Publications by authors named "Mrinalini"

Irrigation plays a pivotal role in the success of root canal treatments. The development of innovative, less hazardous irrigating solutions is necessary because of the inherent limitations of the gold standard, sodium hypochlorite. Since probiotics have proven to be effective in treating common oral diseases such as periodontitis and dental caries, they have gained attention in the field of endodontics as well.

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  • Advances in endodontics over the last 30 years, particularly through technology, have led to improved precision in complex cases.
  • The dental operating microscope is highlighted as a key innovation, although its adoption in general practice has been slow due to behavioral factors.
  • A case series demonstrates the benefits of using the microscope in varying endodontic scenarios, emphasizing its role in enhancing visibility, improving procedural success, and encouraging regular use in dental practice.
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The era of minimally invasive dentistry has led to the development of new access cavity designs. The impact of various access cavity designs on the fracture resistance of teeth has been extensively studied. The primary aim of this systematic review and meta-analysis is to evaluate and compare the effects of recent modifications in endodontic access cavity design- specifically, conventional, conservative, and truss designs on tooth fracture resistance.

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Introduction: The purpose of this study was to evaluate effect of cryotreated and warm sodium hypochlorite (NaOCl) on postoperative pain in patients with symptomatic irreversible pulpitis and symptomatic apical periodontitis.

Methods: Sixty-six individuals with preoperative pain scores of ≥54 mm on the Heft Parker Visual Analogue Pain Scale (HP-VAS) diagnosed with symptomatic irreversible pulpitis and symptomatic apical periodontitis as per the American Association of Endodontists guidelines in mandibular molars were included. The preparation of the access and the root canals was instrumented and irrigated in accordance with a standard protocol.

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  • The text discusses how structural similarities in organic molecules lead to narcissistic self-sorted phenomena, enhancing exciton dissociation and charge separation in solar cells.
  • It presents two π-conjugated derivatives, one being a zinc-porphyrin linked to benzothiadiazole (PB) as the acceptor and anthracene (PA) as the donor, which form unique 1D nanofibers and aggregates.
  • The study highlights that the electrical properties of these self-sorting assemblies are influenced by the electrostatic potential differences between PA and PB, achieving a conductivity of 0.14 S cm, which aids in the development of more effective photovoltaic materials.
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Background: Root canal re-treatment (RCR) cases are considered some of the most challenging cases in the field of endodontics, as they are mostly associated with various iatrogenic errors such as ledge formation, incomplete biomechanical preparation, file separation, and incomplete obturation. These iatrogenic errors lead to defective niches within root canals that may act as reservoirs for various viable microorganisms. Such residual microbial niches may cause postoperative pain even after thorough debridement and reshaping the canals, ultimately leading to a poor prognosis for the tooth.

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The primary factors that govern the selectivity and efficacy of CO photoreduction are the degree of activation of CO on the active surface sites of photocatalysts and charge separation/transfer kinetics. In this context, the rational synthesis of heterostructured MXene-coupled CeO-based photocatalysts with different loading concentrations of TiCMXene via a one-step hydrothermal approach has been undertaken. These photocatalysts exhibit a shift in X-ray diffraction peaks to higher 2θ values and changes in stretching vibrations of 5 wt % TiCMXene/CeO(5-TC/Ce) that indicate interaction between TiCMXene and CeO.

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The synergistically co-catalyst-decorated -based heterostructured photocatalysts have been synthesized by a hydrothermal approach with varied loading concentrations of to drive the hexavalent chromium reduction efficiently. The formation of the heterostructured photocatalyst was confirmed by the appearance of X-ray diffraction (XRD) peaks corresponding to the monoclinic phase and and also the antisymmetric (834 cm) and symmetric stretching (715 cm) of tetrahedral VO and D (1330 cm) and G (1570 cm) bands corresponding to in the Raman spectrum. The worm-like structures of nanocrystals grew onto the lamellar sheets of , as shown by field emission scanning electron microscopy (FESEM), and has an increased surface area of 15.

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Background: Following the mpox 2022 outbreak, several high-income countries have developed plans with inclusion criteria for vaccination against the mpox disease. This study was carried out to map the factors influencing mpox vaccination uptake to help address the challenges and increase vaccination confidence.

Methods: This was a study based on Tweet analysis.

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Electric field control of magnetodynamics in magnetoelectric (ME) heterostructures has been the subject of recent interest due to its fundamental complexity and promising applications in room temperature devices. The present work focuses on the tuning of magnetodynamic parameters of epitaxially grown ferromagnetic (FM) LaSrMnO(LSMO) on a ferro(piezo)electric (FE) Pb(MgNb)O-PbTiO(PMN-PT) single crystal substrate. The uniaxial magnetic anisotropy of LSMO on PMN-PT confirms the ME coupling at the FM/FE heterointerface.

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Background: The stigma associated with monkeypox (mpox) may prevent people from following recommended guidelines. Using a "model of stigma communication," this study maps and determines the mpox stigma on Twitter among LGBTQ+ (Lesbian, gay, bisexual, transgender, queer and more) community.

Methods: The tweets that contained the terms '#monkeypox', '#MPVS', '#stigma', and '#LGBTQ+' and were published between May 01, 2022 and Sept 07, 2022 were extracted.

