Individualised Lifestyle Intervention in Polycystic Ovarian Syndrome Women Who Desire Fertility: A Feasibility Study.

Background: Polycystic ovarian syndrome (PCOS) is one of the common causes of anovulatory infertility among women in the reproductive age group. Women with PCOS and obesity often have difficulty in conceiving, and they are more prone for developing metabolic syndrome. Lifestyle modification plays a key role in women with PCOS, who are overweight or obese and is recommended as a first line management option.

Degenerative Temporomandibular Disorders: An Assessment of Bone Trabecular Structure Using Fractal Analysis in Digital Panoramic Radiographs.

Introduction Fractal analysis has proved to be a salient tool to quantitatively assess the qualitative changes in the bone trabeculae of patients with hyperparathyroidism, osteoporosis, and various temporomandibular disorders, including osteoarthritis (OA) and rheumatoid arthritis of temporomandibular joint (TMJ), in several previous studies. The purpose of this study was to use fractal analysis to assess alterations in the trabecular pattern of the mandibular condyle in patients with degenerative temporomandibular disorders. Materials and methods This study comprised 98 subjects with 49 subjects in the study group and 49 subjects in the control group, aged 18-50 years.

Awareness and Perception of Dental Undergraduates in Belagavi District Towards the Newly Proposed National Exit Test for India.

Background:  The National Dental Commission Bill of 2023 introduced the National Exit Test (NExT) as a common final examination for all dental graduates in India, granting them the license to practice. This study evaluated dental undergraduates' awareness and perceptions of the newly proposed NExT.

Methods:  A self-administered questionnaire in English comprising 23 close-ended questions was used to assess the awareness and perception of the students.

Molecular dynamics investigation, Hirshfeld surface analysis, and molecular docking studies by quantum chemical evaluation of new novel NLO 5-hydroxy-3,6,7,8-tetramethoxyflavone.

Context: The molecular structure of the compound, spectroscopic investigations (FT-IR, FT-Raman, and NMR), and the frontier energy level analysis of 5-hydroxy-3,6,7,8-tetramethoxyflavone (5HTMF) were all examined using density functional theory (DFT) methods. Comparisons were made between predicted DFT theoretical vibrational wavenumbers and observed data. The chemical reactivity of 5HTMF was studied using DFT/PBEPBE approach that included frontier orbital energies, optical characteristics, and chemical descriptors.

Effect of Long-Term Embryo Cryopreservation on Subsequent Frozen Embryo Transfer Outcomes: A Retrospective Cohort Study.

Background: The duration of cryopreservation of embryos and its effect on the subsequent pregnancy outcomes, when they have been frozen for a longer duration remains a matter of concern. There is a continuous debate among studies comparing different durations of embryo cryopreservation as the results are contradictory.

Aims: This study aims to find out if long-term cryopreservation of embryos has any effect on pregnancy and perinatal outcomes.

Luminescence studies of a Li Ca SiO :xSm phosphor for the generation of white light under NUV-excited phosphor converting LEDs.

In this paper, we present new aspects of Sm -doped pure Li CaSiO as a suitable candidate for white light emitting diode (WLED) applications. The samples were mainly prepared using a conventional modified solid-state synthesis technique. The structural studies were done using X-ray diffraction and Rietveld refinement.

The impact of simulation education on self-efficacy towards teaching for nurse educators.

Aim: The objective of this study was to assess the impact of a simulation workshop on self-efficacy towards teaching for nurse educators in India. Additionally, we sought to revise and validate a tool to measure self-efficacy in teaching for use with a global audience.

Background: Simulation is an evidence-based teaching and learning method and is increasingly used in nursing education globally.

Medical Professionals and Smartphone Applications.

Ever since the advent of Smartphones, Smartphone applications (SAs) are revolutionizing the contemporary medicine. Smartphone application which was created in view of swift communications among the general public has now intruded the medical fraternity. But the ethics for using these applications to transfer patients' medical records through SA is bewildering among the medical professionals (MPs).

A Recombinant Human Anti-Platelet scFv Antibody Produced in Pichia pastoris for Atheroma Targeting.

Cells of the innate and adaptive immune system are key factors in the progression of atherosclerotic plaque, leading to plaque instability and rupture, potentially resulting in acute atherothrombotic events such as coronary artery disease, cerebrovascular disease and peripheral arterial disease. Here, we describe the cloning, expression, purification, and immunoreactivity assessment of a recombinant single-chain variable fragment (scFv) derived from a human anti-αIIbβ3 antibody (HuAb) selected to target atheromatous lesions for the presence of platelets. Indeed, platelets within atheroma plaques have been shown to play a role in inflammation, in platelet-leucocyte aggregates and in thrombi formation and might thus be considered relevant biomarkers of atherosclerotic progression.

Three-dimensional transesophageal echocardiography-guided transcathetar closure of ruptured noncoronary sinus of valsalva aneurysm.

Sinus of Valsalva aneurysm accounts for only 1% of congenital cardiac anomalies. Sinus of Valsalva aneurysm can cause aortic insufficiency, coronary artery flow compromise, cardiac arrhythmia, or aneurysm rupture. Three-dimensional transesophageal echocardiography (3DTEE) represents an adjunctive tool to demonstrate the ruptured sinus of Valsalva with better delineation.

