[Degree of lipid peroxidation and vitamin E level during the treatment of peptic ulcer].

The study of 468 ulcer patients treated by laser irradiation plus choline blocking agents with adjuvant alpha-tocopherol antioxidants (alpha-tocopherol acetate, wild rose and sea-buckthorn oils) provided evidence in favour of the antioxidants addition. Combination of hyperbaric oxygenation (5-6 sessions) or riboxin with choline blocking agents made antioxidants unnecessary. Biochemical findings (vitamin E and malonic dialdehyde concentrations), electron microscopic, ++histo-enzyme and amino acids studies supported the clinical evidence.

[The vitamin E concentration and lipid peroxidation status of patients with peptic ulcer undergoing laser therapy].

The authors established the necessity that during laser therapy of patients with ulcer disease this treatment should be associated with the use of cholinolytic agents and antioxidants of the alpha-tocopherol type. As the authors' data indicate in ulcer disease a deficit of vitamin E and an enhancement of lipid peroxidation is present.