Synthesis, structure, oxygen evolution reaction (OER) and visible-light assisted organic reaction studies on AMTeBO (A = Ba and Pb; M = Mg, Zn, Co, Ni, Cu, and Fe).

Compounds with the general formula AMTeBO (A = Ba and Pb; M = Mg, Zn, Co, Ni, Cu, and Fe) have been synthesised solid-state techniques and characterised. The structure exhibits MBO layers connected by TeO octahedra giving rise to a three-dimensional structure with voids, where Ba ions reside. Substitution of Mg by transition elements (M = Co, Ni, and Cu) in BaMgTeBO and (BaPb)MgTeBO gives rise to interesting colored compounds.

Cellulose nanocrystals/cellulose nanofibrils-combined astaxanthin nanoemulsion for reinforcement of targeted tumor delivery of gastric cancer cells.

Nanoemulsion based nanomaterial (NE) was carried out in the present study to evaluate the efficacy and its antitumor potential of the gastric cancer cells. NE was prepared with astaxanthin/alpha-tocopherol- cellulose nanocrystals/cellulose nanofibrils based nanoemulsions for gastric cancer treatment. The cytotoxic potential was tested against cancer cells and evaluated in terms of its cell proliferation, migration, and cellular uptake by the standard methods.

Plant bioactive compounds driven microRNAs (miRNAs): A potential source and novel strategy targeting gene and cancer therapeutics.

Irrespective of medical technology improvements, cancer ranks among the leading causes of mortality worldwide. Although numerous cures and treatments exist, creating alternative cancer therapies with fewer adverse side effects is vital. Since ancient times, plant bioactive compounds have already been used as a remedy to heal cancer.

Clinico-Radiological Perspectives of Pycnodysostosis - A Rare Case Series.

Pycnodysostosis is an inherited autosomal recessive disorder characterized by dysplasia of the skeletal system. It occurs in any human races with no disparity in gender or age predilection. The disease is diagnosed at a young age owing to the frequent fragile bone fractures.

Assessment of Knowledge on Dietary Management of Chronic Kidney Disease Among Patients Undergoing Hemodialysis at a Tertiary Care Hospital in South India: A Cross-Sectional Analytical Study.

Background This cross-sectional analytical study aimed to assess the level of knowledge on dietary management of chronic kidney disease (CKD) among patients undergoing hemodialysis in a tertiary care hospital in Puducherry, South India. Methodology The study was conducted among 86 inpatients diagnosed with CKD and undergoing hemodialysis in the dialysis unit. They were selected by simple random sampling.

Defect engineered ternary metal spinel-type Ni-Fe-Co oxide as bifunctional electrocatalyst for overall electrochemical water splitting.

Transition metal spinel oxides were engineered with active elements as bifunctional water splitting electrocatalysts to deliver superior intrinsic activity, stability, and improved conductivity to support green hydrogen production. In this study, we reported the ternary metal Ni-Fe-Co spinel oxide electrocatalysts prepared by defect engineering strategy with rich and deficient Na ions, termed NFCO-Na and NFCO, which suggest the formation of defects with Na forming tensile strain. The Na-rich NiFeCoO spinel oxide reveals lattice expansion, resulting in the formation of a defective crystal structure, suggesting higher electrocatalytic active sites.

Structurally engineered highly efficient electrocatalytic performance of 3-dimensional Mo/Ni chalcogenides for boosting overall water splitting performance.

Hydrogen production from water splitting combined with renewable electricity can provide a viable solution to the energy crisis. A novel MoS/NiS/NiS heterostructure is designed as a bifunctional electrocatalyst by facile hydrothermal method to demonstrate excellent electrocatalytic performance towards overall water splitting applications. MoS/NiS/NiS heterostructure necessitates a low overpotential of 81 mV and 210 mV to attain a current density of 10 mA cm during the hydrogen evolution reaction (HER) and oxygen evolution reaction (OER), respectively.

Immobilization of hydrochar in cellulose beads for eradicating paracetamol from synthetic and sewage water.

