Publications by authors named "On Behalf Of Crown Investigators"
Evolution toward brain death (BD) in out-of-hospital cardiac arrest patients with targeted temperature management (TTM) provides opportunities for organ donation. However, knowledge regarding BD in these patients is limited. We retrospectively analyzed the TTM registry of one hospital where life-sustaining therapy was not withdrawn.
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- Early assessment of neurological outcomes in cardiac arrest survivors is difficult, but using biomarkers like microRNAs (miRNAs) may provide a more objective and accessible method for evaluation.
- In a study, researchers identified specific miRNAs that correlate with survival outcomes following targeted temperature management (TTM) in cardiac arrest patients.
- The study found that measuring early levels of these miRNAs, along with protein biomarkers, significantly improved prediction accuracy for neurological recovery compared to using just protein markers alone.