Evaluating the Efficacy of Peroneus Longus Tendon as an Autograft for Anterior Cruciate Ligament Reconstruction in Indian Female Patients: A Prospective Cohort Study.

Background Anterior cruciate ligament (ACL) injuries are prevalent, especially among active individuals, and are increasingly observed even in Indian women who are not active in sports. ACL reconstruction (ACLR) is commonly performed using various graft options, but optimal choices for women remain debated. The aim of our study was to examine the use of the peroneus longus tendon as an autograft for ACLR in Indian female patients.

A Dilemma in the Management of Distal Tibia Fractures Solved by Minimally Invasive Percutaneous Plate Osteosynthesis Technique: A Prospective Study.

Introduction Managing distal tibia fractures is challenging for trauma surgeons because of their peculiar anatomy with less soft tissue coverage and poor blood supply. There are various treatment options for distal tibia fractures such as open reduction and plating, minimally invasive percutaneous plate osteosynthesis, and intramedullary interlocking nailing. Open reduction and internal fixation can lead to excessive soft tissue dissection and devascularization of fracture fragments.

Analyzing Children's Weight Growth Variations and Associated Factors in Ethiopia, India, Peru, and Vietnam: Using Fractional Polynomial Mixed-Effects Model.

Background: Children's growth is increasingly considered a key mediator of later life outcomes. When examining weight growth, the correlation between repeated observations on the same subject must be regarded as well-modelled. This study aimed to analyze children's weight growth variations and associated factors in Ethiopia, India, Peru, and Vietnam using a fractional polynomial mixed-effects model.

Outcome of Open Repair of Thoracoabdominal Aortic Aneurysm in Takayasu Arteritis: A Retrospective Analysis.

Background: Takayasu Arteritis (TA) is an immune mediated arteritis causing inflammation of the aorta and its branches, which can result in aortic aneurysms. Our aim is to describe the outcome of surgical management in these patients who presented with Thoracoabdominal aortic aneurysm (TAAA).

Methods: Between 2003 and 2023, 40 TA patients with TAAA underwent operative repair.

Enhanced Optical Management in Organic Solar Cells by Virtue of Square-Lattice Triple Core-Shell Nanostructures.

This research focuses on enhancing the optical efficacy of organic photovoltaic cells, specifically their optical absorbance and electrical parameters. The absorbance of photons in organic solar cells (OSCs) was studied by incorporating an optical space layer and triple core-shell square-lattice nanostructures. For better chemical and thermal stability, a dielectric-metal-dielectric nanoparticle can be replaced for embedded metallic nanoparticles in the absorption layer.

Novel technique of left atrial appendage occlusion-a pilot study.

A clot in the left atrial appendage (LAA) is an important cause of cardio-embolic stroke. Concomitant occlusion of the LAA during cardiac surgery is found to have reduced postoperative stroke. A study was designed to observe the results of LAA occlusion in 17 patients undergoing coronary artery bypass graft surgery (CABG) and aortic valve replacement (AVR).

Targeting alarmin release reverses Sjogren's syndrome phenotype by revitalizing Ca signalling.

Background: Primary Sjogren's syndrome (pSS) is a systemic autoimmune disease that is embodied by the loss of salivary gland function and immune cell infiltration, but the mechanism(s) are still unknown. The aim of this study was to understand the mechanisms and identify key factors that leads to the development and progression of pSS.

Methods: Immunohistochemistry staining, FACS analysis and cytokine levels were used to detect immune cells infiltration and activation in salivary glands.

Leaf Extract Templated Synthesis of CoO Nanoparticles for Electrochemical Sensor and Antibacterial Applications.

Green synthesis of metal oxide nanoparticles (NPs) is a viable alternative methodology because of cost-effective and availability of environmentally friendly templates for desired application, which has attracted the attention of researchers in recent years. In the present study, CoO NPs were synthesized in various volume ratios in the presence of leaf extract as a template. The synthesized CoO NPs were characterized by X-ray diffraction (XRD), scanning electron microscopy-energy dispersive X-ray spectroscopy (SEM-EDX), transmission electron microscopy (TEM), high resolution transmission electron microscopy (HRTEM), surface area electron diffraction (SAED), UV-Vis diffuse reflectance spectroscopy (UV-DRS), and Fourier transform infrared (FTIR) spectroscopy.

Oral clonidine as a pre-anesthetic medication in hair transplantation surgery-A pilot study.

Background: Hair transplantation (HT) is a safe and rewarding procedure for a patient as well as the surgeon. Clonidine may be a good adjuvant in HT because of its analgesic, anxiolytic, and sedative effects.

Objective: To study efficacy of Clonidine as a preoperative medication in HT.

Short-term effects of a social media-based intervention on the physical and mental health of remotely working young software professionals: A randomised controlled trial.

The present study aimed to explore the short term effects of a social media-based intervention on the physical and mental health of the software professionals working remotely during the pandemic. Sixty software professionals with poor physical and mental health were randomised to Facebook-based intervention (FIIT) and a control (CONT) group for 2 months. Forty-six remote workers (26.

Association between physical and mental health variables among software professionals working at home: a secondary analysis.

