Analysis of the patient-sharing network in hypertension management: a retrospective study in China.

Objective: To explore the robustness of the patient-sharing network and validate the association between strength and persistence of physicians' relationships in China.

Design, Setting And Participants: We conducted a patient-sharing network analysis to describe the persistence of patient-sharing relationships and logistic regression to analyse factors associating with the persistence of patient-sharing relationships in the Yinzhou Health Information System from 1 January 2010 to 31 December 2018; all outpatient records that had a hypertension diagnosis were included in this study.

Outcome Measures: The persistence ratio was defined as the proportion of the patient-sharing relationships in a given year that continued to exist in the following year, the 1-, 2- and 3-year persistence to test the robustness of the findings.

A Theoretical Study on the Catalytic Mechanisms of Ethane to Aromatics over Zn-FAU Zeolite.

The ethane-to-aromatics (ETA) mechanisms on Zn-modified FAU have been studied by a two-layer ONIOM approach. The ETA process contains two stages: ethane to ethylene (ethane dehydrogenation) and ethylene to aromatics (ethylene aromatization). Two models, (Zn-O-Zn) and (O-Zn-O), are used as catalytic centers in the Zn-FAU.

An ultra-stable prelithiated Sn anode for sulfide-based all-solid-state Li batteries.

A prelithiated Sn (LiSn) anode was developed for sulfide-based all-solid-state Li batteries (ASSLBs), demonstrating high compatibility with LiPSCl sulfide electrolyte. The LiSn|NCM811 cell achieved 163 mA h g capacity (0.1C) and 91% retention after 650 cycles (1C).

Effect of music intervention on dental anxiety and fear: A bibliometric analysis of RCTs from 2004 to 2024.

Background: Dental treatments, especially invasive procedures, often induce anxiety and fear, impacting future treatment adherence. Music intervention, a non-pharmacological approach, has shown promise in reducing anxiety and enhancing well-being, but further research is needed to explore its application in dental settings and the influence of factors like music type, duration, and volume.

Objective: To assess the effects of music interventions on dental anxiety and fear, analyze research trends, and identify knowledge gaps through a bibliometric analysis of randomized controlled trials.

Application of double-sleeve endotracheal tube in infection control for icu patients: a randomized controlled trial.

Background: Poor oral hygiene in patients with tracheal intubation will increase the occurrence of dental plaque and mucosal inflammation, resulting in oral barrier dysfunction. This study aimed to design and evaluate a novel double-lumen endotracheal tube (DETT) and explore its role in infection control, particularly its effects on the oral microenvironment and ventilator-associated pneumonia (VAP).

Methods: This was a prospective, non-blinded, randomized parallel-controlled trial conducted from July 2024 to September 2024.

Electrochemical reduction-induced oxygen vacancies and in-situ selenization strategies synergistically construct high-performance supercapacitors.

Supercapacitors encounter difficulties in terms of slow kinetics. The development of supercapacitors with fast reaction kinetics is a significant challenge. This work presents the synthesis ofnickel foam (NF)-supported CoMn layered double hydroxides (CoMn-LDH) and CoSe composites (O-CoMn-LDH@CoSe/NF) were synthesized using electrochemical reduction-induced oxygen vacancy (O) and in situ selenization strategies.

Bone Marrow Aspirate Concentrate Combined With an Appropriate Carrier Effectively Promotes Bone-Tendon Interface Healing in a Rabbit Model of Chronic Rotator Cuff Tear.

Background: The efficacy of bone marrow aspirate concentrate (BMAC) in promoting bone-tendon interface (BTI) healing without any carriers remains a subject of debate.

Purpose: To evaluate BMAC effects with different carriers on tendon regeneration in a rabbit model of chronic rotator cuff tear.

Study Design: Controlled laboratory study.

Effects of different humeral stem lengths on stem alignment and proximal stress shielding in reverse total shoulder arthroplasty.

Background: Few comparative studies on the correlation between stem length, stem alignment, and/or stress shielding have been conducted in reverse total shoulder arthroplasty (rTSA). This study aimed to investigate the effects of different humeral stem lengths on stem alignment and proximal stress shielding after rTSA.

