The see-saw effect of neuroactive steroids and endocrine disrupting compounds on maternal mental health status.

Background: Antepartum depression, a non-psychotic mood disturbance occurring during pregnancy, is influenced by hormonal fluctuations and environmental endocrine disruptors. Despite its association with adverse postpartum outcomes, it has been studied to a limited extent. Hence, this study aims to investigate the association of neuroactive steroids, endocrine-disrupting compounds, and nutritional status of pregnant women with the manifestations of antepartum depressive symptoms.

Material surface conjugated with fibroblast growth factor-2 for pluripotent stem cell culture and differentiation.

Fibroblast growth factor-2 (FGF-2) is a critical molecule for sustaining the pluripotency of human pluripotent stem (PS) cells. However, FGF-2 is extremely unstable and cannot be stored long periods at room temperature. Therefore, the following FGF-2-conjugated cell culture materials were developed to stabilize FGF-2: FGF-2-conjugated polyvinyl alcohol (PVAI-C-FGF) hydrogels and FGF-2-conjugated carboxymethyl cellulose-coated (CMC-C-FGF) dishes.

Enhancer zeste homolog 2 (EZH2) targeting by small interfering RNA (siRNA); recent advances and prospect.

Enhancer of zeste homolog 2 (EZH2) serves as the enzymatic catalytic subunit of the polycomb repressive complex 2 (PRC2), which is capable of modifying the expression of downstream target genes through the trimethylation of Lys-27 on histone 3 (H3K27me3). In addition to its role in H3K27me3 modification, EZH2 may influence gene expression through alternative mechanisms. The involvement of EZH2 in cellular processes such as proliferation, apoptosis, and senescence has been established.

A Smile for the Future: Nanotechnology Impact on Aesthetics, Durability, and Functionality in Prosthodontics.

Nanotechnology is revolutionizing prosthodontics by enhancing the aesthetics, durability, and functionality of dental restorations. Nanomaterials can mimic the natural appearance of teeth with unprecedented precision, resulting in lifelike and visually appealing prosthetics. Their superior strength and wear resistance extend the longevity of restorations, reducing the need for replacements and lowering costs.

Synthesis, Photophysical Properties and Systematic Evaluation of New Class Fluorescein Based Derivative with Organic Solvents: Spectroscopic and Density Functional Theory Methods for Optoelectronic Applications.

In this report the photophysical property of newly synthesized fluorescein based derivative 2-(5-((2,4-dichlorophenyl)diazenyl)-6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid has studied by spectroscopic and theoretical that is by Density Functional Theory technique. The structural and functional group of the synthesized molecule was confirmed by nuclear magnetic resonance and fourier transform infrared spectroscopy technique, and from the result so far obtained has been confirmed that molecule has a stable structure and confirmed the presence the functional groups present in the sample. The optical properties of the molecule are studied using the spectroscopic technique and it has revealed the solute-solvent interaction behaviour of the molecule and it has been observed that the bathochromic shift was of about 5 nm, from the fluorescence measurement it has revealed that the emission has been observed at green region and from the power spectra it has been confirmed the same.

Fungal Planet description sheets: 1697-1780.

Novel species of fungi described in this study include those from various countries as follows: , from accumulated snow sediment sample. , on leaf spots of . , on submerged decaying wood in sea water, on , as endophyte from healthy leaves of .

Unlocking the Photoluminescence Potential of Tabebuia Rosea Dyes: A Novel Natural Source of Broadband Visible Spectral Fluorescence for OLED Technologies.

This investigation delves into the extraction of polyphenols from the flowers of Tabebuia rosea using a basic maceration approach with acetone, ethanol, and methanol as solvents. The spectroscopic analysis of the dye obtained confirms the existence of functional groups in the polyphenol extract. The study also explores optoelectronic, fluorescence, and photometric characteristics associated with polyphenols.

Light Harvesting Materials: A Study on Förster Resonance Energy Transfer and Optoelectronic Properties of Potential Nerium oleander Flowers.

