Early Postoperative Outcome of Continuous Heparin Infusion versus Intermittent Intravenous Heparin after Initial Bolus Dose during Off-Pump Coronary Artery Bypass Surgery: An Eminent Time worthy Study.

Heparin is an anticoagulant used invariably in all cardiac surgery. Heparin dosing and its reversal were determined by monitoring activated clotting time (ACT). Intermittent heparin dosing after initial bolus dose is widely practiced to maintain ACT level 200-300 seconds in Off-pump coronary artery bypass surgery (OPCAB).

Multilevel Mediators on the Associations of Neighborhood Social Environmental Factors and Severity of Metabolic Syndrome: The Jackson Heart Study.

Background: Neighborhood characteristics serve as risk factors for metabolic syndrome (MetS). However, the intermediary factors linking this relationship remain understudied. Thus, we investigated the sex-specific mediating role of C-reactive protein, physical activity (PA), and perceived stress in the associations of perceived neighborhood social environment (PNSE) with MetS severity among Black adults.

Unmasking heavy metal contamination: Tracing, risk estimating and source fingerprinting from coastal sediments of the Payra River in Bangladesh.

The Payra River, cicual for fish breeding, feeding and nursery in coastal Bangladesh, faces heavy contamination from industrial activities, agricultural runoff and poor waste management. This study used ICP-MS to assess metal contamination levels, risk status and potential sources in river sediment. The findings showed that the mean concentrations (mg/kg) of metals followed the decreasing order: Mn (434.

Transdermal Insulin Delivery Using Ionic Liquid-Mediated Nanovesicles for Diabetes Treatment.

Transdermal insulin delivery is a promising method for diabetes management, providing the potential for controlled, sustained release and prolonged insulin effectiveness. However, the large molecular weight of insulin hinders its passive absorption through the stratum corneum (SC) of the skin, and high doses of insulin are required, which limits the commercial viability. We developed ethosome (ET) and -ethosome (TET) nanovesicle formulations containing a biocompatible lipid-based ionic liquid, [EDMPC][Lin], dissolved in 35% ethanol.

Ecological risk assessment of oil & grease (OG) and heavy metals in the surface water of Naf River, Bangladesh.

This study aims to fill the gap in our understanding of the distribution and ecological risk of oil and grease (OG) and toxic heavy metals in the surface water of the Naf River, a major transportation route connecting Teknaf to Saint Martin's Island in Bangladesh. Altogether, 6 sampling stations in this river were assessed for OG and heavy metal pollution, revealing the presence of both at each station. The OG concentration is found ranging from 3.

A simple analytical method for simultaneous determination of currently used pesticide (CUP) residue in river water using LC-MS/MS.

Pesticide residue monitoring in river water is obligatory for their negative ecotoxicological consequences. The current-use pesticides (CUPs) include a diverse range of synthetic pesticides registered by regulatory bodies worldwide as an alternative to the banned organochlorine pesticides (OCPs). Nowadays, CUPs are preferred for agricultural and non-agricultural purposes due to their low persistence and moderate toxicity.

Biological implications of decoding the extracellular matrix of vulva cancer.

The present review aimed to elucidate the roles of extracellular matrix (ECM) components in the progression of vulvar squamous cell carcinoma (VSCC) and explore potential therapeutic avenues for this type of malignancy. This exploration holds promise for identifying precise molecular targets within the ECM milieu, thus facilitating the development of innovative therapeutic modalities tailored to disrupt these interactions and ultimately improve patient outcomes in VSCC. The dysregulated ECM serves as a potent driver of SCC tumor progression, orchestrating key processes such as angiogenesis, inflammation and stromal cell behavior.

Tailoring osteoimmunity and hemostasis using 3D-Printed nano-photocatalytic bactericidal scaffold for augmented bone regeneration.

Bone hemorrhage, infection, and large bone defects following surgical treatment of traumatic bone injury have raised potential concerns, underscoring the urgent need to develop multifunctional therapeutic platforms that can effectively address traumatic bone regeneration. Advancements in three-dimensional (3D) printing technology have propelled the development of several engineering disciplines, such as tissue engineering. Nevertheless, 3D-printed frameworks with conventional materials often lack multifunctional capabilities to promote specific activities for diverse regeneration purposes.

Green solution for oil spills: A review on the role of surface-active ionic liquids.

Oil spills have long-lasting and harmful impacts on the environment, particularly on aquatic ecosystems. This review provides a comprehensive overview of conventional methods for oil spill removal, highlighting both their advantages and limitations. Traditional methods for addressing oil spills, including physical, thermal, biological and chemical techniques, often prove insufficient, with chemical dispersants being the most popular approach.

