Publications by authors named "Shixiong Chen"

Recent advancements in feature selection (FS) optimization algorithms have influenced the field of epileptic seizure classification. However, integrating these optimization algorithms into machine learning (ML) models often creates time complexity, limiting their clinical deployment. To address this issue, we propose an innovative adaptive stepwise FS method tailored for epileptic seizure detection (ESD).

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Automatic detection of epilepsy plays a crucial role in diagnosing and treatment of patients, while most current methods rely on patient-specific models and have shown promising results, which is not suitable for clinical application, especially when new patient data are used for diagnosis in EEG epileptic seizure detection (ESD). Therefore, the proposed study introduces a novel hybrid deep learning approach consisting of a one-dimensional convolutional neural network (1D CNN), a Multi-Long Short-Term Memory Network (MLSTM) with a multi-attention layer (MAT) for patient-specific, cross-patient, and patient-independent seizure detection. The 1D CNN model extracts spatial features, while the MLSTM extracts temporal features from segmented EEG data.

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  • Radiotherapy effectively targets tumors through DNA damage and reactive oxygen species, but it also risks harming normal tissues and facing radiation resistance.
  • Nanotechnology-based radiotherapy offers a promising way to improve treatment precision and enhance tumor targeting by using nanoparticles to boost reactive oxygen species and support immune response.
  • The review discusses methods of improving radiotherapy through nanoparticles and highlights ongoing clinical trials, while exploring future opportunities for integrating these advancements into clinical practice.
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  • The study addresses the challenges neurologists face in analyzing multichannel EEG recordings for epileptic activities, proposing a computer-aided diagnosis system to minimize manual inspection.
  • Researchers introduce a novel short-time Fourier transform (STFT) algorithm utilizing taper functions to enhance spectrogram resolution, which improves the interpretability of EEG signals essential for seizure detection.
  • The developed Dilated Convolutional Squeeze and Excitation Networks (DCSENets) achieve a high average accuracy in patient-independent seizure classification while incorporating a visual explainer that enhances model interpretability, aiding neurologists in understanding diagnosis decisions.
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Microplastic remediation in aquatic bodies is essential for the entire ecosystem, but is challenging to achieve with a universal and efficient strategy. Here, we developed a sustainable and environmentally adaptable adsorbent through supramolecular self-assembly of chitin and cellulose. This biomass fibrous framework (Ct-Cel) showcases an excellent adsorption performance for polystyrene, polymethyl methacrylate, polypropylene, and polyethylene terephthalate.

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Objective: This study aimed to evaluate the impact of gene polymorphisms on clopidogrel metabolism and to use this analysis to inform treatment strategy for a population in southern Anhui of China.

Methods: The research was conducted from 2019 to 2022, aincluding 430 patients from the Wuhu Hospital, affiliated with East China Normal University who were candidates for clopidogrel therapy. Genes influencing clopidogrel's absorption and metabolism were analyzed to guide treatment.

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The issue of bacterial drug resistance has remained unresolved, and in recent years, biomimetic nanostructured surfaces inspired by nature have garnered significant attention due to their bactericidal properties demonstrated through mechanical mechanisms. This article reviewed the main research progress in the field of nanostructured mechanical bactericidal surfaces, including various preparation methods for nanostructured surfaces with mechanical bactericidal properties, as well as the basic mechanisms and related physical models of the interaction between bacteria and nanostructured surfaces. In addition, the application of nanostructured surfaces in biomedicine was introduced.

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  • Identifying the seizure occurrence period (SOP) in EEG recordings is critical for accurate seizure diagnosis, but current systems mainly differentiate between ictal and interictal states, limiting their clinical use due to reliance on labeled data.
  • This study presents an unsupervised learning framework called 1D-CasCAE that analyzes EEG segments, focusing on learning patterns from non-seizure segments to improve detection of seizure (ictal) segments without needing labeled data.
  • Experimental results show that the 1D-CasCAE outperforms existing methods in detecting anomalies in EEG recordings, achieving high scores in sensitivity, specificity, and precision, making it a promising tool for clinical applications to reduce the need for manual EEG analysis by neurologists.*
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  • Auditory Brainstem Response (ABR) is a method that measures how the brainstem responds to sound, particularly useful for diagnosing hearing loss and diseases by analyzing specific waves, especially Wave V latency.
  • Traditional methods for analyzing these waves are labor-intensive and time-consuming for clinicians, prompting the development of automated techniques, although these come with their own limitations.
  • The study presents a new deep learning model called ABR-Attention that effectively extracts Wave V latency, achieving a high accuracy of 96.76% while reducing clinician workload, offering a promising tool for more efficient auditory diagnostics.
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The property of being stubborn and degradation resistant makes nanoplastic (NP) pollution a long-standing remaining challenge. Here, we apply a designed top-down strategy to leverage the natural hierarchical structure of waste crayfish shells with exposed functional groups for efficient NP capture. The crayfish shell-based organic skeleton with improved flexibility, strength (14.