The present study focused on extracting the anthocyanin dyes in ethanol, acidic ethanol, methanol, and acidic methanol solvents from Nerium oleander flowers by a simple maceration extraction process. FTIR spectroscopy and vibrational studies have confirmed the existence of polyphenolic groups in 2-phenyl chromenylium (anthocyanin) dyes. The optoelectronic results show the least direct bandgap (2.

Model Organoids: Integrated Frameworks for the Next Frontier of Healthcare Advancements.

The morphogenetic events leading to tissue formation can be recapitulated using organoids, which allows studying new diseases and modelling personalized medicines. In this review, culture systems comparable to human organs are presented, these organoids are created from pluripotent stem cells or adult stem cells. The efficient and reproducible models of human tissues are discussed for biobanking, precision medicine and basic research.

Electrochemical Applications Reveal Enhanced Photocatalytic Performance of TiO -Doped ZnS Nanocomposites.

The titanium dioxide (TiO) nanoparticles were prepared by hydrothermal methods at ambient temperature. Based on XRD analysis, the average crystallite size of pure TiO nanoparticles and those doped with ZnS was calculated to be 58 and 54 nm, respectively. At an angle of 25.

Temperature-dependent Rotational Dynamics of a 3-(benzo[d]Thiazol-2-yl)-7-diethylamino)-2 H-chromen-2-one non-polar Probe in n-pentanol, n-nonanol, and n-decanol Solvents.

Rotational dynamics of non-polar probe 3-(benzo[d]thiazol-2-yl)-7-(diethylamino)-2 H-chromen-2-one (3BT7D2H-one) and in n-pentanol, n-nonanol, and n-decanol alcohol solvents is studied using steady-state fluorescence depolarization and time-correlated single photon counting technique with varying temperature. Experimental observations indicate that 3BT7D2H-one rotates slowly in n-decanol solvent compared to other chosen solvents. Rotational motion is analyzed using the Stoke 's-Einstein-Debye (SED) model.

Influence of Viscosity and Temperature on Rotational Dynamics of 3-(1H-benzo[d]Imidazol-2-yl)-7-(Diethyl Amino)-2H-chromen-2-one (Polar Laser dye) in Highly Viscous Solvent: Low and High Viscous Range.

Temperature-dependent rotational dynamics of 3-(1 H-benzo[d]imidazol-2-yl)-7-(diethyl amino)-2 H-chromen-2-one (3HBI-7D-2HChromen-2-one) has been studied in highly viscous glycerol solvent. Over the entire studied temperature range rotational reorientation time values vary linearly with temperature. Experimental obtained rotational results are analyzed using hydrodynamic and quasi-hydrodynamic models over the entire temperature range as well as low and high viscous range.

Temperature-Dependent Rotational Dynamics of a Polar Probe in Non-Polar Aprotic Solvents: Interplay of Solvent Viscosity and Size Effect.

Rotational dynamics of 3-(benzo[d]thiazol-2-yl)-7-(diethylamino)-2 H-chromen-2-one (3BT7D2H-one) probe in non-polar aprotic 1,4 dioxane, toluene and cyclohexane solvents of different and comparable viscosity are studied with varying temperature using steady-state and fluorescence depolarization technique. The experimental reorientation time is compared with the hydrodynamic Stoke's-Einstein-Debye(SED). The experimentally measured rotational reorientation times are higher in 1,4 dioxane attributed to its solvent viscosity.

Effect of Temperature on Rotational Dynamics of 3BT7D2H-one in Acetone and Ethyl Acetate Solvents.

The rotational dynamics of 3-(benzo[d]thiazol-2-yl)-7-(diethylamino)-2 H-chromen-2-one (3BT7D2H-one) in two non-polar solvents acetone and ethyl acetate have been studied with varying temperatures. The rotational dynamics follow follows the Stoke's-Einstein-Debye (SED) model in ethyl acetate solvent but shows deviation in acetone solvent when temperature is increased. Quasi-hydrodynamic models Gierer and Wirtz (GW) model and Dote-Kivelson Schwartz (DKS) is studied in a qualitatively way.

Biological synthesis of silver nanoparticles using Senna auriculata flower extract for antibacterial activities.

