Delivering non-communicable disease services through primary health care in selected south Asian countries: are health systems prepared?

In the south Asian region, delivering non-communicable disease (NCD) prevention and control services through existing primary health-care (PHC) facilities is urgently required yet currently challenging. As the first point of contact with the health-care system, PHC offers an ideal window for prevention and continuity of care over the life course, yet the implementation of PHC to address NCDs is insufficient. This review considers evidence from five south Asian countries to derive policy-relevant recommendations for designing integrated PHC systems that include NCD care.

Exploring the viability of anti-microbial, superhydrophobic jute bags as an approach to sustainable food packaging system.

Jute in food packaging offers several advantages, including cost-effectiveness, biodegradability, renewability, and low environmental impact. Nevertheless, its hydrophilic characteristic makes it susceptible to airborne humidity and precipitation moisture. We combated this by chemically treating jute to make it water-resistant.

Recent Development on Copper-Sensor and its Biological Applications: A Review.

Metal ion recognition is one of the most prospective research topics in the field of chemical sensors due to its wide range of clinical, biological and environmental applications. In this context, hydrazones are well known compounds that exhibit metal sensing and several biological properties due to the presence of N=CH- bond. Some of the biological properties includes anti-cancer, anti-tumor, anti-oxidant, anti-microbial activities.

Rising pharmaceutical innovation in the Global South: a landscape study.

Background: There is growing interest in pharmaceutical innovation in low- and middle-income countries (LMICs), but information on existing activities, capacities, and outcomes is scarce. We mapped available data at the global level, and studied the national pharmaceutical innovation systems of Bangladesh and Colombia to shed light on pharmaceutical research and development (R&D) in the Global South, including challenges and prospects, to help fill existing knowledge gaps.

Methods: We gathered and analyzed data from three types of sources: literature, semi-structured interviews with key informants, and publicly available data on R&D funding, R&D scientific capacity measured by human resources, and clinical trial activities.

WGS-based screening of the co-chaperone protein DjlA-induced curved DNA binding protein A (CbpA) from a new multidrug-resistant zoonotic mastitis-causing Klebsiella pneumoniae strain: a novel molecular target of selective flavonoids.

The research aimed to establish a multidrug-resistant Klebsiella pneumoniae-induced genetic model for mastitis considering the alternative mechanisms of the DjlA-mediated CbpA protein regulation. The Whole Genome Sequencing of the newly isolated K. pneumoniae strain was conducted to annotate the frequently occurring antibiotic resistance and virulence factors following PCR and MALDI-TOF mass-spectrophotometry.

Sustainable approach to oil recovery from oil spills through superhydrophobic jute fabric.

Ecosystems suffer from increased oil exploitation and frequent oil spills, which calls for effective, environment-friendly, and economically viable solutions. To address this, abandoned gunny sacks as the concerned jute fabric were superhydrophobically (water contact angle ∼159°) modified, incorporating titanium dioxide (TiO) nanoparticles and hexadecyltrimethoxysilane (HDTMS), rendering a facile drop casting procedure. The modified superhydrophobic-superoleophilic jute fabric has been identified as a high-performance filter with superior reusability that can separate oil-water mixtures in challenging environmental conditions (including potent acidic, alkaline, highly saline, aqueous, frigid, and blistering water environments) while maintaining high separation efficiency.

CBCT Evaluation of Lingual Foramen and its Anatomic Variations in Northeast Indian Population.

Background: The identification of nearby neurovascular structures is a vital part of dental implant treatment planning. Commonly two implants are placed in the mandibular inter foraminal region to support the overdenture. Placing dental implants in this region is considered relatively safe.

Recurrent Oral Ulcers and Its Association With Stress Among Dental Students in the Northeast Indian Population: A Cross-Sectional Questionnaire-Based Survey.

Aim The term "aphthous" is derived from the Greek word "aphtha," which means ulceration. The cause of aphthous ulcers is multifactorial, but emotional stress is one of the most important risk factors for its occurrence in young individuals. The aim of this study was to evaluate the association of recurrent oral ulcers (ROUs) with stress among dental students in the Northeast Indian Population.

Oncoinformatic screening of the gene clusters involved in the HER2-positive breast cancer formation along with the in silico pharmacodynamic profiling of selective long-chain omega-3 fatty acids as the metastatic antagonists.

The HER2-positive patients occupy ~ 30% of the total breast cancer patients globally where no prevalent drugs are available to mitigate the frequent metastasis clinically except lapatinib and neratinib. This scarcity reinforced researchers' quest for new medications where natural substances are significantly considered. Valuing the aforementioned issues, this research aimed to study the ERBB2-mediated string networks that work behind the HER2-positive breast cancer formation regarding co-expression, gene regulation, GAMA-receptor-signaling pathway, cellular polarization, and signal inhibition.

Investigating the interaction between inter-locus and intra-locus sexual conflict using hemiclonal analysis in Drosophila melanogaster.

Background: Divergence in the evolutionary interests of males and females leads to sexual conflict. Traditionally, sexual conflict has been classified into two types: inter-locus sexual conflict (IeSC) and intra-locus sexual conflict (IaSC). IeSC is modeled as a conflict over outcomes of intersexual reproductive interactions mediated by loci that are sex-limited in their effects.

Lateral epicondylitis: Are we missing out on radial nerve involvement? A cross-sectional study.

Introduction: Lateral epicondylitis (LE) is a common ailment causing pain and functional limitations. There is an inadequate understanding of its etiopathogenesis. Involvement of the radial nerve (RN) as the primary causative factor for this condition remains debatable.

Water hyacinth for energy and environmental applications: A review.

This review is focused on the sustainable management of harvested water hyacinth (WH) via thermochemical conversion to carbonaceous materials (CMs), biofuels, and chemicals for energy and environmental applications. One of the major challenges in thermochemical conversion is to guarantee the phytoremediation performance of biochar and the energy conversion efficiency in biowaste-to-energy processes. Thus, a circular sustainable approach is proposed to improve the biochar and energy production.

Sub 10 nm CoO nanoparticle-decorated graphitic carbon nitride for solar hydrogen generation efficient charge separation.

Solar hydrogen generation is one of the most compelling concepts in modern research to address both the energy and environmental issues simultaneously for the survival of the human race. A Type II heterojunction (CoO-GCN) was fabricated by decorating sub 10 nm CoO nanoparticles (NPs) on the graphitic carbon nitride (GCN) surface. It exhibited improved absorption of UV-VIS light and efficiently separate the photogenerated electrons and holes in opposite directions.