Sodium carboxymethyl cellulose polymer was used as a support matrix in immobilizing activated hydrochar derived from bamboo using hydrothermal carbonization. The structural and textural morphology of the beads were studied using FTIR, XRD, SEM/EDS, BET and TGA. Activated hydrochar showed a rough surface with irregular spherical shaped structure.

Site suitability analysis for locating construction and demolition waste transfer station: an Indian case study.

Construction and Demolition Waste Management (CDWM) includes collecting, transporting, processing, and disposing construction and demolition (C&D) waste, where collection and transportation of bulky and voluminous C&D waste contribute significantly to economic and environmental impacts. Transfer station (TS) being a link between various waste management (WM) facilities plays a significant role in collection and transportation of waste. Thus, locating TS at suitable site can help in reducing the overall impacts.

Prescribing patterns and pharmacoeconomic analysis of antihypertensive drugs in South Indian population: A cross-sectional study.

Background: Global evidence-based recommendations for hypertension management are periodically updated, and ensuring adherence to the guidelines is imperative. Furthermore, the current high prevalence of hypertension effectuates a high health-care cost.

Purpose: To evaluate the prescribing patterns of antihypertensive drugs and other factors affecting blood pressure (BP) with the objective of assessing the proportion of patients achieving the target BP and to perform a pharmacoeconomic analysis in a South Indian population.

Assessment of Readiness Toward Flipped Learning Among Novice Nursing Students on Fundamental Nursing Care in Puducherry, South India.

Background This study aimed to assess the readiness toward flipped learning (FL) among novice nursing students in fundamental nursing care in Puducherry, South India.  Methodology A cross-sectional descriptive study was conducted among 176 first-year B.Sc.

Two-step fabrication of cellulose embedded FeO/Fe composite beads as catalyst in degradation of sulfamethoxazole in floating bed reactor.

In this study, magnetite particles were successfully embedded in sodium carboxymethyl cellulose as beads using FeCl as the cross-linker in two step-method and it was used as a Fenton-like catalyst to degrade sulfamethoxazole in aqueous solution. The surface morphology and functional groups influence of the Na-CMC magnetic beads was studied using FTIR and SEM analysis. The nature of synthesized iron oxide particles was confirmed as magnetite using XRD diffraction.

Mobile technology acceptance among undergraduate nursing students instructed by blended learning at selected educational institutions in South India.

Background: Mobile phones have become a widely accepted learning mode due to the impact of COVID-19. This study explores the mobile technology acceptance, among nursing students at selected educational institutions in South India.

Materials And Methods: Quantitative cross-sectional descriptive design.

Preparedness of primary & secondary care health facilities for the management of non-communicable diseases in tribal population across 12 districts in India.

Background And Objectives: Non-communicable diseases (NCDs) are highly prevalent in the tribal populations; however, there are limited data regarding health system preparedness to tackle NCDs among these populations. We estimated the availability of human resources, equipment, drugs, services and knowledge of doctors for NCD management in the selected tribal districts in India.

Methods: A cross-sectional survey was conducted in 12 districts (one from each State) with at least 50 per cent tribal population in Andaman and Nicobar Islands, Himachal Pradesh, Madhya Pradesh, Odisha and eight northeastern States.

Non-communicable diseases as a major contributor to deaths in 12 tribal districts in India.

Background & Objectives: Non-communicable diseases (NCDs) are the leading cause of death in India. Although studies have reported a high prevalence of NCD in tribal populations, there are limited data pertaining mortality due to NCDs. Therefore, in this study we estimated the proportion of deaths due to NCDs among 15 yr and older age group in tribal districts in India.

Nanocubic copper cobaltite for methyl orange degradation through photocatalytic process.

In this study, cubic spinel structured CuCoO (Copper cobaltite) nanospheres were fabricated by thermal decomposition method. The visible light degradation of organic contaminant methyl orange (MO) was focused in this study using the synthesized pure CuO, CoO and CuCoO with different weight ratios of raw materials (90:10, 75:25 and 50:50). It could be well realized that after the characterization techniques, the synthesized CuCoO materials resembled cubic spinel structure as confirmed by X-ray diffraction (XRD) investigation.