In this study, biological synthesis of silver nanoparticles (AgNPs) using Senna auriculata flower extract for antibacterial activities was reported. The silver spectra compared to the plant extract show a rightward shift in AgNP peaks, indicating successful nanoparticle formation. The absorption band at 302 nm and the disappearance or shift of other peaks further confirm the synthesis.

Effects of ECM protein-coated surfaces on the generation of retinal pigment epithelium cells differentiated from human pluripotent stem cells.

Retinal degeneration diseases, such as age-related macular degeneration (AMD) and retinitis pigmentosa (RP), initially manifest as dysfunction or death of the retinal pigment epithelium (RPE). Subretinal transplantation of human pluripotent stem cell (hPSC)-derived RPE cells has emerged as a potential therapy for retinal degeneration. However, RPE cells differentiated from hPSCs using current protocols are xeno-containing and are rarely applied in clinical trials.

Temperature-Dependent Rotational Dynamics of Non-Polar Solute in Non-Polar Solvents: Influence of Boundary Conditions.

Rotational dynamics of 3-(benzo[d]thiazol-2-yl)-7-(diethylamino)-2H-chromen-2-one (3BT7D2H-one) non-polar solute in non-polar solvents has been studied by varying temperature to find out how hydrodynamic friction is influenced by solute-size ratio. It has been observed that the rotational dynamics of 3BT7D2H-one follow the Stoke's-Einstein-Debye (SED) model in an n-hexane solvent and it follows the Gierer and Wirtz (GW) model in an n-decane solvent. The probable reason is due to the solute-solvent size ratio which influences boundary conditions parameters and consequently on rotational dynamics of solute.

Seasonal distribution and upsurge of respiratory viruses among indigenous tribes with ILI and SARI in a far-flung Car Nicobar Island.

Background: Respiratory viral illnesses among children are a prominent cause of morbidity and mortality in the developing world. The aim of this study is to understand the seasonal pattern and surge of respiratory viruses among the Nicobarese tribe.

Methods: Respiratory specimens were collected from both ARI and SARI cases attended the BJR district hospital in Car Nicobar Island, India, between 2021 and 2022.

Enriched characteristics of poultry collagen over other sources of collagen and its extraction methods: A review.

Collagen is the most abundant protein in animals and is extensively studied for its structural and thermal stability, biocompatibility, and healing properties which enables them to be widely applied in various fields. Collagen extracted from poultry sources have shown improved structural stability and reduced risk of triggering allergic responses and transmitting animal diseases onto humans. Furthermore, poultry collagen is widely accepted by consumers of diverse beliefs in comparison to collagen extracted from bovine and porcine sources.

Silver sulphide nanoparticles (AgSNPs) synthesized using Phyllanthus emblica fruit extract for enhanced antibacterial and antioxidant properties.

In this study, silver sulfide nanoparticles (AgSNP's) were successfully produced by using fruit extracts of Phyllanthus emblica. UV-vis, FTIR, XRD with SEM and EDX techniques were used for the synthesis process and for characterization of the resulting nanostructures. According to the findings, the fabricated nanostructure had a monoclinic crystal structure, measuring 44 nm in grain size, and its strain was 1.

Anthocyanins of Delonix Regia Floral Petals: A Novel Approach on Fluorescence Enhancement, Forster Resonance Energy Transfer Mechanism and Photostability Studies for Optoelectronic Applications.

In this work, we focused on extracting the anthocyanin dye in acetone, butanol, ethanol, and water solvents from Delonix regia flowers by a simple maceration extraction process. The identification of functional group analysis, vibrational studies, energy transfer mechanisms, optoelectronic properties, photostability studies, FRET-assisted potential light emissions and photometric properties of the anthocyanin dyes are successively investigated. FTIR spectroscopy and vibrational studies have confirmed the existence of polyphenolic groups in 2-phenyl chromenylium (anthocyanin) dyes.

Author Response.

Vijayakumar M, Selvam V, Renuka MK, Rajagopalan RE. Author Response. Indian J Crit Care Med 2024;28(5):512.

Author Response.

Vijayakumar M, Selvam V, Renuka MK, Rajagopalan RE. Author Response. Indian J Crit Care Med 2024;28(5):515.