The effect of honey in oral care intervention against chemotherapy-induced mucositis in pediatric cancer patients: a pilot study.

Objective: Mucositis is one of the common side effects of chemotherapy. This study aimed to identify the effects of honey on oral care interventions to reduce mucositis scores among children undergoing chemotherapy.

Methods: This pilot study was quasi-experimental with pre-post intervention with the control group.

Gastrointestinal helminths of captive proboscis monkey (Nasalis larvatus) in Surabaya zoo, Indonesia.

Background: One of the constrain in proboscis monkey (Nasalis larvatus) conservation is gastrointestinal helminth (GH) infection. Here, we conducted a study to determine the prevalence of GHs in captive proboscis monkeys in Surabaya Zoo, Indonesia.

Methods: Twenty fecal samples were collected from three groups (i.

Health-related quality of life and its relationship with time use, role participation and perceived social support among retirees in Klang Valley and Malacca.

Introduction: With increased life expectancy among older adults in Malaysia, there is an increasing number of years of living after retirement. The role and lifestyle changes can significantly affect time use and participation in everyday life, influencing individuals' quality of life (QoL) and wellbeing. However, limited research has examined the healthrelated QoL and its relationship with time use, role participation and perceived social support among retirees in Malaysia.

Reasons behind providing care for older persons.

Introduction: There is a global increase in the ageing population, and Malaysia is expected to become an ageing country. As elderly individuals experience deterioration in physical and cognitive functions, they often require longterm care from caregivers. This study aims to investigate the reasons why caregivers provide care for older adults at home.

The ethanol extract of cocoa pod husk minimizes hyperalgesia and blood glucose levels in diabetic neuropathy model through transient receptor protein vanilloid (TRPV)-1.

Oxidative stress accumulation becomes a pathophysiological factor in diabetic neuropathy (DN), activating TRPV-1. Resveratrol in cocoa pod husk exhibits antioxidant activity that could be beneficial in DN. This study examined how the ethanol extract of cocoa pod husk (EECPH) affects DN in mice by targeting TRPV-1.

Sequence analysis of the Spike, RNA-dependent RNA polymerase, and protease genes reveals a distinct evolutionary pattern of SARS-CoV-2 variants circulating in Yogyakarta and Central Java provinces, Indonesia.

During the Covid-19 pandemic, the resurgence of SARS-CoV-2 was due to the development of novel variants of concern (VOC). Thus, genomic surveillance is essential to monitor continuing evolution of SARS-CoV-2 and to track the emergence of novel variants. In this study, we performed phylogenetic, mutation, and selection pressure analyses of the Spike, nsp12, nsp3, and nsp5 genes of SARS-CoV-2 isolates circulating in Yogyakarta and Central Java provinces, Indonesia from May 2021 to February 2022.

A Systematic Review of Experimental Studies on the Impact of Empowerment-Based Interventions on Child and Parent Outcomes in the Pediatric Oncology Setting.

Background: Cancer has an impact not only on children but also on parents. Parents play the most crucial role in cancer's symptom control and management. However, as the primary caretakers, parents are frequently unprepared or engage in inappropriate behavior when caring for their children.

The Meaning of Occupation for Adults With Advanced Cancer: A Scoping Review.

Importance: In this scoping review, we explore the meaning of occupation for people with advanced cancer to develop and improve occupation-based services in oncology.

Objective: To identify the meaning(s) of occupation for adults with advanced cancer through relevant peer-reviewed literature.

Data Sources: Scopus, CINAHL, Medline, and PubMed were used to identify peer-reviewed articles published between 2011 and 2021.

The diversity and quality of forages and their potency as herbal anthelmintic for swamp buffalo in Brebes District, Central Java.

Background And Aim: Swamp buffaloes play an important role in the rural economy of Indonesia. They consume various forages during their grazing time, including those with anti-parasitic potential. However, the information about the type and quality of forages and their potential as a natural anthelmintic for swamp buffalo is very limited.

Uncertainty of parents due to having children with cancer: A concept analysis.

Background: Parents of newly diagnosed cancer children often experience significant concerns about the implications of the diagnosis. They find themselves in challenging decision-making situations, navigating through uncertain conditions following the disclosure. Uncertainty is a prevailing issue in healthcare, yet its interpretation and application within the context of health and nursing practice exhibit multiple meanings and variations.

Radiosynthesis, Stability, Lipophilicity, and Cellular Uptake Evaluations of [I]Iodine-α-Mangostin for Breast Cancer Diagnosis and Therapy.

