Simultaneously high gravimetric and volumetric methane uptake characteristics of the metal-organic framework NU-111.

We show that the MOF NU-111 exhibits equally high volumetric and gravimetric methane uptake values, both within ≈75% of the DOE targets at 300 K. Upon reducing the temperature to 270 K, the uptake increases to 0.5 g g(-1) and 284 cc(STP) per cc at 65 bar.

Ubc9 promotes invasion and metastasis of lung cancer cells.

Lung cancer is the leading cause of cancer-related mortality worldwide. The mortality is high mainly due to the lack of known effective screening procedures; there is a high tendency for early spread and systemic therapies do not cure metastatic disease. Thus, it is important to investigate the molecular mechanism(s) of lung cancer development and, specifically, to identify an effective method by which to inhibit the invasion and metastasis of lung cancer.

Temperature sensing using the bandgap-like effect in a selectively liquid-filled photonic crystal fiber.

A compact temperature sensor based on a selectively liquid-filled photonic crystal fiber (PCF) is proposed using controlled hole collapse in PCF post-processing. The first ring around the core is filled with liquid of higher refractive index than the matrix, while the outer rings of holes are filled with air. The bandgap (BG)-like effect of the high refractive index ring is analyzed.

Tetra-bromidobis(dicyclo-hexyl-phosphane-κP)digallium(Ga-Ga).

The title compound, a Ga(II) dimer, [Ga(2)Br(4)(C(12)H(23)P)(2)], was synthesized by reaction of GaBr(THF)(n) (THF is tetra-hydro-furan) with dicyclo-hexyl-phosphine in toluene. At 150 K the crystallographically centrosymmetric molecule exhibits disorder in which one of the two independent cyclo-hexyl groups is modelled over two sites in a 62 (1):38 (1) ratio. In d(6)-benzene solution, the compound exhibits virtual C(2h) symmetry as determined by (1)H NMR.

Temperature sensor based on surface plasmon resonance within selectively coated photonic crystal fiber.

We demonstrate a temperature sensor based on surface plasmon resonances supported by photonic crystal fibers (PCFs). Within the PCF, to enhance the sensitivity of the sensor, the air holes of the second layer are filled with a large thermo-optic coefficient liquid and some of those air holes are selectively coated with metal. Temperature variations will induce changes of coupling efficiencies between the fundamental core mode and the plasmonic mode, thus leading to different loss spectra that will be recorded.

Garlicin attenuates reperfusion no-reflow in a catheter-based porcine model of acute myocardial infarction.

Objective: To evaluate whether garlicin can attenuate reperfusion no-reflow in a catheter-based porcine model of acute myocardial infarction (AMI).

Methods: Twenty-two swine were used: six in a sham-operation group, and eight each in the control and garlicin groups. The distal part of the left anterior descending coronary artery (LAD) in the latter two groups was occluded by a dilated balloon for 2 hr, then reperfused for 3 hr.

[Submucosal tunneling endoscopic resection for submucosal tumor originating from the muscularis propria layer of the esophagus].

Tumors originating from the muscularis propria layer of esophagus are usually removed by thoracoscopic resection. With the introduction of new endoscopic therapeutic techniques, some of these tumors could be treated by endoscopic submucosal dissection (ESD). However, the above endoscopic methods are associated with a high risk of perforation and it is hard to close the perforation through the endoscopy.

[Effect of ERK1/2 signaling pathway on astragaloside IV protects H9c2 cells against H2O2-induced oxidative injury].

Objective: To investigate whether Astragaloside IV(AST) protects H9c2 cells against H2O2-induced oxidative injury partly through ERK1/2 signaling pathway.

Methods: H9c2 cells oxidative injury was induced by 200 tmol/L H2O2 for 6 hours to establish the H2O2-induced injury model of H9c2 cells. The viability of H9c2 cells was detected using MTf method.

Adaptive kernel independent component analysis and UV spectrometry applied to characterize the procedure for processing prepared rhubarb roots.