Comparative evaluation of two different loading doses of dexmedetomidine with midazolam-fentanyl for sedation in vitreoretinal surgery under peribulbar anaesthesia.

Background And Aims: Midazolam-fentanyl (MDZ:FEN) combination has been routinely used for intravenous sedation in ophthalmic surgeries. Dexmedetomidine (DEX), a recent α2 adrenoreceptor agonist indicated for sedation for ophthalmic use at a loading dose of 0.5 μg/kg over 10 min, can cause deeper plane of sedation and surgeon dissatisfaction.

Nymphaea nouchali Burm. f. hydroalcoholic seed extract increases glucose consumption in 3T3-L1 adipocytes through activation of peroxisome proliferator-activated receptor gamma and insulin sensitization.

Nymphaea nouchali Burm. f. (Family - Nymphaeaceae) is a well-known medicinal plant used in the Indian ayurvedic system of medicine for treating diabetes.

Discovery and mapping of genomic regions governing economically important traits of Basmati rice.

Background: Basmati rice, originated in the foothills of Himalayas, commands a premium price in the domestic and international markets on account of its unique quality traits. The complex genetic nature of unique traits of Basmati as well as tedious screening methodologies involved in quality testing have been serious constraints to breeding quality Basmati. In the present study, we made an attempt to identify the genomic regions governing unique traits of Basmati rice.

Crystal structure of (2-formyl-phenolato-κ(2) O,O')oxido(2-{[(2-oxidoeth-yl)imino]-meth-yl}phenolato-κ(3) O,N,O')vanadium(V).

In the unsymmetrical title vanadyl complex, [V(C9H9NO2)(C7H5O2)O], one of the ligands (2-formyl-phenol) is disordered over two sets of sites, with an occupancy ratio of 0.55 (2):0.45 (2).

Crystal structure of aquadioxido(2-{[(2-oxido-ethyl)-imino]-meth-yl}phenol-ato-κ(3) O,N,O')molybdenum(VI).

The mononuclear title complex, [Mo(C9H9NO2)O2(H2O)], contains an Mo(VI) atom in a distorted octa-hedral coordination sphere defined by an Mo=O and an Mo-(OH2) bond to the axial ligands and two Mo-O bonds to phenolate and alcoholate O atoms, another Mo=O bond and one Mo-N bond to the imino N atom in the equatorial plane. The five-membered metalla-ring shows an envelope conformation. In the crystal, individual mol-ecules are connected into a layered arrangement parallel to (100) by means of O-H⋯O hydrogen bonds involving the water mol-ecule as a donor group and the O atoms of neighbouring complexes as acceptor atoms.

Analysis of time-dependent changes in Bitemarks on Styrofoam sheets.

Context: The scope of Bitemarks in forensic dentistry is widening as they help the forensic expert in identifying the perpetuator in medicolegal cases. The greatest challenge in Bitemarks analysis is the time-dependent changes produced in Bitemark patterns on various substrates at the scene of the crime.

Aims: To analyze the time-dependent changes in Bitemarks on Styrofoam sheets.

Conformational stability, vibrational spectra, NLO properties, NBO and thermodynamic analysis of 2-amino-5-bromo-6-methyl-4-pyrimidinol for dye sensitized solar cells by DFT methods.

The Fourier transform infrared (FT-IR) and Fourier transform Raman (FT-Raman) spectra of 2-amino-5-bromo-6-methyl-4-pyrimidinol (ABrMP) were recorded in the region 4000-400 and 3500-100 cm(-1), respectively. The conformational stability, geometrical structure, vibrational frequencies, infrared intensities and Raman activities were carried out by DFT (B3LYP and LSDA) methods with 6-311++G(d,p) basis set. The calculated results show good agreement with observed spectra.

Spectroscopic (FT-IR, FT-Raman and UV-Visible) investigations, NMR chemical shielding anisotropy (CSA) parameters of 2,6-Diamino-4-chloropyrimidine for dye sensitized solar cells using density functional theory.

The molecular structure, geometry optimization, vibrational frequencies of organic dye sensitizer 2,6-Diamino-4-chloropyrimidine (DACP) were studied based on Hartree-Fock (HF) and density functional theory (DFT) using B3LYP methods with 6-311++G(d,p) basis set. Ultraviolet-Visible (UV-Vis) spectrum was investigated by time dependent DFT (TD-DFT). Features of the electronic absorption spectrum in the UV-Visible regions were assigned based on TD-DFT calculation.

In vitro antimicrobial activity and HPTLC analysis of hydroalcoholic seed extract of Nymphaea nouchali Burm. f.

Background: In the Indian ayurvedic system of medicine, Nymphaea nouchali is used for the treatment of diabetes, cutaneous diseases, inflammation, liver disorders, urinary disorders, menorrhagia, blenorrhagia, menstruation problem, as an aphrodisiac, and as a bitter tonic. However, despite its traditional usage as an antimicrobial agent, there is no information regarding its effectiveness in infections caused by pathogenic microbes. Hence, we evaluated 70% ethanol extract of the seeds of N.

Wheat-based traditional flat breads of India.

Wheat forms the basic ingredient for various bakery and traditional products. Wheat-based flat breads are one of the traditional products prepared in different parts of the world. Different regions of the world have inherited different preparation methods since time immemorial, which has led to the existence of traditional flat breads'.