This research describes the synthesis and characterization of a molecularly imprinted polymer (MIP) as a candidate for the transdermal delivery of curcumin. The MIP was synthesized through precipitation polymerization using methacrylic acid as the functional monomer and ethylene glycol dimethacrylate as the cross-linking agent. MIP characterization studies were conducted using SEM-EDX and FTIR spectroscopy to determine the morphology and interaction between curcumin and polymers.
View Article and Find Full Text PDFBordetella pertussis infection is a highly contagious respiratory disease that can cause complications such as pneumonia and death. A total of 62,646 cases of pertussis worldwide were reported by WHO in 2022. This study aimed to obtain the pertussis seroprevalence and sociodemographic data in children aged 1-14 years and its association factors in the community based on Riskesdas 2013 and 2018.
View Article and Find Full Text PDFIntroduction: The COVID-19 pandemic has impacted technical workers who work more often in the field (e.g., engineering, mechanical, health safety environment (HSE), quality control, and production workers) with increasingly complex workloads and work pressures.
View Article and Find Full Text PDFTrypanosoma evansi is reportedly divided into two genotypes: types A and B. The type B is uncommon and reportedly limited to Africa: Kenya Sudan, and Ethiopia. In contrast, type A has been widely reported in Africa, South America, and Asia.
View Article and Find Full Text PDFFour strains (SB-PR, SB-RS, SB-RD, and SB-RM) of Trypanosoma evansi (T. evansi) were used in this study. SB-PR is known to be trypanocide-sensitive, while the others are trypanocide-resistant to suramin, diminazene diaceturate, and melarsomine hydrochloride, respectively.
View Article and Find Full Text PDFBackground: Vitamin D supplementation or sun exposure increase pregnant women's Calcidiol levels, lower the blood pressures and increase birth weight. We aimed to compare the effects between sun exposure and vitamin D supplementation on pregnant women's Calcidiol levels, blood pressures and newborns' anthropometric indices.
Methods: This randomized clinical trial was conducted on 108 pregnant women at 20 wk of gestation on 2021's dry season in Semarang City, Indonesia.
Background: Hepatitis B is a viral infection that has a high prevalence in Indonesia. The Ministry of Health of Indonesia has conducted a national vaccination program for hepatitis B. In order to evaluate the success of the hepatitis B vaccination in Indonesia, a community study based on basic health research (Riskesdas) was performed nationwide since 2007 for five year period in 2007, 2013, and 2018.
View Article and Find Full Text PDFAntimicrobial resistance is the rising global health issue that should not be ignored. This problem needs to be addressed and professionally handled since it is starting to threaten global health, which eventually could lead to disaster. Extended spectrum beta lactamase (ESBL)-producing bacteria were found threatening lives, since most antibiotics were found to not be effective in treating patients with infections caused by those bacteria.
View Article and Find Full Text PDFThe COVID-19 pandemic has significantly impacted many sectors, including the education sector. After in-person school activities were suspended due to the pandemic, a number of educational institutions in Indonesia reported concerns in implementing online learning due to the institutions' unpreparedness. This issue may potentially induce mental health disorders among students and triggers long-term stress.
View Article and Find Full Text PDFIntroduction: Numerous studies have reported respiratory impairment by exposure to fine particulate matter (PM). However, limited studies investigated its effects on fiber cement roof workers. Thus, our study evaluated the impact of PM on pulmonary impairments among workers and its risk factors.
View Article and Find Full Text PDFHost genetic factors, such as the genes for various cytokines and adhesion molecules, play a significant role in determining susceptibility to malaria infection. Polymorphisms in host genes have been correlated with malaria infection in both African and Asian regions. The purpose of this study was to investigate the association between both cytokine and adhesion molecule genotypes with susceptibility to malaria infection in humans.
View Article and Find Full Text PDFThe search for alternative methods for the production of new materials or fuel from renewable and sustainable biomass feedstocks has gained increasing attention. In this study, (nipa palm) fronds from agricultural residues were evaluated to produce pure cellulose by combining prehydrolysis for 1-3 h at 150 °C, sulfur-free soda cooking for 1-1.5 h at 160 °C with 13-25% active alkali (AA), 0.
View Article and Find Full Text PDFBackground: Difficulties in exercising have occurred for the entire world's population during this COVID-19 pandemic, especially in the second wave at the end of 2021. Most worrying is the lack of physical activity in young adults, as lack of exercise will increase the risk of noncommunicable diseases in the future. The youth such as university student can be agents of change, to increase physical activity, from sedentary to sport life.
View Article and Find Full Text PDF() is the causative agent of diphtheria. The main virulence factor of is diphtheria toxin, which is encoded by the gene and regulated by the gene. The and genes are used as genetic markers to identify bacteria causing diphtheria by PCR.
View Article and Find Full Text PDFPertussis cases have been reported most frequently in developed countries, but they are predicted to be the most prevalent in developing countries. Indonesia, a developing country, routinely conducts case-based surveillance for pertussis. We reviewed the data on pertussis cases and close contacts based on clinical sample documents examined in the National Reference Laboratory for pertussis, Indonesia (2016-2020).
View Article and Find Full Text PDFEnvironmental awareness (EA) is a part of character education ignored by most students. This indifference tends to affect other students' by not only in protecting and preserving the current environment but also in preventing and repairing the damage that occurs in the environment. This research analyses students' EA profile, based on the findings of LISREL 8.
View Article and Find Full Text PDFBackground: Vaccination increase immunity against diphtheria, yet will decrease by aging. Therefore, boosters are needed to be done regularly.
Objectives: This study aims to determine the immunity to diphtheria for the population of 16 years old and above.
Objective: The study aimed to explore factors associated with prelabor rupture of membrane (PROM) and mode of delivery of PROM at secondary health care.
Methods: It was a retrospective case-control study within a year observational period. Data were collected from medical records at St.
Objective: The study aims to compare levels NO, the ROT, and BMI values in preeclampsia and normotension.
Method: This study was an observational analytical study that combined the draft case-control study and a cross-sectional study (hybrid method) conducted in February-June 2020. This study was conducted in the Hospital Dr.
Objective: This study aims to determine the correlation between Endothelin-1 levels and mean arterial pressure (MAP) with preeclampsia so that their combination can be used as the predictor of PE in early pregnancy.
Method: This study used a cross-sectional study with a case-control design carried out in February to June 2020 in several hospitals and health centers in Makassar city, namely Dr. Wahidin Soedirohusodo General Hospital, Hasanuddin University State University Hospital, health center Bara Baraya, health center Mamajang, and health center Antang.
Community perceptions of early-stage pandemics may have significant implications for subsequent disease control and management. Perceptions of COVID-19 among Indonesian citizens were assessed 2 months after the first reported case in the country. The study used an online survey tool, which was adapted from a standardized questionnaire for risk perception of an infectious disease outbreak.
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