Two-Dimensional MXenes: Innovative Materials for Efficient Thermal Management and Safety Solutions.

MXenes, a class of 2-dimensional transition metal carbides and nitrides, have garnered important attention due to their remarkable electrical and thermal conductivity, high photothermal conversion efficiency, and multifunctionality. This review explores the potential of MXene materials in various thermal applications, including thermal energy storage, heat dissipation in electronic devices, and the mitigation of electromagnetic interference in wearable technologies. Recent advancements in MXene composites, such as MXene/bacterial cellulose aerogel films and MXene/polymer composites, have demonstrated enhanced performance in phase change thermal storage and electromagnetic interference shielding, underscoring their versatility and effectiveness.

PPDPF promotes esophageal squamous cell carcinoma progression by blocking PCCA binding to PCCB and inhibiting methionine catabolism.

While metabolic reprogramming and remodeling of tumor microenvironment play important roles in the development of esophageal squamous cell carcinoma (ESCC), the mechanisms remain unclear. In this study, we found that pancreatic progenitor cell differentiation and proliferation factor (PPDPF) is upregulated in ESCC and its expression level is associated with lymph node metastasis. PPDPF was found to promote tumorigenesis, lymph node metastasis and distal metastasis of ESCC cells.

Enhanced Degradation of Oxytetracycline Antibiotic Under Visible Light over BiWO Coupled with Carbon Quantum Dots Derived from Waste Biomass.

Improving the photogenerated carrier separation efficiency of individual semiconductor materials has always been a key challenge in photocatalysis. In this study, we synthesized a novel photocatalytic material, N-CQDs/UBWO, in situ by combining nitrogen-doped carbon quantum dots (N-CQDs) derived from discarded corn stover with ultrathin BiWO nanosheets (UBWO). Detailed characterization indicates that the random distribution of N-CQDs on the UBWO surface increases the specific surface area of UBWO, which is beneficial for the adsorption and degradation of oxytetracycline (OTC).

Ultra-strong and solvent-resistant lignin-based non-isocyanate polyurethane adhesives: One-pot strategy toward versatile bonding.

Isocyanate-free polyurethane adhesives have attracted considerable attention as a promising environmentally friendly alternative. However, their progress has been hindered by insufficient bonding performance and weak solvent resistance, as well as the laborious synthesis processes involved. Herein, we successfully synthesized a high-performance lignin-based non-isocyanate adhesives (LNIPUs-G) through a one-pot strategy that combines the polycondensation of carbonate groups with polyether amines and aldehyde-amine chemistry.

Synergistic Contribution of the Strain and Magnetic Field in Ferromagnetic NiMnIn Heusler Alloy Films for the Hydrogen Evolution Reaction.

The external field-assisted hydrogen evolution reaction (HER), beyond modifying electrocatalysts themselves, has garnered significant research attention. However, achieving synergy between multiple fields to enhance the HER performance remains challenging and is not well-explored. Here, NiMnIn Heusler alloy thin films are fabricated using pulsed laser deposition on flexional Cu substrates.

Crystalline potassium boryl dithiolate and diselenolate.

Both the B-S and S-S bonds of 1,2,4,3,5-trithiadiborolane 1 could be cleaved by potassium graphite (KC) to give the first isolable boryl dithiolate DmpB(SK)3, whereas the reduction of 1,2,4-triselena-3,5-diborolane 2 with KC afforded the boryl diselenolate DmpB(SeK)(SeSeK) 4, showcasing the unprecedented structural authentication of ligand substituted diselenolate.

Facile Synthesis of Fluorescent Carbon Quantum Dots with High Product Yield Using a Solid-Phase Strategy.

The liquid-phase method is the most commonly utilized strategy for synthesizing fluorescent carbon quantum dots (CQDs). However, the liquid-phase synthesis of CQDs faces challenges such as low yield, complex purification, and the use of toxic solvents, which limit large-scale production and practical applications. In this study, fluorescent CQDs with a high product yield of 78% were synthesized using glucose as a carbon source through a green and facile one-step solid-phase approach, without solvents or post-treatment.