The high rate of incidence and mortality caused by breast cancer encourage urgent research to immediately develop new diagnostic and therapeutic agents for breast cancer. Alpha mangostin (AM) is a natural compound reported to have anti-breast cancer properties. Its electron-donating groups structure allows it to be labeled with an iodine-131 radioisotope to develop a candidate of a diagnostic and therapeutic agent for breast cancer.

General toxicity studies of alpha mangostin from : A systematic review.

Alpha mangostin (AM), the main xanthone derivative contained in mangosteen pericarp (/GM), has many pharmacological activities such as antioxidant, antiproliferation, antiinflammatory, and anticancer. Several general toxicity studies of AM have been previously reported to assess the safety profile of AM. Toxicity studies were carried out by various methods such as on test animals, interventions, and various routes of administration, but the test results have not been well documented.

Stakeholders' perceptions of family planning programs during the COVID-19 period: A descriptive qualitative study.

Aim: The number of unintended pregnancies and the decreasing use of contraceptives during the COVID-19 pandemic are of particular concern to the national population and family planning program. The successful implementation of the family planning program cannot be carried out by the government alone. Still, it requires strong synergy with stakeholders.

Determinant Factors of Post-Partum Contraception among Women during COVID-19 in West Java Province, Indonesia.

Background: One of the manifestations of family development is pregnancy planning, where this method is applied 0-42 days after childbirth. Post-partum contraception is an effort to avoid pregnancy by using contraceptive medicine from 42 days to 84 days after childbirth.

Purpose: This research aims to analyze the attitudes of fertile couples who use contraceptive devices after childbirth during the COVID-19 pandemic and the factors that influence it.

Future Prospective of Radiopharmaceuticals from Natural Compounds Using Iodine Radioisotopes as Theranostic Agents.

Natural compounds provide precursors with various pharmacological activities and play an important role in discovering new chemical entities, including radiopharmaceuticals. In the development of new radiopharmaceuticals, iodine radioisotopes are widely used and interact with complex compounds including natural products. However, the development of radiopharmaceuticals from natural compounds with iodine radioisotopes has not been widely explored.

Increasing midwifery capability on maternal health service.

Objective: This study aimed to determine the differences in midwives' knowledge, attitudes, motivation and abilities regarding maternal health care after an intervention.

Methods: This was an experimental research study with a quasi-experimental pretest-posttest design with a control group. The sample of this study was 66 midwives in Jeneponto Regency; 33 midwives comprised the control group, and 33 comprised the treatment groups.

COVID-19 and ASEAN responses: Comparative policy analysis.

Scholars and policy-makers agree that cross-border and multi-sector cooperation are essential components of coordinated efforts to contain the spread of COVID-19 infections. This paper examines the responses of ASEAN (Association of Southeast Asian Nation) member countries to the COVID-19 pandemic, including the limits of regional cooperation. ASEAN has pre-existing cooperative frameworks in place, including regional health security measures, which, at least theoretically, could assist the region's efforts to formulate cooperative responses to containing a global pandemic.

Massage therapy as a non-pharmacological analgesia for procedural pain in neonates: A scoping review.

Introduction: Neonates who undergo painful medical procedures should be given analgesics to reduce future adverse risks. The evidence for massage therapy (MT) as an analgesic method still varies, both in its terminology and implementation. Only a few studies on this topic have been conducted using a standardised trial approach.

A cross-sectional study on the practice of wet nursing among Muslim mothers.

Background: Breastfeeding and wet nursing have been synonymous since ancient times. The practice of wet nursing of another woman's child in Malaysia is on the rise due to the emergence of awareness among the public about the importance and advantages of breast milk. However, problems arise when there is no systematic system to record and trace the milk mother and milk child data, especially for Muslim participants as milk kinship could affect their relationship status in Islam.

The purity identification and radiolabeling of α-mangostin with technetium-99m.

Alpha-mangostin (AM) is a natural compound that has the greatest activity in breast cancer. Radiolabeling AM with technetium-99 m (Tc-99m) has a function as breast cancer radiotracer. This study is aimed to identify the purity of Tc-99m-labeled AM.

Advanced drug-delivery systems: mechanoresponsive nanoplatforms applicable in atherosclerosis management.

Nanoplatforms have been used extensively as advanced carriers to enhance the effectiveness of drug delivery, mostly through passive aggregation provided by the enhanced permeability and retention effect. Mechanical stimuli provide a robust strategy to bolster drug delivery performance by increasing the accumulation of nanoplatforms at the lesion sites, facilitating on-demand cargo release and providing theranostic aims. In this review, we focus on recent advances of mechanoresponsive nanoplatforms that can accomplish targeted drug delivery, and subsequent drug release, under specific stimuli, either endogenous (shear stress) or exogenous (magnetic field and ultrasound), to synergistically combat atherosclerosis at the molecular level.