Publications by authors named "Xiaojian Yu"

Background: Researchers gradually focus on the relationship between phage and cancer.

Objective: To summarize the research hotspots and trends in the field of bacteriophage and cancer.

Methods: The downloaded articles were searched from the Web of Science Core Collection database from January 2008 to June 2023.

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Background: The advancements in artificial intelligence (AI) technology for image recognition were propelling molecular pathology research into a new era.

Objective: To summarize the hot spots and research trends in the field of molecular pathology image recognition.

Methods: Relevant articles from January 1st, 2010, to August 25th, 2023, were retrieved from the Web of Science Core Collection.

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Background: Gut bacteria are related to colorectal cancer (CRC) and its clinicopathologic characteristics.

Objective: To develop gut bacterial subtypes and explore potential microbial targets for CRC.

Methods: Stool samples from 914 volunteers (376 CRCs, 363 advanced adenomas, and 175 normal controls) were included for 16S rRNA sequencing.

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Background: More than 90% of colorectal cancer (CRC) arises from advanced adenomas (AA) and gut microbes are closely associated with the initiation and progression of both AA and CRC.

Objective: To analyze the characteristic microbes in AA.

Methods: Fecal samples were collected from 92 AA and 184 negative control (NC).

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Membrane potential (V) is a key bioelectric property of non-excitable cells that plays important roles in regulating cell proliferation. However, the regulation of V itself remains largely unexplored. We found that, under nutrient starvation, during which cell division is inhibited, MKN45 gastric cancer cells were in a hyperpolarized state associated with a high intracellular chloride concentration.

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Over the past decades, we have witnessed the growth demands of portable lab-on-chip biosensors. These lab-on-chip devices are mostly powered by battery, and intelligent power management systems are required to provide supply voltage for different functional units on biosensors (e.g.

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Generating renewable energy while sequestering CO using algae has recently attracted significant research attention, mostly directing towards biological methods such as systems biology, genetic engineering and bio-refining for optimizing algae strains. Other approaches focus on chemical screening to adjust culture conditions or culture media. We report for the first time the physiological changes of algal cells in response to a novel form of mechanical stimulation, or a pulsed wave at the frequency of 1.

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The most widespread type of RNA editing, conversion of adenosine to inosine (A→I), is catalyzed by two members of the adenosine deaminase acting on RNA (ADAR) family, ADAR1 and ADAR2. These enzymes edit transcripts for neurotransmitter receptors and ion channels during adaption to changes in the physical environment. In the primitive crustacean Artemia, when maternal adults are exposed to unfavorable conditions, they release diapause embryos to withstand harsh environments.

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Autophagy is an essential homeostatic process by which cytoplasmic components, including macromolecules and organelles, are degraded by lysosome. Increasing evidence suggests that phosphorylated AMP-activated protein kinase (p-AMPK) and target of rapamycin (TOR) play key roles in the regulation of autophagy. However, the regulation of autophagy in quiescent cells remains unclear, despite the fact that autophagy is known to be critical for normal development, regeneration, and degenerative diseases.

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MicroRNAs (miRs) are short, non-coding RNAs with post-transcriptional regulatory functions. Previous studies have demonstrated that miR-34c is involved in diverse biological processes, including carcinogenesis. The aim of the present study was to investigate the role of miR-34c and its target genes in hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC).

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Background & Aims: AIM2 plays an important role in innate immunity, but its role in regulating the immune response to hepatitis B virus (HBV) is unknown. We hypothesized that AIM2 expression is positively correlated with HBV-mediated inflammation in patients with HBV-associated glomerulonephritis (HBV-GN), potentiating inflammation and leading to renal damage. We therefore analyzed the expression of AIM2 and inflammatory factors in HBV-GN tissues and cell lines relative to the inflammatory response to HBV infection and HBV status.

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In this paper, a simple and adaptive thermoacoustic sensor was designed to measure Low Intensity Pulsed Ultrasound (LIPUS). Compared to other thermoacoustic sensor designs, our novelty lies in (i) integrating an ultrasound medium layer during the measurement to simplify the complicated set-up procedures and (ii) taking the effect of ambient temperatures into design consideration. After measuring temperature increases with various ambient temperatures under different ultrasound intensities, a relationship among ultrasound intensities, ambient temperatures and coefficients of temporal temperature changes was calculated.

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Although the radiation force balance is the gold standard for measuring ultrasound intensity, it cannot be used for real-time monitoring in certain settings, for example, bioreactors or in the clinic to measure ultrasound intensities during treatment. Foreseeing these needs, we propose a close-proximity thermoacoustic sensor. In this article, we describe the design, characterization, testing and implementation of such a sensor.

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The semi-stadium system is composed of a semicircular cap and a rectilinear platform. In this study, a dynamic model of the side, position, and angle variables is applied to investigate the acoustic ray chaos of the architectural semi-stadium system. The Lyapunov exponent is calculated in order to quantitatively describe ray instability.

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