Impact of selenium supplementation on antioxidant enzyme activity and liver gene expression in juvenile pangasius catfish (Pangasius pangasius).

This study examined the effect of dietary selenium (Se) fortification on growth efficiency, antioxidant status, and liver gene expression in juvenile pangasius catfish. Sodium selenite was incorporated into a basal diet at incremental levels of 0-2.0 mg Se/kg.

Exploring Acupuncture as an Adjunctive Therapy for Puberty Menorrhagia: A Case Report.

Background: Puberty menorrhagia, characterized by prolonged and excessive menstrual bleeding between menarche and 19 years of age, presents clinical challenges at adolescents and it is attributed to an immature hypothalamo-pituitary-ovarian axis, leading to sustained high estrogen levels and anovulation. This case report explores the efficacy of acupuncture as an adjunctive therapy for pubertal menorrhagia of a 16-year-old female with a history of irregular menstrual cycles and excessive bleeding for 41 days.

Methodology: Based on Traditional Chinese Medicine (TCM) tongue and pulse diagnostics of the patient, acupuncture needling at SP4 (Gongsun), PC 6 (Neiguan), KI 14 (Siman), SP 10 (Xuehai), LR 1 (Dadun), CV 6 (Qihai) was given once in a day for a month, each session lasting 20 min targeting to alleviate Liver blood stasis.

Smartphone usage and its association with stress-related bruxism, temporomandibular joint disorder among dental tutees - an analytical investigation.

Background: In recent times, smartphones have become a major part of our lives due to its various benefits such as easy accessibility of information, social connectivity, convenience, smaller size etc. Smartphone overuse can cause stress in a student which can invariably lead to clenching or grinding of teeth and temporomandibular disorder.

Objective: The aim of this study was to evaluate the association between smartphone use, stress due to over-usage, bruxism and temporomandibular disorders among dental students in a private dental institution in Chennai, India.

Statin-Induced Necrotizing Autoimmune Myopathy: Diagnosis and Treatment Approach.

The widespread use of statins for cardiovascular diseases has unveiled a new subset of inflammatory myopathy, immune-mediated necrotizing myopathy (IMNM). We describe below an unusual case of anti-3-hydroxy-3-methylglutaryl-coenzyme A reductase (anti-HMGCR) myopathy. A 64-year-old male individual with type 2 diabetes, hyperlipidemia, and coronary artery disease presented with progressive proximal muscle weakness and pain for 3 months.

Diagnosis and management of metabolic dysfunction- associated steatotic liver disease in South Asians- A clinical review.

Background: Metabolic dysfunction-associated steatotic liver disease (MASLD), previously termed as nonalcoholic fatty liver disease (NAFLD) is a hepatic manifestation of obesity and metabolic syndrome. It is mainly caused by insulin resistance. With the increased risk of visceral obesity in South Asians, the prevalence of MASLD is on the rise.

Low Haemoglobin is Inversely Associated with Disease Activity in Rheumatoid Arthritis: A Cross-Sectional Study from a Tertiary Care Hospital.

Aim: Extra-articular manifestations especially haematological abnormalities are common in Rheumatoid arthritis (RA). The aim is to study the haematological parameters and its correlation with disease severity and gender.

Methods: A cross-sectional study was conducted at a tertiary centre among 50 RA patients who attended the Rheumatology or General Medicine OPD from January 2020 to June 2021.

Temperature-dependent highly active LaCaMgAlO catalyst effect on carbon nanomaterial and hydrogen generation from polymethyl methacrylate plastic.

The increasing accumulation of waste polymethyl methacrylate (PMMA) plastics presents a significant environmental challenge, while the demand for renewable energy sources continues to rise. Thermochemical recycling is a prospective technique for converting waste plastics into high-value chemicals, both economically and environmentally. In this work, the catalytic pyrolysis of waste PMMA plastics over LaCaMgAlO nanosheets (NSs) catalyst is being investigated for its potential to produce hydrogen and carbon nanotubes (CNTs) in a two-stage fixed-bed reactor.

Prevalence of Migraine Headache among Patients with Allergic Rhinitis in a Tertiary Care Hospital, Puducherry.