Methods: A total of 320 patients who underwent primary rTSA from October 2010 to May 2020 with at least 2 years of follow-up (mean follow-up: 32.

Dual-Stage Stacking Machine Learning Method Considering Virtual Sample Generation for the Prediction of ZIF-8' BET Specific Surface Area with Experimental Validation.

The widespread application of metal-organic frameworks (MOFs) in wastewater and gas treatment has created an increasing demand for accurate and rapid assessment of their BET specific surface area. However, experimental methods for acquiring sufficient statistical data are often costly and time-consuming. Therefore, this study proposes a dual-stage stacking model with Gaussian mixture model-virtual sample generation (GMM-VSG) technology for the BET specific surface area prediction.

Mfsd2a suppresses colorectal cancer progression and liver metastasis via the S100A14/STAT3 axis.

Background: Colorectal cancer (CRC) exhibits a high incidence globally, with the liver being the most common site of distant metastasis. At the time of diagnosis, 20-30% of CRC patients already present with liver metastases. Colorectal liver metastasis (CRLM) is a major cause of mortality among CRC patients.

Comparative analysis of clinical characteristics of symptomatic pituitary adenomas in elderly patients: a consecutive series of 114 patients.

Background: Pituitary adenomas (PAs) present with clinical features such as neuroendocrine abnormalities and mass effects, common in the general morbidity population. However, in elderly patients, the disease progression renders some clinical features difficult to detect and identify in time. Consequently, elderly patients with PAs are often not identified and receive sufficient intervention on time to achieve a satisfactory outcome.

Dynamic and sustainable supramolecular biolubrication coatings through nanoarchitectonics with dynamic BN bonding.

Biological lubricating materials play a crucial role in normal human activities due to their extremely low coefficients of friction (COFs). However, synthetic friction materials typically exhibit higher friction coefficients and wear rates compared to natural lubricating materials. To address this issue, we propose a novel lubrication strategy: reducing the friction coefficient of synthetic lubricating materials through supramolecular dynamic exchange.

Optimization control for mean square synchronization of stochastic semi-Markov jump neural networks with non-fragile hidden information and actuator saturation.

This paper studies the asynchronous output feedback control and H synchronization problems for a class of continuous-time stochastic hidden semi-Markov jump neural networks (SMJNNs) affected by actuator saturation. Initially, a novel neural networks (NNs) model is constructed, incorporating semi-Markov process (SMP), hidden information, and Brownian motion to accurately simulate the complexity and uncertainty of real-world environments. Secondly, acknowledging system mode mismatches and the need for robust anti-interference capabilities, a non-fragile controller based on hidden information is proposed.

One-Step Multiplex RT-PCR Method for Detection of Melon Viruses.

This study presents a one-step multiplex reverse transcription polymerase chain reaction (RT-PCR) method for the simultaneous detection of multiple viruses affecting melon crops. Viruses such as (WMV), (CMV), (ZYMV), (SqMV), (TMV), (PRSV), and (MYSV) pose a great threat to melons. The mixed infection of these viruses is the most common observation in the melon-growing fields.

Effect of structure and interaction on physicochemical properties of new [Emim][BFX] complex anion ionic liquids studied by quantum chemistry.

Context: One of the key challenges in the industrial application of ionic liquids (ILs) is their extreme characteristics, such as viscosity, glass transition temperatures, and conductivity. Understanding the relationship between ILs structure and physicochemical property is a crucial aspect of the directed design of ILs with good properties, which is a prerequisite for their successful implementation in industrial processes. In this work, high-level quantum-chemical research with for four pairs ionic liquids, [Emim][X] and [Emim][BFX] (X = CHSO, EtSO, HSO, Tos), was performed, to analyze the stable structure, interionic interaction, and charge transfer and provide a new insight into the property variances at the molecular level.

Cost-effectiveness analysis of atezolizumab plus bevacizumab and chemotherapy for the treatment of metastatic, persistent, or recurrent cervical cancer (BEATcc).

Background: The addition of atezolizumab to bevacizumab plus platinum regimen has demonstrated notable improvements in treating metastatic, persistent, or recurrent cervical cancer, but its cost-effectiveness requires further investigation. From a US payer perspective, we aimed to evaluate the cost-effectiveness of atezolizumab plus bevacizumab and chemotherapy vs. standard chemotherapy as a first-line treatment for metastatic, persistent, or recurrent cervical cancer.