Understanding the Occurrence and Fate of Atmospheric Microplastics and Their Potential Risks to Human Health: Protocol for a Cross-Sectional Analysis.

Background: Plastic pollution has reached an alarming magnitude, defining the contemporary era as the "Plastic Age." Uncontrolled plastic production and inadequate recycling processes have led to widespread contamination of the environment with micro and nanoplastics.

Objective: The study aims to assess the environmental and human health consequences of exposure to microplastic particles (MPs) and their additives among plastic recycling workers in Dhaka.

Correction: Arbi et al. Polypyrrole-Assisted Ag Doping Strategy to Boost Co(OH) Nanosheets on Ni Foam as a Novel Electrode for High-Performance Hybrid Supercapacitors. 2022, , 3982.

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Heavy metals in commonly consumed rice grains in Bangladesh and associated probabilistic human health risks.

Food contamination by heavy metals is a concerning issue worldwide. The presence of elevated levels of heavy metals in commonly consumed rice has emerged as a critical issue in ensuring food safety. This research encompassed the collection of 44 rice samples, representing seven distinct varieties, through a randomized sampling approach across various retail markets within Dhaka city.

Neuroprotective effect of neuron-specific deletion of the C16 ceramide synthetic enzymes in an animal model of multiple sclerosis.

Ceramide C16 is a sphingolipid detected at high levels in several neurodegenerative disorders, including multiple sclerosis (MS). It can be generated de novo or from the hydrolysis of other sphingolipids, such as sphingomyelin or through the recycling of sphingosine, in what is known as the salvage pathway. While the myelin damage occurring in MS suggests the importance of the hydrolytic and salvage pathways, the growing interest on the importance of diet in demyelinating disorders, prompted us to investigate the involvement of de novo ceramide C16 synthesis on disease severity.

Green metal nanotechnology in monogastric animal health: current trends and future prospects - A review.

Green nanotechnology is an emerging field of research in recent decades with rapidly growing interest. This integrates green chemistry with green engineering to avoid using toxic chemicals in the synthesis of organic nanomaterials. Green nanotechnology would create a huge potential for the use of nanoparticles for more sustainable utilization in improving animal health.

A Case of Emergency Pericardial Drainage for Cardiac Tamponade Due to Dengue Fever.

Dengue fever is a febrile viral disease transmitted by mosquitoes. The symptoms of dengue fever are numerous and varied; however, cardiac tamponade is a particularly rare and atypical complication. This study describes a case of a 30-year-old male who presented with acute respiratory distress and chest pain on the ninth day after diagnosis of dengue fever.

Environmental and human health risk of potentially toxic metals in freshwater and brackish water Nile tilapia (Oreochromis niloticus) aquaculture.

Tilapia aquaculture is rapidly expanding worldwide, particularly in Bangladesh. However, metal pollution in aquaculture presents significant environmental and human health risks. This study aimed to evaluate the concentrations of 13 potentially toxic metals (As, Be, Cd, Co, Cr, Cu, Hg, Ni, Pb, V, Mn, Se, and Zn) in Nile tilapia (Oreochromis niloticus), surface water, and sediment from freshwater and brackish water aquaculture ponds.

Effectiveness of a Single Intra-articular Injection of High-Molecular-Weight Hyaluronic Acid Versus NSAIDs on the Visual Analog Pain Scale and Western Ontario and McMaster Universities Osteoarthritis Index Scores in Patients With Knee Osteoarthritis.

Objective: This study aimed to determine the effectiveness of a single intra-articular injection of high-molecular-weight (HMW) hyaluronic acid (HA) at a dose of 4 mL/60 mg to reduce pain in people with knee osteoarthritis (OA) over 12 months.

Methodology: This retrospective study was conducted after obtaining ethical approval from Dhaka Medical College and Hospital, Bangladesh. From July 2020 to June 2021, a medical professional conducted the investigation.

A comparative study of the elevated radioactivity in beach placer deposits of Bangladesh.

Beach sediments are mineral deposits formed through weathering and erosion of either igneous or metamorphic rocks. Among the rock constituent minerals are some natural radionuclides that contribute to ionizing radiation exposure on Earth. Kolatoli and Kuakata are the two major beaches with heavy mineral deposits and important tourist sites in Bangladesh.

Mobilization mechanisms and spatial distribution of arsenic in groundwater of western Bangladesh: Evaluating water quality and health risk using EWQI and Monte Carlo simulation.

Arsenic (As) contamination in groundwater is emerging as a significant global concern, posing serious risks to the safety of drinking water and public health. To understand the release mechanisms, mobilization processes, spatial distribution, and probabilistic health risks of As in western Bangladesh, forty-seven samples were collected and analyzed using an atomic absorption spectrometer (AAS). The As concentrations in groundwater ranged from 1.