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  • Epilepsy is a neurological disorder marked by dangerous seizures, which are monitored using EEG signals; accurate detection relies on recognizing key EEG features.
  • This study introduces an Advanced Multi-View Deep Feature Learning (AMV-DFL) framework that uses machine learning to enhance EEG feature detection through traditional and deep learning methods.
  • Experimental results show that AMV-DFL outperforms other existing models by improving classification accuracy, aiding clinicians in identifying crucial EEG features and potentially discovering new biomarkers for epilepsy management.
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  • - The study presents an Explainable Artificial Intelligence (XAI)-based framework for detecting epileptic seizures through automated analysis of EEG signals, addressing the complexities involved in such tasks.
  • - The proposed system includes modules for feature engineering, seizure detection, and decision-making, leveraging techniques like the Butterworth filter and Dual-Tree Complex Wavelet Transform to enhance signal clarity and extract meaningful features.
  • - Using Stacking Ensemble Classifiers, the method achieves a 2% improvement in detection accuracy and integrates the SHAP technique to make predictions more interpretable for clinicians, all while ensuring the security of EEG data through blockchain technology.
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Long-term electrocardiogram (ECG) monitoring is an important and widely-used technique in the clinic that helps with the diagnosis of possible diseases that cannot be detected in a short time monitoring. However, the clinically used electrode needs conductive gel to reduce the impedance between the skin and the electrodes, which easily causes the possibility of allergy. Moreover, as the conductive gel becomes dry, the signal's quality will decrease accordingly.

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In the design of prosthetic hand fingers, achieving human-like movement while meeting anthropomorphic demands such as appearance, size, and lightweight is quite challenging. Human finger movement involves two distinct motion characters during natural reach-and-grasp tasks: consistency in the reaching stage and adaptability in the grasping stage. The former one enhances grasp stability and reduces control complexity; the latter one promotes the adaptability of finger to various objects.

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With the widespread application of 5G technology, there has been a significant surge in wireless video service demand and video traffic due to the proliferation of smart terminal devices and multimedia applications. However, the complexity of terminal devices, heterogeneous transmission channels, and the rapid growth of video traffic present new challenges for wireless network-based video applications. Although scalable video coding technology effectively improves video transmission efficiency in complex networks, traditional cellular base stations may struggle to handle video transmissions for all users simultaneously, particularly in large-scale networks.

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. Attention-deficit/hyperactivity disorder (ADHD) is the most common neurodevelopmental disorder in adolescents that can seriously impair a person's attention function, cognitive processes, and learning ability. Currently, clinicians primarily diagnose patients based on the subjective assessments of the Diagnostic and Statistical Manual of Mental Disorders-5, which can lead to delayed diagnosis of ADHD and even misdiagnosis due to low diagnostic efficiency and lack of well-trained diagnostic experts.

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In cross-border transactions, the transmission and processing of logistics information directly affect the trading experience and efficiency. The use of Internet of Things (IoT) technology can make this process more intelligent, efficient, and secure. However, most traditional IoT logistics systems are provided by a single logistics company.

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Two-photon polymerization based direct laser writing (DLW) is an emerging micronano 3D fabrication technology wherein two-photon initiators (TPIs) are a key component in photoresists. Upon exposure to a femtosecond laser, TPIs can trigger the polymerization reaction, leading to the solidification of photoresists. In other words, TPIs directly determine the rate of polymerization, physicochemical properties of polymers, and even the photolithography feature size.

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Congenital Muscular Torticollis (CMT) is a neuromuscular disease in children, which leads to exacerbation of postural deformity and neck muscle dysfunction with age. Towards facilitating functional assessment of neuromuscular disease in children, topographic electromyography (EMG) maps enabled by flexible and stretchable surface EMG (sEMG) electrode arrays are used to evaluate the neck myoelectric activities in this study. Customed flexible and stretchable sEMG electrode arrays with 84 electrodes were utilized to record sEMG in all subjects during neck motion tasks.

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Long-term epidermal electrophysiological (EP) monitoring is crucial for disease diagnosis and human-machine synergy. The human skin is covered with hair that grows at an average rate of 0.3 mm per day.

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Early detection and proper treatment of epilepsy is essential and meaningful to those who suffer from this disease. The adoption of deep learning (DL) techniques for automated epileptic seizure detection using electroencephalography (EEG) signals has shown great potential in making the most appropriate and fast medical decisions. However, DL algorithms have high computational complexity and suffer low accuracy with imbalanced medical data in multi seizure-classification task.

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Introduction: Electromyogram-based pattern recognition (EMG-PR) has been widely considered an essentially intuitive control method for multifunctional upper limb prostheses. A crucial aspect of the scheme is the EMG signal recording duration (SRD) from which requisite motor tasks are characterized per time, impacting the system's overall performance. For instance, lengthy SRD inevitably introduces fatigue (that alters the muscle contraction patterns of specific limb motions) and may incur high computational costs in building the motion intent decoder, resulting in inadequate prosthetic control and controller delay in practical usage.

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Neonatal hypoxic-ischemic encephalopathy (HIE) is a common disease that affects brain function in neonates. At present, mild hypothermia and hyperbaric oxygen therapy are the main methods for the treatment of neonatal HIE; however, they are independent of each other and cannot be combined for synchronous treatment, without monitoring of brain function-related physiological information. In addition, parameter setting of hyperbaric oxygen chamber and mild hypothermia mattress relies on the experience of the medical practitioner, and the parameters remain unchanged throughout the medical process.

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Article Synopsis
  • * This study introduced a new method using swept tones to capture high-resolution phase data of stimulus frequency OAEs (SFOAEs) in humans, revealing important differences in phase behavior among those with normal hearing versus those with hearing loss.
  • * The findings suggest that measuring OAE phase gradients can enhance the detection of cochlear function issues, advocating for their inclusion in standard auditory health assessments.
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