Synthesis and Performance Evaluation of Metallocene Polyalphaolefins (mPAO) Base Oil with Anti-Friction and Anti-Wear Properties.

Anti-wear and anti-oxidation abilities are two key properties of lubricants that play a crucial role in ensuring long-term stable equipment operation. In this study, we aimed to develop a base oil with good anti-oxidation and anti-wear properties for use under extreme pressure. The as-prepared metallocene polyalphaolefin (mPAO) was chemically modified using the trifluoromethanesulfonic acid (TfOH) catalysis through an alkylating reaction with triphenyl phosphorothioate (TPPT).

Cost-effectiveness analysis of selpercatinib versus chemotherapy and pembrolizumab in the first-line treatment of rearranged during transfection fusion-positive non-small cell lung cancer in the United States.

Background: Although selpercatinib has shown clinical benefits for rearranged during transfection (RET) fusion-positive non-small cell lung cancer (NSCLC), its cost-effectiveness requires further evaluation.

Aim: This study aimed to evaluate the cost-effectiveness of selpercatinib versus chemotherapy and pembrolizumab in the first-line treatment of RET fusion-positive NSCLC from the perspective of the United States (US) payer.

Method: A partitioned survival model was developed based on data from the LIBRETTO-431 trial.

Stereoselective synthetic approach toward β-trifluoromethyl vinyl ethers and diethers reaction of ()-1,2-dichloro-3,3,3-trifluoroprop-1-ene with phenols.

A convenient method for synthesizing β-trifluoromethyl vinyl ethers and diethers through the base-mediated C-O coupling of ()-1,2-dichloro-3,3,3-trifluoroprop-1-ene and phenols has been developed. Remarkably, the present process shows perfect regioselective and stereoselective yield of the / isomers for β-trifluoromethyl vinyl ethers with high efficiency. Additionally, β-trifluoromethyl vinyl diethers with identical/diverse phenoxy groups were also obtained and the regulation of the product configuration was achieved.

Iodophor-catalyzed sulfenylation of indoles with sulfonyl hydrazides for the synthesis of 3-sulfenylindoles.

An iodophor-catalyzed sulfenylation of indoles using sulfonyl hydrazides as sulfur source to synthesize 3-sulfenylindoles in aqueous phase has been achieved. Notably, iodophor as catalyst and solvent is inexpensive, commercially available and no innocuous to the environment. The method is also easy to operate.

Targeting TNFR2 for cancer immunotherapy: recent advances and future directions.

Cancer is the leading cause of death worldwide, accounting for nearly 10 million deaths every year. Immune checkpoint blockade approaches have changed the therapeutic landscape for many tumor types. However, current immune checkpoint inhibitors PD-1 or CTLA-4 are far from satisfactory, due to high immune-related adverse event incident (up to 60%) and the inefficiency in cases of "cold" tumor microenvironment.

Se vacancies and interface engineering modulated bifunctionality prussian blue analogue derivatives for overall water splitting.

It is a challenging task to design and synthesize stable, and high-performance non-precious metals bifunctional catalysts for water-splitting. Herein, the coupling between Se vacancy and interface engineering is highlighted to synthesize a unique CoFeSe hollow nanocubes structure on MXene-modified nickel foam (NF) by in-situ phase transition from bifunctionality prussian blue analogue (PBA) derivatives (V-CoFeSe@MXene/NF). DFT theory reveals that the Se vacancy and interface engineering modulate the surface electronic structure and optimize the surface adsorption energy of the intermediates.

Cost-effectiveness of Azvudine for High-risk Outpatients with Mild-to-moderate Coronavirus Disease 2019 in China.

Purpose: This study aimed to evaluate the cost-effectiveness of Azvudine for the treatment of mild-to-moderate coronavirus disease 2019 in high-risk outpatients using real-world data and relevant references.

Methods: In the decision-tree model, 2 cohorts were organized in a single center to compare the cost-effectiveness between the Azvudine plus symptomatic treatment group and the symptomatic treatment group. We calculated the cost and mortality rate for both groups.