Development of peptone-based serum-free media to support Vero CCL-81 cell proliferation and optimize SARS-CoV2 viral production.

Background: Developing an optimal media for Vero cell lines is crucial as it directly influences cell survival, proliferation, and virus production. The use of serum in cell culture raises safety concerns in biological production. The United States Food and Drug Administration (FDA) and the European Medicines Agency have implemented stricter regulations on the use of animal-derived components in commercial protein manufacturing to ensure patient safety.

Patterns of kidney diseases diagnosed by kidney biopsy and the impact of the COVID-19 pandemic in Yogyakarta, Indonesia: A single-center study.

Background: Glomerular diseases rank third among the causes of chronic kidney disease worldwide and in Indonesia, and its burden continues to increase, especially regarding the sociodemographic index. Kidney biopsy remains the gold standard for the diagnosis and classification of glomerular diseases. It is crucial for developing treatment plans, determining the degree of histologic changes, and identifying disease relapse.

Interventions to improve pharmacists' competency in chronic disease management: a systematic review of randomized controlled trials.

Introduction: Effective chronic disease management (CDM) is vital for addressing chronic disease challenges. Given the importance of ensuring pharmacists' competence in CDM, interventions targeting knowledge, skills, and attitudes are essential. Therefore, a comprehensive and up-to-date study is needed to analyze these interventions' effect and potential development.

Determinants of the quality of life of mother with children with disability: A systematic review.

Mothers who care for children with disabilities experience various problems that affect their quality of life. The objective of this study was to identify the factors that influence the quality of life of mothers with disabilities children. A systematic review was conducted using data from six prominent electronic databases.

Influence of stressful life events in postpartum mothers on the incidence of postpartum depression.

The main objective of the study was to explore and document the influence of the stressful life events experienced by postpartum mothers on the incidence of postpartum depression. A systematic review of literature was performed to examine prior research. All major databases including Google Scholar, Scopus, and Web of Science were used.

Prevention and management of hypertension in middle-aged and elderly through screening and education (Pre-post intervention).

Maintaining quality of life and physical health in the elderly is crucial for their overall well-being. Hypertension, a prevalent condition among the elderly in Indonesia, requires targeted interventions to mitigate its impact. A quasi-experimental pre-post intervention study was conducted in Bandar Lor, Kediri City, Indonesia, involving 106 elderly participants.

Examining behavioural determinants among caregivers of children with attention-deficit hyperactivity disorder using the human action process framework.

This study assessed the caregiver's adaptability and appropriate parenting behaviour towards children with Attention-Deficit Hyperactivity Disorder (ADHD) based on their background and mental health using the theory of Health Action Process Approach (HAPA). The study recruited 24 caregivers who completed surveys at four-weekly intervals. A moderated mediation model was used to examine the mediating effects of intentions, actions, and caregivers' resilience.

Immunomodulatory effect of propolis spp. in mice infected with .

Background: Toxoplasmosis is a zoonotic disease caused by . Infection with virulent strains of induces excessive production of pro-inflammatory cytokines and increases fatality. Propolis has potential as an anti-inflammatory and immunomodulator.

Implementation of the Digital Health Approach to Support Learning for Health Students Based on Bloom's Taxonomy: A Systematic Review.

Objectives: Health students' ability to utilize technology effectively is vital for improving the quality of future healthcare services. Relevant digital health education must be comprehensively integrated into training programs, continuing professional development activities, and school curricula to keep them current. This study investigated the most effective digital health approaches to enhance health students' cognitive, affective, and psychomotor skills, thereby preparing them for the workforce.

Molecular detection of spp. among wild rats in Surabaya, East Java, Indonesia.

Background: Humans and animals who have an acute case of diarrhea can be infected with spp. Within the category of water-borne disease, it is a zoonotic disease. The zoonotic disease is among the several pathogens carried by wild rats ( spp.

Classical swine fever: Unveiling the complexity through a multifaceted approach.

Classical swine fever (CSF), sometimes referred to as hog cholera, is a highly contagious, virally based, systemic illness that affects both domestic and wild pigs. The virus known as classical swine fever virus (CSFV) is a member of the Flaviviridae family, specifically the genus Pestivirus. This disease is thought to be endemic in many Asian countries that produce pork as well as in several countries in Central and South America, the Caribbean, and elsewhere.

Factors Associated with Health-Seeking Behavior in Indonesia: Evidence from the Indonesian Family Life Survey 2014.

: Health-seeking behavior is a critical determinant of health outcomes, particularly in countries like Indonesia. Given the increasing burden of noncommunicable diseases, understanding the factors that influence health-seeking behavior in this context is essential for developing more accessible and effective public health strategies. This study aimed to identify various factors associated with health-seeking behavior among patients with chronic diseases across Indonesia, especially in formal facilities.

Pharmacists perspectives on challenges and facilitators in initiating medications take-back program in Indonesia: A qualitative study.

Objective: The establishment of a medication take-back program is an important intervention to prevent the improper disposal of expired or unused household medications. However, such a program has not been established in Indonesia. A significant step in establishing the program is to gain a better understanding of pharmacists' perspectives on the associated challenges and facilitators.

Embracing leadership of local actors and community in disaster risk reduction of Yogyakarta.

Unlabelled: The Disaster Preparedness Village (Kampung Siaga Bencana or KSB) in Special Region of Yogyakarta Province (DIY) is a community that aims to increase community preparedness and resilience to disasters through collaboration between the local government, non-government organisations and the community. This research examines the sustainability factors of KSB, namely the role of local leadership and government collaboration in disaster risk reduction (DRR) efforts. The method used in this research is a qualitative method and Strength, Weakness, Opportunity and Threat (SWOT) analysis, then using a diamond model to visualise the role of local leadership and the role of government.

Eleven-Year Report of High Number of Diphtheria Cases in Children in East Java Province, Indonesia.

A high incidence of diphtheria cases in children in East Java province, Indonesia, has been observed since the beginning of this century. Despite many efforts, the outbreaks continue. This study aims to explain the high incidence of diphtheria in children in East Java province since 2013.

Protein characterization of an Indonesian isolate of foot and mouth disease virus inactivated with formaldehyde and binary ethylenimine.

Background And Aim: Foot-and-mouth disease (FMD) is a highly contagious viral disease of cloven-footed animals. It is a major threat to livestock production worldwide, causing significant economic losses. Inactivation of FMD virus (FMDV) is crucial for vaccine development and control of outbreaks.

Molecular detection of toxoplasmosis in wild rats using loop-mediated isothermal amplification assay.

Background And Aim: Toxoplasmosis is caused by the parasite . Cats are the only known hosts that excrete resistant oocysts. Wild rats serve as crucial reservoirs and intermediate hosts for survival and dissemination.

Interleukin-6 and Interleukin-10 as a Predictor of Mortality in Elderly with COVID-19.

Context: The age group at the most high risk for mortality due to SARS-CoV-2 infection was the elderly.

Aims: This study aims to analyze markers that can predict the severity and mortality of elderly COVID-19 patients.

Settings And Design: This study used a cohort retrospective design.

Inactivation of an Indonesian isolate of foot-and-mouth disease virus using formaldehyde.

Background And Aim: Foot-and-mouth disease (FMD) is a highly contagious viral disease that endangers livestock and the environment with significant economic consequences. This study aimed to validate the inactivation of the Indonesian isolate of foot-and-mouth disease virus (FMDV) with various formaldehyde concentration.

Materials And Methods: The experiment started with FMDV being adapted on BHK-21 cells until cytopathic effects (CPE) appeared.