[Nonsyndromic sensorineural deafness--analysis of etiology in relatives].

We present the results of complex clinical examination of children affected with sensorineural hearing loss. The siblings (minimum two) were born from unaffected parents and came from twelve families. Molecular studies confirmed genetic background of hearing loss in 6 families and enabled identification of GJB2 mutations in investigated probants.

[Analysis of hearing impairment causes in molecular diagnosis of deafness].

Deafness is one of the most frequent congenital hearing impairments. Knowledge of its causes will result in elimination of risk factors and applying prophylactic activities. It is recognized that about 40% of hearing impairments have genetic origin and 80% of these are autosomal recessive.

High frequency of GJB2 gene mutations in Polish patients with prelingual nonsyndromic deafness.

We report an analysis of 102 unrelated Polish patients with profound prelingual deafness for mutations in the GJB2 gene (OMIM #220290). Mutations were found in 41/102 (40%) subjects. Among mutated alleles, 35delG was prevalent and present in 88%.

[Searching new diagnostic and rehabilitation techniques in small deaf children].

In the generally accepted model of the diagnosis and rehabilitation in small deaf children, the main concern of various specialists is focused on the development of speech and hearing abilities. In our approach, we propose another perspective, in which the deaf child is not seen as an object of the speech education and where the specialists concentrate on the child as a whole--with his various emotional needs and psychical traits. According to that way of seeing the deaf child, we organized the diagnostic-rehabilitation courses for small deaf children and their parents (9 children aged 1.

[Elaboration of a model for the rehabilitation of children with severe hearing loss].

New diagnostic model of rehabilitation in young deaf children was performed. Study presents 33 patients with a profound hearing impairment examined by means of "day-time hospital".

[Selected problems in the rehabilitation of young children with severe hearing loss].

The aim of the work was an analysis of the causes of difficulties in the rehabilitation of children with profound hearing loss. A theoretical basis of this analysis is the assumption that rehabilitation effects are determined by factors related to the system of care of the deaf child, diagnostic possibilities, and psychophysical properties of the child. The reported analysis was carried out in a material of 232 children aged up to 3 years, treated at the Audiology Outpatient Clinic of the Institute.

[Evaluation of hearing in children with an isolated cleft of the secondary palate].

Examinations of hearing and middle ears has been estimated in 101 children at the age from 2 to 13 years with cleft defect of the face, as a isolated cleft of secondary palate. All the children were under treatment at the Surgery Clinic for Children and Jouth of the Institut for Mother and Child. Hearing impairment of conductive type has been found in 53% (percent) of the children taken for treatment and inflammation of the middle ear in 64%.