Publications by authors named "Sirguleng"

Article Synopsis
  • The study used metabonomics to investigate liver and kidney toxicity caused by the drug garidi-5 in rats.
  • The research involved administering garidi-5 to rats for 28 days and analyzing their serum, liver, and kidney samples to identify changes in metabolites linked to toxicity.
  • Key findings indicated 52, 64, and 54 different metabolites in the high-dose group's samples, suggesting garidi-5 affects various metabolic pathways and identifies several potential biomarkers for liver and kidney toxicity.
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Objectives: Consumers' oral physiology and salivary properties are greatly dependent on dietary backgrounds, and this in turn may impact food perception and preferences. Scarce studies are available on the oral physiology and salivary rheology of Chinese participants with different dietary and ethnic backgrounds.

Design: This study examined two ethnic groups, Chinese Han and Chinese Mongolian healthy young adults, and explored the differences in oral physiology and salivary rheological properties.

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Saliva is an important component of food oral processing affecting the initial digestion and the formation of food bolus. It has been speculated that salivary biochemical properties could directly influence one's dietary habits, and vice versa. To date, there are few studies that investigate the possible relationships between dietary habits and salivary biochemical properties in Chinese participants from different dietary background.

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