Mango Leaves ()-Derived Highly Florescent Green Graphene Quantum Dot Nanoprobes for Enhanced On-Off Dual Detection of Cholesterol and Fe Ions Based on Molecular Logic Operation.

In the present study, we have engineered a molecular logic gate system employing both Fe ions and cholesterol as bioanalytes for innovative detection strategies. We utilized a green-synthesis method employing the mango leaves extract to create fluorescent graphene quantum dots termed "mGQDs". Through techniques like HR-TEM, i.

Physical characterization and bioavailability assessment of 5-fluorouracil-based nanostructured lipid carrier (NLC): In vitro drug release, Hemolysis, and permeability modulation.

5-Fluorouracil (5-FU) is an anticancer agent belonging to BCS Class III that exhibits poor release characteristics and low retention in the biological system. The main objective of this investigation was to develop a drug delivery system, i.e.

Clinical and bacteriological profile of abdominal surgical site infections in an Indian Hospital.

This study was carried out to assess the clinical and bacterial profiles of abdominal surgery site infections in a tertiary care hospital.Samples recovered from infected wounds at abdominal surgery sites were processed using highly advanced microbiological procedures. To process these samples, the most recently accepted standard CLSI guidelines were used.

Incidence of Surgical Site Infections and Surgical Antimicrobial Prophylaxis in JNMC, Bhagalpur, India.

Background: Surgery site infections (SSIs) are infections that arise in surgery for an operative wound infection surveillance within 30 days of surgery or 90 days after implant installation. JNMC, Bhagalpur, India, intended to look at the pre- and postoperative use of antibiotics.

Methods: Four hundred twelve patient charts were analyzed for four months in JNMC, Bhagalpur, India as part of a hospital-based cross-section study.

Identifying the Burden and Predictors of Diabetes Distress among Adult Type 2 Diabetes Mellitus Patients.

Background: Diabetes is a psychologically challenging medical condition. Diabetes distress (DD) refers to the unique, often hidden emotional burdens and worries that the patient experiences when managing diabetes.

Objective: The objective of the study was to find the burden and identify the predictors of DD in adult Type 2 diabetes mellitus (T2DM) patients.

Luminescence properties and exciton dynamics of core-multi-shell semiconductor quantum dots leading to QLEDs.

In this study, we grew CdSe core quantum dots (QDs) along with CdSe/ZnS/ZnS and CdSe/CdS/CdS core-multi-shell semiconductor QDs via successive ionic layer adsorption and reaction. The effects of the shell layers on the optical properties and exciton dynamics of the QDs were examined using steady-state and time-resolved measurements together with transient absorption (TA). The photoluminescence (PL) intensity and quantum yield (QY) of the synthesized QDs were enhanced by shell growth.

AB corroles: Fluorescence signaling systems for sensing fluoride ions.

Four free base corroles, 1-4, AB, (where A = nitrophenyl, and B = pentafluorophenyl, 2, 6-difluoro, 3, 4, 5-trifluoro and 4-carboxymethylphenyl group) have been synthesized, characterized and demonstrated as excellent chemosensor for the detection of fluoride ions selectively in toluene solution. The reported corroles shows highest quantum yield in free base form of porphyrinoid systems so far. All these corrole, 1-4, have the excellent ability to sense fluoride ion.

Facile Synthesis of Semiconducting Ultrathin Layer of Molybdenum Disulfide.

In this paper, we have reported a simple and efficient method for the synthesis of uniform, highly conducting single or few layer molybdenum disulfide (MoS2) on large scale. Scanning Electron Microscopy (SEM) and High Resolution Transmission Electron Microscopy (HRTEM) have been used for the confirmation of mono or few layered nature of the as-synthesized MoS2 sheets. X-ray Photoelectron Spectroscopy (XPS), X-Ray Diffraction (XRD) and Raman Spectroscopy have also been used to study the elemental, phase, and molecular composition of the sample.

Tunable single and double emission semiconductor nanocrystal quantum dots: a multianalyte sensor.

We have prepared stable colloidal CdTe and CdTe/ZnS core-shell quantum dots (QDs) using hot injection chemical route. The developed CdTe QDs emit tunable single and dual photoluminescence (PL) bands, originating from the direct band edge and the surface state of QDs, as evident by the steady-state and time-resolved spectroscopy. The developed CdTe and CdTe/ZnS QDs act as optical sensors for the detection of metal ions (e.

Investigation of biocompatible and protein sensitive highly luminescent quantum dots/nanocrystals of CdSe, CdSe/ZnS and CdSe/CdS.

The size and shape dependent semiconductor quantum dots (0D nanoparticles) with color tunability demonstrating significant influence in a biological system and considered as ideal probes. Here, a non-coordinated colloidal approach was used for the synthesis of CdSe, CdSe/ZnS and CdSe/CdS core-shell quantum dots (QDs) of 3-4nm. The synthesized nanocrystals show a high crystallinity, examined by X-ray diffraction (XRD) and high-resolution electron microscopy (HRTEM).

Controlling the last known cluster of Ebola virus disease - Liberia, January-February 2015.

As one of the three West African countries highly affected by the 2014-2015 Ebola virus disease (Ebola) epidemic, Liberia reported approximately 10,000 cases. The Ebola epidemic in Liberia was marked by intense urban transmission, multiple community outbreaks with source cases occurring in patients coming from the urban areas, and outbreaks in health care facilities (HCFs). This report, based on data from routine case investigations and contact tracing, describes efforts to stop the last known chain of Ebola transmission in Liberia.

Curcumin loaded pH-sensitive nanoparticles for the treatment of colon cancer.

The investigation was aimed at designing pH-sensitive, polymeric nanoparticles of curcumin, a natural anti-cancer agent, for the treatment of colon cancer. The objective was to enhance the bioavailability of curcumin, simultaneously reducing the required dose through selective targeting to colon. Eudragit S100 was chosen to aid targeting since the polymer dissolves at colonic pH to result in selective colonic release of the entrapped drug.

Communicable disease outbreak detection by using supplementary tools to conventional surveillance methods under Integrated Disease Surveillance Project (IDSP), India.

Communicable disease control relies on effective response systems and effective response systems rely on effective disease surveillance. Surveillance is first step towards prevention. In addition to conventional routine indicator based surveillance system, countries must develop additional tools in terms of supplementary surveillance system for providing information on early detection of outbreaks in India so that a timely and an appropriate action can be taken.