By determination of the number of absorptive chemical components (ACCs) in mixtures using median absolute deviation (MAD) analysis and extraction of spectral profiles of ACCs using kernel independent component analysis (KICA), an adaptive KICA (AKICA) algorithm was proposed. The proposed AKICA algorithm was used to characterize the procedure for processing prepared rhubarb roots by resolution of the measured mixed raw UV spectra of the rhubarb samples that were collected at different steaming intervals. The results show that the spectral features of ACCs in the mixtures can be directly estimated without chemical and physical pre-separation and other prior information.

[Extraction of spectral information of additives from activated manganese dioxide products using adaptive kernel independent component analysis].

The additives were abstracted from the manganese dioxide products with four kinds of organic solvents, ether, acetone, chloroform and toluene. The extracts were then baked and their attenuated total reflectance (ATR) FTIR spectra were measured using liquid membrane method. The number of chemical components of the additives was determined by median absolute deviation (MAD), and the spectral information of the pure component was extracted by kernel independent component analysis (KICA).

[Randomized controlled clinical trials of red-hot filiform needle puncturing for knee ostarthritis and inflammatory cytokines in knee articular fluid in senile knee ostarthritis patients].

Objective: To observe the effect of red-hot filiform needle puncturing on the pain severity of knee ostarthritis (OA) and the inflammatory cytokine levels in the knee articular cavity (KAC) fluid in senile knee OA patients so as to find a better therapy for knee OA.

Methods: A total of 200 senile knee OA outpatients (who signed an informed consent) were randomized into treatment group and control group (n = 100/group) according to a random number table and their visiting sequence. Futu (LI 18), Neixiyan (EX-LE 4), Yanglingquan (GB 34), Yinlingquan (SP 9), Zusanli (ST 36), etc.

Microfluidic enrichment of small proteins from complex biological mixture on nanoporous silica chip.

The growing field of miniaturized diagnostics is hindered by a lack of pre-analysis treatments that are capable of processing small sample volumes for the detection of low concentration analytes in a high-throughput manner. This letter presents a novel, highly efficient method for the extraction of low-molecular weight (LMW) proteins from biological fluids, represented by a mixture of standard proteins, using integrated microfluidic systems. We bound a polydimethylsiloxane layer patterned with a microfluidic channel onto a well-defined nanoporous silica substrate.

Aceno[2,1,3]thiadiazoles for field-effect transistors: synthesis and crystal packing.

An efficient synthetic approach to a series of aceno[2,1,3]thiadiazole derivatives is described. 2-TIPS and 2-TES molecules exhibited different crystal packings, and 2-TIPS show good device performances with hole mobility up to 0.4 cm(2) V(-1) s(-1) and an average mobility of 0.

Nanotexture Optimization by Oxygen Plasma of Mesoporous Silica Thin Film for Enrichment of Low Molecular Weight Peptides Captured from Human Serum.

This study investigated the optimization of mesoporous silica thin films by nanotexturing using oxygen plasma versus thermal oxidation. Calcination in oxygen plasma provides superior control over pore formation with regard to the pore surface and higher fidelity to the structure of the polymer template. The resulting porous film offers an ideal substrate for the selective partitioning of peptides from complex mixtures.

Surface engineering on mesoporous silica chips for enriching low molecular weight phosphorylated proteins.

Phosphorylated peptides and proteins play an important role in normal cellular activities, e.g., gene expression, mitosis, differentiation, proliferation, and apoptosis, as well as tumor initiation, progression and metastasis.

Serologic survey of pandemic influenza A (H1N1 2009) in Beijing, China.

Objective: To examine the frequency and distribution of antibodies against pandemic influenza A (H1N1 2009) [H1N1] in populations in Beijing and elucidate influencing factors.

Methods: In January 2010, a randomized serologic survey of pandemic influenza A (H1N1 2009) was carried out. Six districts that were randomly selected with a total of 4601 participants involved in the survey have their antibody level tested by hemagglutination inhibition assay.

Synthesis and thermolytic behavior of tin(IV) formates: in search of recyclable metal-hydride systems.