Near-Infrared-II-Activated Transition Metal(II)-Coordinated Ligand Radical Primes Robust Anticancer Immunity.

Photoactivatable metallodrugs combining tumor cell eradication and immune stimulation hold immense promise for targeted cancer therapy. However, limitations such as oxygen dependence, narrow visible light responsiveness, and poor immunogenicity hinder their efficacy in deep solid tumors with hypoxic and immunosuppressive microenvironments. Herein, we present a novel design strategy for transition metal(II)-coordinated ligand radicals exhibiting intense near-infrared-II (NIR-II) absorption, unique endoplasmic reticulum-targeting capability, and oxygen-independent photothermal performance, effectively addressing these constraints.

A rat model for microimplant-assisted rapid palatal expansion.

Background: Microimplant-assisted rapid palatal expansion (MARPE) has been widely used to correct maxillary transverse deficiency. To gain valuable insights into the biological processes and mechanisms involved in palatal suture expansion and develop approaches to reduce relapse rates, researchers have turned to animal models. However, no small-animal models are currently available for MARPE.

A deep eutectic solvent with bifunctional acid sites treatment to upgrade a bamboo kraft pulp into a cellulose-acetate grade dissolving pulp.

Valorization of non-wood pulp, such as bamboo bleached kraft pulp into high-purity cellulose acetate (CA)-grade dissolving pulp is crucial but challenging in China. Herein, a series of metal salt-based deep eutectic solvents (MSDESs) involving various ZnCl-urea (U), ZnCl-glycerol (G), and ZnCl-lactic acid (LA) are comparatively investigated for this purpose. Thanks to the bifunctional acid sites of Lewis acid ZnCl and Brønsted acid LA, the ZnCl-LA MSDES has the highest acidity (2.

MT1G promotes iron autophagy and inhibits the function of gastric cancer cell lines by intervening in GPX4/SQSTM1.

Gastric cancer (GC) is the fifth most common cancer and the third most common cause of cancer death globally, with high invasiveness, high recurrence rate, and poor prognosis. Multiple studies have shown that Metallothionein-1G (MT1G) is closely associated with oxidative stress, ferroptosis, and autophagy. However, the role and potential mechanisms of MT1G in GC have not been fully elucidated.

Potassium ion channel modulation at cancer-neural interface enhances neuronal excitability in epileptogenic glioblastoma multiforme.

The central nervous system (CNS) is increasingly recognized as a critical modulator in the oncogenesis of glioblastoma multiforme (GBM), with interactions between cancer and local neuronal circuits frequently leading to epilepsy; however, the relative contributions of these factors remain unclear. Here, we report a coordinated intratumor shift among distinct cancer subtypes within progenitor-like families of epileptic GBM patients, revealing an accumulation of oligodendrocyte progenitor (OPC)-like subpopulations at the cancer-neuron interface along with heightened electrical signaling activity in the surrounding neuronal networks. The OPC-like cells associated with epilepsy express KCND2, which encodes the voltage-gated K channel K4.

Protraction of a mandibular second molar into the adjacent atrophic first-molar extraction site with ridge-split technique through clear aligners: A case report.

This case report describes the successful orthodontic management of a 25-year-old female patient presenting with Class II Division 2 malocclusion, moderate maxillary anterior crowding, and a missing mandibular left first molar. Treatment plan involved extraction of two maxillary first premolars to address crowding and protraction of two mandibular left molars, combined with the strategic use of mini-implants for precise tooth movement control. Ridge-split surgery was adopted to manage alveolar ridge resorption in the edentulous area.

Graph domain adaptation-based framework for gene expression enhancement and cell type identification in large-scale spatially resolved transcriptomics.

