CDK regulators-Cell cycle progression or apoptosis-Scenarios in normal cells and cancerous cells.

Serine/threonine kinases called cyclin-dependent kinases (CDKs) interact with cyclins and CDK inhibitors (CKIs) to control the catalytic activity. CDKs are essential controllers of RNA transcription and cell cycle advancement. The ubiquitous overactivity of the cell cycle CDKs is caused by a number of genetic and epigenetic processes in human cancer, and their suppression can result in both cell cycle arrest and apoptosis.

Serum immunoglobulin levels in Chinese male schizophrenics.

Serum immunoglobulin levels (IgA, IgG and IgM) were determined by an immunoelectrophoretic method in two separate series of Chinese male schizophrenics and healthy controls. In the first series, 41 healthy male blood donors and 98 schizophrenic patients in different stages of the disease were investigated. In the second series a random sample of 50 acutely ill male schizophrenic patients were investigated along with a second group of healthy male subjects.