A dual-mode colorimetric and fluorometric sensor based on water soluble silver nanoclusters (AgNCs@PEI) is developed for quantitative and visual detection of ascorbic acid (Asc A). The detection method relies on the Asc A induced aggregation of AgNCs@PEI, which resulted in fluorecsence quenching of the sensor. The clusters exhibited a unique combination of static and collisional quenching with a wide range of dynamic detection (1-10 µM) Linear relationship was observed in the concentration range 10-10 µM using fluorescence and 0.
View Article and Find Full Text PDFImmunosensors are used to provide simple, quick and effective ways to detect analytes for the diagnosis of a number of diseases. This work reports on a novel optical immunosensor based on thyroxine antibody labeled gold nanoparticles (anti-T4/C-AuNPs) for the sensitive detection of the thyroxine (T4) hormone. T4 hormone is a reliable diagnostic biomarker present in the human blood serum that is necessary for normal neural development and cellular metabolism.
View Article and Find Full Text PDFJ Cutan Aesthet Surg
October 2012
Aim: To study and compare the efficacy of TCA (70%) and phenol (80%) in the treatment of freckles.
Settings And Design: A prospective study was done, over one year, on patients having freckles on the face. The freckles on the right side of the face were treated with TCA (70%) and those on the left side of the face were treated with phenol (80%).