Publications by authors named "Vijayasurya"
Article Synopsis
- * There are not enough vaccines to help prevent these diseases, so safe and effective medications are super important, but some parasites are becoming resistant to medicines.
- * Researchers are looking for new ways to find drugs that can help, including using existing medicines in new ways, which can be cheaper and more efficient. They found that some drugs may work better for other diseases than their original purpose.
Aminoacyl-tRNA synthetases (AaRSs) are valuable "housekeeping" enzymes that ensure the accurate transmission of genetic information in living cells, where they aminoacylated tRNA molecules with their cognate amino acid and provide substrates for protein biosynthesis. In addition to their translational or canonical function, they contribute to nontranslational/moonlighting functions, which are mediated by the presence of other domains on the proteins. This was supported by several reports which claim that AaRS has a significant role in gene transcription, apoptosis, translation, and RNA splicing regulation.
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