Spatially resolved transcriptomics (SRT) technologies facilitate gene expression profiling with spatial resolution in a naïve state. Nevertheless, current SRT technologies exhibit limitations, manifesting as either low transcript detection sensitivity or restricted gene throughput. These constraints result in diminished precision and coverage in gene measurement.

Research progress of tumor-associated macrophages in immune checkpoint inhibitor tolerance in colorectal cancer.

The relevant mechanism of tumor-associated macrophages (TAMs) in the treatment of colorectal cancer patients with immune checkpoint inhibitors (ICIs) is discussed, and the application prospects of TAMs in reversing the treatment tolerance of ICIs are discussed to provide a reference for related studies. As a class of drugs widely used in clinical tumor immunotherapy, ICIs can act on regulatory molecules on cells that play an inhibitory role-immune checkpoints-and kill tumors in the form of an immune response by activating a variety of immune cells in the immune system. The sensitivity of patients with different types of colorectal cancer to ICI treatment varies greatly.

Stereodivergent atom transfer radical addition of α-functionalized alkyl iodides to alkynes: a strategy for selective synthesis of both - and -iodoalkenes.

The geometrical control of atom transfer radical addition (ATRA) reactions to alkynes poses significant challenges. Herein, we present a uniform solution by developing a stereodivergent synthetic method for both isomers of the resulting alkene products, starting from the same materials. The synthesis of the thermodynamically more stable isomer utilizes the strategy of uphill catalysis while the accumulation of the less stable isomer is facilitated by a manganese-catalyzed iodo-abstraction/radical rebound process, taking advantage of its reversibility.

Facilitating Ion Storage and Transport Pathways by In Situ Constructing 1D Carbon Nanotube Electric Bridges between 2D MXene Interlayers.

Multiple van der Waals (vdW) gaps invoke abundant opportunities for contriving artificial architectures and tailoring desired properties via the intercalation route beyond the reach of conventional concepts. Intriguingly, the electrochemical intercalation strategy can precisely and reversibly tune the intercalation stage of charged functional species. This study presents a valid structural editing protocol facilitated by electrochemical intercalation to engineer MXene interlayers, ultimately incorporating in situ constructed carbon nanotube (CNT) electric bridges for enhanced ion storage and transport pathways.

Biomechanical analysis of the effect of Class II traction configurations and aligner overtreatment on molar distalization: a finite-element study.

Objective: This study aimed to evaluate the biomechanical effects of aligner overtreatment on molar distalization using clear aligners.

Methods: Various models were created and integrated into finite-element software. Six distinct study models were devised for analysis.

Synthesis, Crystal Structure and Antifungal Activity of ()-1-(4-Methylbenzylidene)-4-(3-Isopropylphenyl) Thiosemicarbazone: Quantum Chemical and Experimental Studies.

A novel ()-1-(4-methylbenzylidene)-4-(3-isopropylphenyl) thiosemicarbazone was synthesized in a one-pot four-step synthetic route. Fourier transform infrared spectroscopy (FTIR), H and C nuclear magnetic resonances (NMR), single-crystal X-ray diffraction, and UV-visible absorption spectroscopy were utilized to confirm the successful preparation of the title compound. Single-crystal data indicated that the intramolecular hydrogen bond N(3)-H(3)···N(1) and intermolecular hydrogen bond N(2)-H(2)···S(1) (1 - x, 1 - y, 1 - z) existed in the crystal structure and packing of the title compound.

Cantilever-aided bodily protraction of a mandibular molar with clear aligner: A finite element analysis.

Objective: To analyse the biomechanics of molar protraction through clear aligner therapy (CAT) with and without a buccal cantilever.

Methods: Models were composed of mandible, lower dentition, periodontal ligaments, attachments, a buccal cantilever, and clear aligner. Four groups were designed: (1) control (aligner only), (2) aligner+buccal cantilever with buccal class II traction, (3) aligner+buccal cantilever with buccal class II and lingual class II tractions, (4) aligner+buccal cantilever with buccal horizontal traction named buccal class I, buccal class II, and lingual class II tractions.