Oral Microbiome Dynamics in Treated Childhood Caries: A Comparative Study.

Background: Dental caries is a multifactorial disease that results from interactions of susceptible host, cariogenic microorganisms, and fermentable carbohydrate sources. Our study explored oral microbiome shifts in children before and after dental treatment.

Methods: Initial saliva samples were collected from caries free, moderate caries, and severe caries children based on the decayed, missing, and filled teeth index (DMFT/dmft) index.

Acute oral toxicity evaluation of synbiotic mixture containing Streptococcus salivarius K12 and Musa acuminata aqueous peel extract in Sprague-Dawley rats.

Background: The combination of S. salivarius K12 and M. acuminata are being used as synbiotic, but its safety evaulation is required.

Gait alteration during turning while walking in older adults with benign paroxysmal positioning vertigo.

Background: Older adults with Benign Paroxysmal Positioning Vertigo (BPPV) may present with unsteadiness that affects gait patterns.

Objective: This study investigated the spatiotemporal gait parameters and indicators of turning difficulty during the Timed Up and Go (TUG) test in older adults with BPPV.

Methods: This case-controlled study collected data from older adults aged 65 and above with BPPV, young adults with BPPV and older adults without BPPV.

Intraperitoneal Injection of the Outer Membrane Vesicle (OMV) Stimulated Expressions of Neuroinflammatory Markers and Histopathological Changes in the Brains of Adult Zebrafish.

is the major pathogenic bacteria found in the subgingival plaque of patients with periodontitis, which leads to neuroinflammation. The bacteria destroy periodontal tissue through virulence factors, which are retained in the bacteria's outer membrane vesicles (OMV). This study aimed to determine the real-time effect of an intraperitoneal injection of OMV on the production and expression of inflammatory markers and histopathological changes in adult zebrafishes' central nervous systems (CNS).

How new pharmacists handled COVID-19 misinformation: A qualitative study.

Background: New pharmacists, PharmD graduates of 2020 and 2021, faced the unique challenge of entering the workforce during the volatile and divisive COVID-19 pandemic. They had to navigate patient-driven misinformation while adapting to evolving roles, including the distribution and administration of COVID-19 vaccines. Understanding the experiences of new pharmacists during this period is crucial for professional development and patient care.

Molecular prevalence of , and and their associations with Mafriwal cattle's age groups.

Objective: This study was designed to determine the molecular prevalence of hemoparasites and their associations with Mafriwal cattle's age groups.

Materials And Methods: Blood samples were taken from the coccygeal veins of calves ( 92), yearlings ( 95), lactating ( 90), and dry ( 94) cows, which were subjected to microscopic and molecular identification of hemoparasites. The prevalence rate was determined based on the proportion of infected samples in the observed samples.

Reliability, interrelationships, and minimal detectable changes of strength and power metrics among well-trained rugby sevens players.

Despite the importance of strength and power in rugby skills and match outcomes, there exists a noticeable gap in the measurement consistency and estimation of a true change of typical assessments designed to assess these qualities. To address this gap, we investigated the between-session reliability, interrelationships, and minimal detectable changes (MDC) of commonly used strength and power measures in team sports. Sixteen national-level rugby 7 s players were tested on two occasions, one week apart.

Exploring Fungal Candidates from Aromatic Rhizosphere as Biological Controls Against Three Haplotypes.

<b>Background and Objective:</b> Blast disease (<i>Pyricularia oryzae</i>) is a major disease-causing yield losses in rice crops worldwide. Disease control using resistant varieties is less effective due to the high genetic variation in <i>P. oryzae</i> populations in the field and the use of synthetic fungicides hurts the diversity of biological agents.

Willingness to use PrEP among PrEP naïve men who have sex with men: a meta-analysis.

This study aimed to measure the pooled estimate of willingness to use HIV pre-exposure prophylaxis (PrEP) (WTUP) among PrEP-naïve United States (U.S.)-based men who have sex with men (MSM).

Uncovering the presence of CVPD disease in citrus varieties of South Sulawesi, Indonesia: A molecular approach.

Background: The citrus vein phloem degeneration (CVPD) disease is one of important diseases that infects citrus plants and threatens global citrus production and quality due to its severe symptoms and rapid spread. In the 2000s, South Sulawesi Province as one of the citrus producers in Indonesia reported CVPD infection. To date, it is still uncertain as to whether the citrus production center has already been rid of the CVPD infection, keeping in mind the low prevalence of certified citrus saplings use and sub-optimal management of plantations by farmers.

Culture Optimization of Pomelo Seeds ( (Burm.) Merr.): A South Sulawesi Orange.

<b>Background and Objective:</b> Indonesia boasts a variety of delicious tropical fruits, including pomelo, mainly grown in Pangkep Regency, South Sulawesi Province. However, in this region, some challenges hinder such as inadequate care, aging trees and limited seed supply hinder productivity in this region. <i>In vitro</i> culture methods present a solution by rapidly producing high quality, disease-free pomelo seeds.

Diverse Morphology and Anatomy of <i>Citrus</i> Spp. (Orange) in South Sulawesi, Indonesia Plantations: A Comprehensive Study.