The association of physical activity (PA) or sedentary behaviour (SB) with mental health in remotely working software professionals remains unclear. We administered a secondary analysis of physical health variables (PA and SB time during work and non-work days) and mental health variables (stress, anxiety, depression) from a primary study. Ninety-five per cent of the participants ( = 76) did not meet the global PA recommendations.

Geriatric Depression and Cognitive Impairment-An Update.

Background: Depression and cognitive impairment often coexist in older adults. The relation between depression and cognitive impairment is complex. The objective of this article is to review recent literature on cognitive impairment in older adults with depression and provide clinicians an update.

Maternal lineage of Nicobari pig () correlated with migration of , a native tribal population of Andaman and Nicobar Islands, India.

Nicobari pig is reared by , a native tribal population of Andaman and Nicobar Islands. Nicobari pig has maintained its genetic identity due to geographical isolation. This communication is the first report on maternal inheritance of Nicobari pigs.

A Comparative Study on the Health Problems and Substance Abuse among the Tobacco Farmers and Non-Tobacco Farmers in Hassan District, Karnataka.

Background And Aims: India ranks third in the worldwide tobacco production (2017), and it is increasing every year. Hassan is an important tobacco growing district in Karnataka with over 12,000 growers. These growers are exposed to health risks during cultivation of tobacco, pesticide exposure, long duration of work, mental stress, and nicotine toxicity - Green Tobacco Sickness (GTS) due to direct handling of green tobacco leaves.

Impact of Surface Treatment with Different Repair Acrylic Resin on the Flexural Strength of Denture Base Resin: An Study.

Aim And Objective: The aim and objective of the present study was to assess the flexural strength of denture base resin based on surface treatment with different acrylic resin repair materials.

Materials And Methods: Totally, 120 heat-polymerized polymethyl methacrylate denture base resin materials which are rectangular shaped with the size of 65 mm × 10 mm × 2.5 mm were fabricated.

Tri-Model Therapy: Combining Macrocyclic Lactone, Piperazine Derivative and Herbal Preparation in Treating Humpsore in Cattle.

Stephanofilariasis or humpsore is a chronic parasitic dermatitis of cattle. Various treatment regimens were attempted in the past but were found to be partially effective. Here, we claim a successful treatment regime using an FDA-approved macrocyclic lactone, a piperazine derivative, and an herbal preparation.

Host-Parasite Interaction in Infestation in Porcine Model with a Preliminary Note on Its Genetic Lineage from India.

The burrowing mite causes scabies in humans or mange in animals. It infests a wide range of mammalian species including livestock, companion animals, wild animals, and humans. Differential diagnosis of varieties is key for epidemiological studies and for formulation of an eradication program.

Study of neuropsychological deficits in late onset depression.

Background: Older adults with depression often have cognitive deficits contributing to higher morbidity and increased risk for conversion to dementia. Research on this area is limited from India.

Objective: The objective of the current study is to examine the neuropsychological measures in older adults with Late-onset depression (LOD) compared to healthy controls (HC).

Tracing the genetic root of Trinket cattle: an endangered cattle population of a small isolated island of Nicobar group of islands.

Trinket cattle are the inhabitant of a small island called Trinket, which is one of the picturesque islands of Andaman. This herd is thought to be of Danish leftover during their dynasty in Nicobar archipelago. When the island was abandoned by foreign invaders, indigenes utilized the animals for the purpose of meat.

Assessment of Protein Profiles of RNAlater Stored and Fresh PBMC Cells Using Different Protein Extraction Buffers.

For proteome analyses, the tissue samples are mostly preserved either snap frozen or formalin-fixed, paraffin-embedded form. Use of RNAlater-a non-toxic solution primarily used to stabilize the RNA content of samples-in tissue preservation for proteome analysis recently described equally reliable with snap-frozen preservation in human tissues. Even though RNALater storage has great potential in the preservation of Peripheral Blood Mononuclear Cells (PBMC), its impact on the results of proteome analysis is poorly described at qualitative and quantitative measures.

A Natural Quinazoline Derivative from Marine Sponge Induces Apoptosis of Breast Cancer Cells via ROS Production and Intrinsic or Extrinsic Apoptosis Pathways.

Here, we report the therapeutic potential of a natural quinazoline derivative (2-chloro-6-phenyl-8H-quinazolino[4,3-b]quinazolin-8-one) isolated from marine sponge against human breast cancer. The cytotoxicity of the compound was investigated on a human breast carcinoma cell line (MCF-7). Antiproliferative activity of the compound was estimated by 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay.

Evaluation and Identification of Promising Introgression Lines Derived From Wild Species for Broadening the Genetic Base of Cultivated Pigeonpea [ (L.) Millsp.].

Pigeonpea [ (L.) Millsp.], a multipurpose and nutritious grain legume crop, is cultivated for its protein-rich seeds mainly in South Asia and Eastern and Southern Africa.

Late Effects of Breast Cancer Treatment and Outcome after Corrective Interventions.

Purpose: To study the late toxicities of treatment and its impact on Breast cancer survivors among Indian patients. Materials and Methods: Our study recruited 152 curatively treated non metastatic carcinoma breast patients. The baseline demographic details, disease related and treatment related information were collected.