Publications by authors named "Popsy"
Objective: The aim of this study was to prepare solid lipid microparticles (SLM) with incorporated ofloxacin, suitable for oral delivery.
Methods: Ofloxacin-loaded SLM were prepared using stearic acid and chloroform as lipid matrix and Tween-80 as surfactant, by high shear homogenization technique and followed by lyophilization. The physiochemical characterization of SLMs were investigated by scanning electron microscopy, transmission electron microscopy, zeta potential, zone of inhibition, in-vitro study, ex-vivo study and stability study.