The synthesis and characterization of the series of organotin formates together with their thermolytic behavior are described. The diformate Bu(n)(2)Sn{OC(O)H}(2) (1) was synthesized by the reaction of Bu(n)(2)SnH(2) with formic acid. The triorganotin monoformate compounds R(3)SnOC(O)H (R = Cy (cyclohexyl)) 3, Mes, (mesityl, 2,4,6-trimethylphenyl) 4, and Dmp (2,6-dimethylphenyl 5) were obtained by the reaction of R(3)SnOH with formic acid.

Combinatorial selection of DNA thioaptamers targeted to the HA binding domain of human CD44.

CD44, the primary receptor for hyaluronic acid, plays an important role in tumor growth and metastasis. CD44-hyaluronic acid interactions can be exploited for targeted delivery of anticancer agents specifically to cancer cells. Although various splicing variants of CD44 are expressed on the plasma membrane of cancer cells, the hyaluronic acid binding domain (HABD) is highly conserved among the CD44 splicing variants.

A ditetrylyne as a π-electron donor: synthesis and characterization of [AgAr'GeGeAr'](+)SbF6(-) and [Ag2Ar'GeGe(F)Ar'](+)SbF6(-) (Ar' = C6H3-2,6(C6H3-2,6-Pr(i)2)2).

The reaction of a digermyne Ar'GeGeAr' (Ar' = C(6)H(3)-2,6-(C(6)H(3)-2,6-Pr(i)(2))(2)) with AgSbF(6) at -40 °C forms the complex (AgAr'GeGeAr')(+)SbF(6)(-), which provides the first example of a heavier group 14 element alkyne analogue behaving as a π donor to a transition metal. The cation (AgAr'GeGeAr')(+) is best described as a hybrid of a π-complex and a σ-metallacyclopropene structure.

[Study on adsorption behavior of crosslinked polyarylonitrile for copper, lead, cadmium and zinc ions by atomic absorption spectrometry].

The crosslinked polymer polyacrylonitrile was synthesized by suspension polymerization using acrylonitrile and divinylbenzene. It has been used as adsorbent of some toxic heavy metals in environmental waters. Its adsorption for metals and the factors which affect the adsorption capacity were studied by atomic absorption spectrometry (AAS).

Improving the quality of acute pain services: experiences of treatment of 5212 patients.

Background: In a retrospective, non-randomized, observational study, we compared methods of postoperative analgesia in 5212 cases treated in 2003 and 2004.

Methods: Patients were allocated to two groups: Group A included 2,796 patients treated in 2004; Group B included 2,419 treated in 2003.The acute pain team was staffed by anaesthesiologists who performed daily visits to patients receiving the APS.

Reversible complexation of isocyanides by the distannyne Ar'SnSnAr' (Ar' = C(6)H(3)-2,6(C(6)H(3)-2,6-(i)Pr(2))(2)).

The reaction of the distannyne Ar'SnSnAr' (Ar' = C(6)H(3)-2,6(C(6)H(3)-2,6-(i)Pr(2))(2)) with tert-butyl or mesityl isocyanide afforded the bis-adducts Ar'SnSnAr'(CNBu(t))(2) or Ar'SnSnAr' (CNMes)(2) in which the isonitriles are reversibly bound under ambient conditions.

Reaction of hydrogen or ammonia with unsaturated germanium or tin molecules under ambient conditions: oxidative addition versus arene elimination.

The reactions of hydrogen or ammonia with germylenes and stannylenes were investigated experimentally and theoretically. Treatment of the germylene GeAr(#)(2) (Ar(#) = C(6)H(3)-2,6-(C(6)H(2)-2,4,6-Me(3))(2)) with H(2) or NH(3) afforded the tetravalent products Ar(#)(2)GeH(2) (1) or Ar(#)(2)Ge(H)NH(2) (2) in high yield. The reaction of the more crowded GeAr'(2) (Ar' = C(6)H(3)-2,6-(C(6)H(3)-2,6-(i)Pr(2))(2)) with NH(3) also afforded a tetravalent amide Ar'(2)Ge(H)NH(2) (3), whereas with H(2) the tetravalent hydride Ar'GeH(3) (4) was obtained with Ar'H elimination.