A case report of moderate COVID 19 patient managed through integrative approach (Siddha and conventional medicine).

Introduction: COVID 19 is a rapidly spreading disease with high mortality and morbidity all over the world which is caused by SARS-COV-2. Siddha system has various formulations with antiviral properties. The study is aimed at evaluating the efficacy of Siddha integrated with conventional medicine for effective management of COVID 19.

Caspase-mediated cleavage of miRNA processing proteins Drosha, DGCR8, Dicer, and TRBP2 in heat-shocked cells and its inhibition by HSP70 overexpression.

Cells respond to stress through adaptive mechanisms that limit cellular damage and prevent cell death. MicroRNAs act as regulators of stress responses and stress can impact the functioning of miRNA biogenesis pathways. We were interested in the effect that severe proteotoxic stress capable of inducing apoptosis may have on miRNA biogenesis and the impact of the molecular chaperone protein HSP70 under these conditions.

Dynactin 1 negatively regulates HIV-1 infection by sequestering the host cofactor CLIP170.

Many viruses directly engage and require the dynein-dynactin motor-adaptor complex in order to transport along microtubules (MTs) to the nucleus and initiate infection. HIV type 1 (HIV-1) exploits dynein, the dynein adaptor BICD2, and core dynactin subunits but unlike several other viruses, does not require dynactin-1 (DCTN1). The underlying reason for HIV-1's variant dynein engagement strategy and independence from DCTN1 remains unknown.

Quantum chemical calculation, performance of selective antimicrobial activity using molecular docking analysis, RDG and experimental (FT-IR, FT-Raman) investigation of 4-[{2-[3-(4-chlorophenyl)-5-(4-propan-2-yl) phenyl)-4, 5-dihydro- 1H- pyrazol-1-yl]-4-oxo-1, 3- thiazol-5(4H)-ylidene} methyl] benzonitrile.

The research received a great deal of worldwide attention due to the nature of interpretation before the experimental process. Based on the systematic process the structure of thiazole -pyrazole compound 4-[{2-[3-(4-chlorophenyl)-5-(4-propan-2-yl) phenyl)-4, 5-dihydro- 1H- pyrazol-1-yl]-4-oxo-1, 3- thiazol-5(4H)-ylidene} methyl] benzonitrile [CPTBN] was investigated. In the first level, the spectral statistics on experimental FT-IR and FT- Raman was reported.

Clinical outcomes among COVID-19 patients managed with modern and traditional Siddha medicine - A retrospective cohort study.

Background: (KSK) is a Siddha polyherbal decoction recommended by the Ministry of AYUSH and the Tamil Nadu government to prevent and manage COVID-19 in India.

Objectives: We aimed to determine the outcome of integrated therapy for COVID-19 using KSK in virologic clearance and length of hospital stay.

Materials And Methods: It was a single-centre, retrospective cohort study.

Synthesis of nanohydroxyapatite/collagen-loaded fucoidan-based composite hydrogel for drug delivery to gastrointestinal cancer cells.

The present study aims to evaluate the synthesis of nanohydroxyapatite/collagen-loaded fucoidan-based composite hydrogel and characterized its physico-chemical properties for targeted drug delivery to gastrointestinal cancer cells. The nanomaterial is fabricated and characterized as small spherical nanosheets with a high thermal stability by using Fourier transform infrared (FTIR) analysis, X-ray diffraction (XRD), Thermogravimetric analysis (TGA), UV-vis spectrophotometry (UV-vis), scanning electron microscopy (SEM) and transmission electron microscopy (TEM). in vitro cytotoxicity, BrdU cell proliferation, and scratch assays demonstrate that the nanohydroxyapatite/collagen-loaded fucoidan-based nanomaterial exhibits non-toxicity and increases cell proliferation and migration.