&lt;b&gt;Background and Objective:&lt;/b&gt; South Sulawesi, one of the Indonesian provinces, is a producer of oranges with various varieties grown extensively for export and domestic use. Information about the diversity of oranges is crucial for plant breeding and germplasm conservation. This study aims to analyze the diversity of oranges from several plantation centers in South Sulawesi based on morphological and anatomical characteristics.

The Development of a New Tool to Help Patients and Their Providers Evaluate Self-Management of Type 2 Diabetes Mellitus.

Diabetes self-management or self-care activity related to diet, physical activity, and glucose monitoring, among other things, is recognized as important to effectively managing this condition. The aim of this study was to create an assessment tool for evaluating knowledge and self-management behavior in Type 2 Diabetes Mellitus (T2DM) for patients and their providers. The study utilized an online survey with a cross-sectional design of adults diagnosed with Type 2 diabetes.

Student Service-Learning Projects: Good Intentions, Questionable Impact.

Student pharmacist-led service-learning projects aimed at community engagement generally provide health education while promoting the pharmacy profession. Many such projects often assume the needs and wants of community residents, and key community partners are often left off the decision-making table when it comes to planning. This paper will offer some reflection and guidance for student organizations to consider when planning projects, with a focus on local community partnerships to identify and address needs for more meaningful and sustainable impact.

Effective Modalities of Periodontitis Induction in Rat Model.

Induction of periodontal disease using the rat model is the preferred model for human periodontal disease studies that are related to gene expression, mechanisms of inflammatory regulation, microbial and host responses, resolution, and the healing process. There are 3 methods that are frequently used to induce periodontal disease, which are: ligature application, oral bacterial inoculation, and the lipopolysaccharide injection technique. In the ligature model, sterile non-absorbable sutures or orthodontic wires are widely used to induce local irritation and bacterial plaque accumulation.

Embryonic mercury exposure in zebrafish: Alteration of metabolites and gene expression, related to visual and behavioral impairments.

The widespread presence of mercury, a heavy metal found in the environment and used in numerous industries and domestic, raises concerns about its potential impact on human health. Nevertheless, the adverse effects of this environmental toxicant at low concentrations are often underestimated. There are emerging studies showing that accumulation of mercury in the eye may contribute to visual impairment and a comorbidity between autism spectrum disorders (ASD) trait and visual impairment.

Predicting Key Genes and Therapeutic Molecular Modelling to Explain the Association between () and Alzheimer's Disease (AD).

The association between () and Alzheimer's disease (AD) remains unclear. The major aim of this study was to elucidate the role of genes and molecular targets in -associated AD. Two Gene Expression Omnibus (GEO) datasets, GSE5281 for AD (n = 84 Alzheimer's, n = 74 control) and GSE9723 (n = 4 , n = 4 control), were downloaded from the GEO database.

Overview on postmenopausal osteoporosis and periodontitis: The therapeutic potential of phytoestrogens against alveolar bone loss.

Osteoporosis and periodontitis are two major chronic diseases of postmenopausal women. The association between these two diseases are evident through systemic bone loss and alveolar bone loss. Both postmenopausal osteoporosis and periodontitis impose a considerable personal and socioeconomic burden.

Paradoxical reduction of plasma lipids and atherosclerosis in mice with adenine-induced chronic kidney disease and hypercholesterolemia.

Background: Atherosclerotic cardiovascular disease is prevalent among patients with chronic kidney disease (CKD). In this study, we initially aimed to test whether vascular calcification associated with CKD can worsen atherosclerosis. However, a paradoxical finding emerged from attempting to test this hypothesis in a mouse model of adenine-induced CKD.

Evaluation of growth parameters and body condition score on weaning stages of Saanen goats.

Objective: There are three objectives in this study; 1) to measure the live weight of pre-and post-weaning Saanen kids; 2) to determine the growth curves between males and females pre-and post-weaning Saanen kids; and 3) to analyze the body condition score (BCS) between male and female pre-and post-weaning kids.

Materials And Methods: This study included pre-weaning kids aged 1 month, as well as post-weaning kids aged 3-6 months. 10 pre-weaning purebred Saanen kids ( = 5 male and = 5 female) and 20 post-weaning Saanen kids ( = 10 male and = 10 female) were employed in this investigation.

Phytochemical Profiling, Antioxidant, Antimicrobial and Cholinesterase Inhibitory Effects of Essential Oils Isolated from the Leaves of and .

The current studies were focused on the phytochemical profiling of two local wild Artemisia species, Artemisia scoparia and Artemisia absinthium leaves’ essential oils, extracted via the hydro distillation method along with evaluation of their antioxidant as well as antimicrobial effects. The constituents of EOs were identified using a combined gas chromatography-mass spectrometric (GC-MS) technique. A total of 25 compounds in A.

Evaluation methods for vaccination campaigns on college campuses: A scoping review.

Background: Vaccinations are successful, cost-effective tools to prevent the spread of certain infectious diseases. Many colleges conduct vaccination campaigns on their campuses for various vaccine-preventable diseases, including measles, mumps, influenza, HPV, and most recently, for SARS-CoV-2, the virus responsible for COVID-19. Implementing these campaigns requires substantial effort and understanding their effectiveness is an important factor in justifying these programs.