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  • - Zebrafish (Danio rerio) is becoming a popular choice for research on neurobehavioural disorders due to its genetic similarity to humans and its effectiveness in overcoming challenges faced by other experimental models.
  • - The review highlights advancements in using zebrafish for neuroactive drug screening, detailing various tests, protocols, and tools used in this research.
  • - It also discusses breeding and maintenance methods of zebrafish and outlines potential future research directions to further explore its role in neuroscience studies.
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Objective: The research for analyzing the smile characteristics in the Indian population has been limited with contradictory outcomes. This consensus statement aims to critically review the literature and provide basic practice guidelines on dental aesthetics related to the Indian population.

Clinical Considerations: 9 clinicians and 6 resource persons from dental colleges in India collaborated in this consensus statement which covered 6 topics along with 6 introductory and 6 conclusive remarks.

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The molecular basis for the evolution of novel phenotypes is a central question in evolutionary biology. In recent years, dung beetles have emerged as models for novel trait evolution as they possess distinct precopulatory traits such as sexually dimorphic horns on their head and thorax. Here, we use functional and evolutionary genomics to investigate the origins and the evolution of postcopulatory reproductive traits in male dung beetles.

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  • * The studies indicate that these BODIPY o-OPhos derivatives exhibit improved optical properties, characterized by increased fluorescence intensity and high quantum yields, valuable for applications in OLEDs and organophosphorus agents.
  • * Electrochemical analysis shows that derivative 5ak has notable redox activity, while computational models indicate significant electronic structure features, positioning the developed derivatives for use in fluorescent probes and bioimaging technologies.
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Identifying the genetic architecture underlying phenotypic variation in natural populations and assessing the consequences of polymorphisms for individual fitness are fundamental goals in evolutionary and molecular ecology. Consistent between-individual differences in behaviour have been documented for a variety of taxa. Dissecting the genetic basis of such behavioural differences is however a challenging endeavour.

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  • There is a significant challenge in studying ant venom due to a lack of databases that can accurately identify venom protein sequences and functions.
  • To address this, researchers created a sequence database using venom gland transcriptomics, which helped match mass spectrometry data to specific venom transcripts.
  • This approach led to identifying four times more proteins than previous methods and uncovered potential new peptides for pharmaceutical development, specifically those with inhibitor cysteine knot motifs.
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  • Researchers studied the venom of the European red ant using transcriptomic and proteomic techniques, identifying 13 new "myrmicitoxins" related to known ant venom peptides, including a modified EGF-like toxin.
  • They tested the insecticidal properties of these toxins on blowflies and found six with significant activity, some of which caused paralysis at certain doses.
  • The most effective peptide, U-MYRTX-Mri1a, showed strong neurotoxic effects initially, but these effects were reversible after 24 hours, and no insecticidal activity was observed at higher doses.
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  • This study focuses on the venom proteins of a newly discovered subspecies of the critically endangered Anatolian meadow viper from Turkey, using advanced techniques in venomics.
  • Researchers applied a mix of venom gland transcriptomics and two methods of proteomics to accurately characterize the venom composition and functionality.
  • They discovered a total of 96 toxin-related transcripts, with snake venom metalloproteinases being the most prevalent, which enhances understanding of venom variability among closely related viper subspecies.
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  • Stimuli-responsive materials are gaining popularity in digital tech, sensors, and biomedical fields due to their ability to quickly react to various external stimuli like light and temperature.
  • The interaction of these stimuli with organic materials improves their physical and chemical properties, enhancing features like thermal stability and biocompatibility.
  • Recent advancements focus on materials involving mixed valence species and non-covalent interactions, which show potential for use in flexible electronics, drug delivery, pollutant detection, and bioimaging, highlighting the need for further research in this area.
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An efficient acid-catalyzed propargylation/aza-annulation sequence was developed under metal-free reaction conditions, thus leading to a one-pot synthesis of a variety of substituted β-carbolines starting from propargylic alcohols and indole 2-carbonyls. This versatile strategy was further extended to the synthesis of 5-azaindoles and 5-azabenzothiazoles. Optical properties suggested that manipulation of electron donor and acceptor moieties on β-carbolines has an impact on their ground and excited state electronic behavior.

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  • * The study focuses on specific ferrocene derivatives linked to porphyrin, which undergo different binding mechanisms when voltage is applied during electrolysis in CHCl, leading to the formation of unique materials.
  • * Analysis reveals that one derivative forms amorphous aggregates while the other forms crystalline nanoflakes, with structural characteristics identified through SEM, TEM, and X-ray diffraction techniques.
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Today's solar cells are exceptionally in demand whilst excess exploitation of natural fossil fuels. In this context, the first and second generation solar cells commercially available in market for more than decades however limitations in production cost and large-scale applications insist to generate inexpensive materials for fabrication. Thereby, organic materials based solar cells explored and emerging as third generation solar cells which possess flexibility, low cost and large-scale applications.

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Venom proteins evolve rapidly, and as a trophic adaptation are excellent models for predator-prey evolutionary studies. The key to a deeper understanding of venom evolution is an integrated approach, combining prey assays with analysis of venom gene expression and venom phenotype. Here, we use such an approach to study venom evolution in the Amazon puffing snake, , a generalist feeder.

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