Association of Food Addiction With Obesity in Young Adults Belonging to Urban and Rural Populations.

Background Food addiction (FA), where an individual displays a loss of control over the consumption of calorie-dense foods (refined carbohydrates, fats), is proposed to be like substance-use disorders with the experience of cravings, reduced control over intake, increased impulsivity, and altered reward-sensitivity. FA may also be associated with obesity. This study aimed to determine the prevalence of FA in urban and rural areas, and the proportion of obesity in young adults with FA.

The effect of curcuma longa extract and significance of mordant as an alternative for eosin in H and E: A comparative study.

Background And Aim: Hematoxylin and Eosin (H and E) staining is a common and routine staining method used in Histopathology. In origin, Hematoxylin is natural and Eosin is a synthetic dye. Synthetic dyes are widely accepted due to its staining efficiency.

Single injection of very mild dose botulinum toxin in the vastus lateralis improves testicular spermatogenesis and sperm motility in ageing experimental mice.

Background: Botulinum toxin (BoNT) is a widely used therapeutic agent that blocks the excessive release of acetylcholine at the neuromuscular junction. Previously, repeated intracremasteric injections and slight overdose of BoNT have been reported to induce adverse effects in the testicular parameter of experimental rodents. However, a mild dose of BoNT is highly beneficial against skin ageing, neuromuscular deficits, overactive urinary bladder problems, testicular pain and erectile dysfunctions.

Manual extraction is superior to power tools when removing stripped titanium locking screws.

Introduction: Removal of screws from a titanium locking plate is often difficult once the screw has seized and the head is damaged. Such stripped screws are removed with an extraction screw, which can be used manually or on power. We aim to compare the extraction rates using both these methods.

BOTOX® counteracts the innate anxiety-related behaviours in correlation with increased activities of key antioxidant enzymes in the hippocampus of ageing experimental mice.

Cholinergic crisis and oxidative stress in the hippocampus of the brain have been known to induce anxiety disorders upon ageing. BOTOX® is a widely used therapeutic form of botulinum neurotoxin that acts by inhibiting the release of acetylcholine (ACh) from the nerve terminals at the neuromuscular junction. BOTOX® can migrate from the muscle to the brain through retrograde axonal transport and modulate neuroplasticity.

Fatigue fracture of the femoral component in total knee replacement.

Background: Fracture of femoral component in total knee arthroplasty (TKA) has become a rare complication with improvements in metal alloy manufacturing technology.

Methodology: We report two cases of fracture of femoral components 9 and 10 years after primary TKA. The Buechel-Pappas (BP) knee system used in our two cases were designed by the same team who designed the LCS TKA implants.

Assessment of ovarian follicular dynamics and folliculogenesis associated endocrine profiles following gonadotropin stimulation in the bonnet monkey.

We evaluated ovarian follicular dynamics in bonnet monkeys by employing trans-abdominal ultrasonography. Following the administration of human follicle stimulating hormone (hFSH) and/or human menopausal gonadotropin (hMG), multiple follicular development was assessed and their numbers, size and growth profiles were monitored. The ultrasonograms showed that the follicular antrum appeared distinctly anechoic with well-defined hyperechoic borders.

NMR based serum metabolomics reveals a distinctive signature in patients with Lupus Nephritis.

Management of patient with Lupus Nephritis (LN) continues to remain a challenge for the treating physicians because of considerable morbidity and even mortality. The search of biomarkers in serum and urine is a focus of researchers to unravel new targets for therapy. In the present study, the utility of NMR-based serum metabolomics has been evaluated for the first time in discriminating LN patients from non-nephritis lupus patients (SLE) and further to get new insights into the underlying disease processes for better clinical management.

Principles and Methods of Preparation of Platelet-Rich Plasma: A Review and Author's Perspective.

The utility of platelet-rich plasma (PRP) has spanned various fields of dermatology from chronic ulcer management to trichology and aesthetics, due to its role in wound healing. Though PRP is being used over a long time, there is still confusion over proper terminology to define, classify and describe the different variations of platelet concentrates. There is also a wide variation in the reported protocols for standardization and preparation of PRP, in addition to lack of accurate characterization of the tested products in most articles on the topic.

Case Report: Solitary mastocytoma treated successfully with topical tacrolimus.

Solitary mastocytoma, a rare dermatological entity accounts for 10-15% of cutaneous mastocytosis. We report a rare case of solitary mastocytoma presenting at birth, treated successfully with topical tacrolimus. Along with reassurance and strict avoidance of triggering factors, no recurrence was reported within the one year follow-up period.

Profile of lesions in cystoscopic bladder biopsies: a histopathological study.

Unlabelled: Aim and Introduction: Urinary bladder lesions, non-neoplastic and neoplastic, are collectively responsible for significant morbidity and mortality throughout the world. The present study aimed to study the histopathology of various lesions of the bladder through cystoscopic biopsies.

Material And Methods: The present prospective study aimed to study the histopathology of various lesions of the urinary bladder through cystoscopic biopsies.

A randomized evaluator blinded study of effect of microneedling in androgenetic alopecia: a pilot study.

Introduction: Dermal papilla (DP) is the site of expression of various hair growth related genes. Various researches have demonstrated the underlying importance of Wnt proteins and wound growth factors in stimulating DP associated stem cells. Microneedling works by stimulation of stem cells and inducing activation of growth factors.

The efficiency of the serum prostate specific antigen levels in diagnosing prostatic enlargements.

Background: The objective of this study was to evaluate the serum PSA levels in patients presenting with enlarged prostate and to evaluate the efficiency of serum PSA to diagnose and differentiate benign and malignant enlargements.

Methods: The authors evaluated the patients coming in surgical OPD with enlarged prostate and were advised to undergo serum PSA testing.

Results: The efficiency of serum PSA to differentiate Benign and malignant lesions was 97.