Allergic rhinitis is one of the most common and undertreated diseases in the world. In recent times, there has been increased development of non-sinus headaches among patients with allergic rhinitis. Various common endogenous molecules such as nitric oxide, calcitonin gene-related peptide, and histamine have been implicated in the development of migraines, which leads to the development of migraines among allergic rhinitis patients.

A Retrospective Analysis of Urethroplasty and Medical Malpractice.

Objective: To review malpractice suits stemming from urethroplasty intervention, which is the standard of care for patients suffering from urethral strictures.

Methods: This retrospective study analyzed the LexisNexis and Westlaw databases between 1980 and 2024. Each database was queried with "urethroplasty" which yielded 48 cases and 20 jury verdicts/settlements in the LexisNexis database and 46 cases and 14 jury verdicts in the Westlaw database.

The 2024 British Society for Rheumatology guideline for management of systemic sclerosis.

This guideline was developed according to the British Society for Rheumatology Guidelines Protocol by a Guideline Development Group comprising healthcare professionals with expertise in SSc and people with lived experience, as well as patient organization representatives. It is an update of the previous 2015 SSc guideline. The recommendations were developed and agreed by the group and are underpinned by published evidence, assessed by systematic literature review and reinforced by collective expert opinion of the group.

The 2024 British Society for Rheumatology guideline for management of systemic sclerosis-executive summary.

This guideline was developed according to the British Society for Rheumatology Guidelines Protocol by a Guideline Development Group comprising healthcare professionals with expertise in SSc and people with lived experience, as well as patient organization representatives. It is an update of the previous 2015 SSc guideline. The recommendations were developed and agreed by the group and are underpinned by published evidence, assessed by systematic literature review and reinforced by collective expert opinion of the group.

ISCCM Position Statement: Management of Severe Dengue in Intensive Care Unit.

Unlabelled: Dengue is one of the commonest causes of undifferentiated acute febrile illness in India as well as South East Asia. Nearly two-fifths of the world population is at risk of infection, and nearly 96 million infections reported worldwide, it is a major cause of concern across the globe. The ISCCM leadership felt that there have been no new directives/guidelines except the MOH guidelines for the management of dengue fever since 2014.

Connected smart elevator systems for smart power and time saving.

Smart elevators provide substantial promise for time and energy management applications by utilizing cutting edge artificial intelligence and image processing technology. In order to improve operating efficiency, this project designs an elevator system that uses the YOLO model for object detection. Compared to traditional methods, our results show a 15% improvement in wait times and a 20% reduction in energy use.

Fabrication of SrTiO anchored rGO/g-CN photocatalyst for the removal of mixed dye from wastewater: dual photocatalytic mechanism.

A metal-free combination of rGO/g-CN-coupled SrTiO (SRN) ternary nanocomposite prepared via a wet impregnation method for UV-Vis light photocatalytic applications. Various physicochemical properties of the samples were investigated by several spectroscopic techniques including X-ray diffraction (XRD), FT-IR, Raman, field emission scanning electron microscopy with energy dispersive X-ray spectroscopy (FE-SEM-EDX), high-resolution transmission electron microscopy (HR-TEM), UV-Vis, photoluminescence (PL), X-ray photoelectron spectroscopy (XPS) and Brunauer-Emmett-Teller (BET) surface area analysis. The data suggest agglomerated SRT nanoparticles are dispersed and distributed throughout the surface of the rGO sheets and GCN nanostructures.

Prevalence of Dental Caries in Tamil Nadu State, India: A Comprehensive Umbrella Analysis.

Dental caries is a major public health concern among other oral diseases in most developing and industrialized countries, particularly in those nations where preventative programs have not yet been developed. Adults and the elderly population in Tamil Nadu also face significant challenges related to dental caries beyond children and adolescents. This systematic review examined the comprehensive epidemiology of dental caries in all age groups in Tamil Nadu.

Sustainable approach for the expulsion of metaldehyde: risk, interactions, and mitigation: a review.

All pests can be eliminated with the help of pesticides, which can be either natural or synthetic. Because of the excessive use of pesticides, it is harmful to both ecology and people's health. Pesticides are categorised according to several criteria: their chemical composition, method of action, effects, timing of use, source of manufacture, and formulations.

