ussuri catfish (, PU, ♀, 2n = 52) and longsnout catfish (, LL, ♂, 2n = 52).