Prediction of knee osteoarthritis progression using radiological descriptors obtained from bone texture analysis and Siamese neural networks: data from OAI and MOST cohorts.

Background: Trabecular bone texture (TBT) analysis has been identified as an imaging biomarker that provides information on trabecular bone changes due to knee osteoarthritis (KOA). In parallel with the improvement in medical imaging technologies, machine learning methods have received growing interest in the scientific osteoarthritis community to potentially provide clinicians with prognostic data from conventional knee X-ray datasets, in particular from the Osteoarthritis Initiative (OAI) and the Multicenter Osteoarthritis Study (MOST) cohorts.

Patients And Methods: This study included 1888 patients from OAI and 683 patients from MOST cohorts.

Trabecular bone texture analysis of conventional radiographs in the assessment of knee osteoarthritis: review and viewpoint.

Background: Trabecular bone texture analysis (TBTA) has been identified as an imaging biomarker that provides information on trabecular bone changes due to knee osteoarthritis (KOA). Consequently, it is important to conduct a comprehensive review that would permit a better understanding of this unfamiliar image analysis technique in the area of KOA research. We examined how TBTA, conducted on knee radiographs, is associated to (i) KOA incidence and progression, (ii) total knee arthroplasty, and (iii) KOA treatment responses.

Multi-Grid Phase Field Skin Tumor Segmentation in 3D Ultrasound Images.

The aim of this paper is to present a new method for skin tumor segmentation in the 3D ultrasound images. We consider a variational formulation, the energy of which combines a diffuse interface phase field model (regularization term) and a log-likelihood computed using nonparametric estimates (data attachment term). We propose a multi-grid implementation with the exact solutions which has the advantage to avoid space discretization and numerical instabilities.