The diagnostic potentiality of the RNA aptamer against progesterone receptor isolated by crush and soak (CRUSOAK)-SELEX.

Aptamers are a class of molecular recognition elements that exhibit high binding affinity and specificity against their respective targets. In view of the many advantages aptamers harbor over their counterpart antibodies, we were impelled to isolate an RNA aptamer against progesterone receptor, particularly its DNA binding domain. A total of eight SELEX cycles were executed against the recombinant Progesterone Receptor DNA-binding domain (PR DBD).

Natural bio-waste-derived 3D N/O self-doped heteroatom honeycomb-like porous carbon with tuned huge surface area for high-performance supercapacitor.

Supercapacitor electrodes (SCs) of carbon-based materials with flexible structures and morphologies have demonstrated excellent electrical conductivity and chemical stability. Herein, a clean and cost-effective method for producing a 3D self-doped honeycomb-like carbonaceous material with KOH activation from bio-waste oyster shells (BWOSs) is described. A remarkable performance was achieved by the excellent hierarchical structured carbon (HSC-750), which has a large surface area and a reasonably high packing density.

Extraction and characterization of novel fibers from Tecoma stans Linn bark for use as reinforcement in polymer composites.

Embarking on a pioneering investigation, this study unravels the extraordinary qualities of Tecoma stans Fibers (TSFs), freshly harvested from the rachis, establishing them as prospective reinforcements for biocomposites. Delving into their intricate characteristics, TSFs exhibit a unique fusion of physical resilience, with a density of 1.81 ± 0.

Bimetal-organic frameworks derived redox-type composite materials for high-performance energy storage.

Electrodes and electroactive materials are crucial components in the development of supercapacitors due to their geometric properties. In this study, bimetal-organic frameworks (Bi-MOFs, ZIF-8@ZIF-67) were utilized as electrode materials for a high-performance hybrid supercapacitor (HSC) by designing a novel synthesis of metallic carbonate hydroxide/oxides. In particular, the Bi-MOFs function as a sacrificial precursor in the synthesis of hollow NiMn(CO)·0·.

Characteristics of hydrogen energy yield in steam gasification of coffee residues.

Coffee residues (CRs) were gasified using a laboratory-scale fluidized bed gasifier with an air/steam mixture as the carrier gas. The gasification was conducted at an equivalence ratio (ER) of 0.3, and different operation temperatures (700, 800, and 900 °C) and steam-to-biomass (S/B) ratios (0, 0.

Metal organic framework anchored onto biowaste mediated carbon material (rGO) for remediation of chromium (VI) by the photocatalytic process.

Groundwater contaminated with hexavalent chromium Cr(VI) causes serious health concerns for the ecosystem. In this study, a hybrid amino functionalized MOF@rGO nanocatalyst was produced by utilization of a biowaste mediated carbon material (reduced graphene oxide; rGO) and its surface was modified by in situ synthesis of a nanocrystalline, mixed ligand octahedral MOF containing iron metal and NH functional groups and the prepared composite was investigated for Cr (VI) removal. The photocatalytic degradation of Cr(VI) in aqueous solutions was carried out under UV irradiation.

Noncanonical assembly, neddylation and chimeric cullin-RING/RBR ubiquitylation by the 1.8 MDa CUL9 E3 ligase complex.

Ubiquitin ligation is typically executed by hallmark E3 catalytic domains. Two such domains, 'cullin-RING' and 'RBR', are individually found in several hundred human E3 ligases, and collaborate with E2 enzymes to catalyze ubiquitylation. However, the vertebrate-specific CUL9 complex with RBX1 (also called ROC1), of interest due to its tumor suppressive interaction with TP53, uniquely encompasses both cullin-RING and RBR domains.

ProTect: a hybrid deep learning model for proactive detection of cyberbullying on social media.

The emergence of social media has given rise to a variety of networking and communication opportunities, as well as the well-known issue of cyberbullying, which is continuously on the rise in the current world. Researchers have been actively addressing cyberbullying for a long time by applying machine learning and deep learning techniques. However, although these algorithms have performed well on artificial datasets, they do not provide similar results when applied to real-time datasets with high levels of noise and imbalance.