Curcumin-capped gold nanorods as optical sensing platform for sequence specific detection of DNA based on their self-assembly.

We are reporting curcumin-induced gold nanorods as an optical sensing platform for the detection of sequence-specific DNA target through their self-assembly. The combined effect of eco-friendly reducing agent (i.e.

Immediate Response of Diode Laser on the Microbial Load in Subjects with Chronic Periodontitis.

Background: Chronic periodontitis is the most common dental disease reported globally as well as in India. Periodontal pathogens are usually seen in samples of gingival tissues, crevicular blood, GCF (gingival crevicular fluid), and dental plaque. Apart from the conventional mechanical treatment, laser disinfection is a recent advancement that change shows greater efficacy in reducing the disease progression and changing the bacterial flora.

Flaxseed oil modulates testicular biometrics, hormone, libido, antioxidant and semen profiles in endangered Teressa goat of Andaman and Nicobar Islands.

Teressa goat is a unique goat breed in Andaman and Nicobar Islands (ANI) of India. Effects of Flaxseed oil (FSO) supplementation in body weight (BW), scrotal circumference (SC), testicular volume (TV) and testicular weight (TW), endocrinological profiles, sex behavioural profiles (SBPs), oxidative stress markers and semen production and its quality profiles in rainy and dry summer season were studied in Teressa goat. Male goats (n = 12) of 3-4 years old were equally divided into control and treated groups.

Fluorescent copper conjugated curcumin cysteine nanoprobe for selective determination of Fe and G-quadruplex DNA.

The synthesis of fluorescent copper-curcumin-cysteine (Cu-CC) as a sensing platform is reported. The synthesized probe has been confirmed by UV-visible spectroscopy, FT-IR, XRD, SEM, and TEM characterization techniques, respectively. The mechanistic aspects of selective sensing of Fe and detection of different G-quadruplex DNA have been illustrated based on the "turn-off-on" concept of a regeneratable fluorescence sensing probe at λ 450 nm.

Late toxicity within a Phase III clinical trial of IG-IMRT in cervix cancer (PARCER): Reanalysis with time weighted adverse event reporting (MOSES).

Background And Purpose: This post-hoc analysis was performed to report the impact of Image guided intensity modulated radiotherapy (IG-IMRT) and three-dimensional conformal radiotherapy (3D-CRT) across organ system and grades of toxicity within PARCER trial (NCT01279135). Primary endpoint of PARCER focused on grade ≥ 2 late gastrointestinal (GI) toxicity using Common Terminology Criteria for Adverse Events (CTCAE). We now analyze all adverse events using CTCAE and time and severity weighted toxicity reporting method (MOSES).

Success of Dental Implant Influenced by Abutment Types and Loading Protocol.

Background: Dental implants are considered better, latest, and most advanced technique of teeth replacement in present times with more teeth loss and increased related concerns.

Aims: The present clinical trial was carried out to assess marginal bone loss and implant failure in immediate and delayed loading implants. The study also evaluated healing using Polymerase Chain Reaction (PCR) and the effect of risk factors on marginal bone loss.

Pigeon Inspired Optimization with Encryption Based Secure Medical Image Management System.

Presently, technological advancements in the healthcare sector pose a challenging problem relevant to the security and privacy of health-related applications. Medical images can be considered significant and sensitive data in the medical informatics system. In order to transmit medical images in an open medium, the design of secure encryption algorithms becomes essential.

NK1 receptor antagonistic effect of 17-trifluoromethyl phenyl trinor prostaglandin F2α on the growth of human breast cancer cell line.

Background: A growing number of genetic and cancer biology investigations have found that the tachykinin NK1 Receptor plays an important role in cancer cell proliferation and survival. In this study. The present study was designed to evaluate the inhibition of cell growth by 17-trifluoromethyl phenyl trinor prostaglandin F2α with NK1 receptor in breast cancer cell lines.

Hydrothermal liquefaction of Prosopis juliflora biomass for the production of ferulic acid and bio-oil.

The objective of this work was to study the hydrothermal liquefaction (HTL) of Prosopis juliflora biomass for the production of ferulic acid and bio-oil. Biomass was processed with various solvents (NaOH, KOH, HCl and HSO) to produce ferulic acid (FA). FA oxidation was carried out using the Nano ZnO catalyst to produce an optimum vanillin yield of 0.

Improved Electrical Wiring of Glucose Oxidase Enzyme with an Immobilized Mn(1,10-Phenanthroline)Cl-Complex/Multiwalled Carbon Nanotube-Modified Electrode Displaying Superior Performance to Os-Complex for High-Current Sensitivity Bioelectrocatalytic and Biofuel Cell Applications.

The search for a new and efficient transducer that can electrically connect enzyme active sites, like flavin adenine dinucleotide in glucose oxidase (GOx), with the electrode surface is a cutting-edge research area. Currently, Os(bpy)-complex pendent polyvinylpyridine/polyvinyl imidazole/pyridinium hydrogel based chemically modified electrodes have been widely used for this purpose (bpy = 2,2'-bipyridine). Herein, we report, a [Mn(phen)(O)(Cl)] complex/Nafion-immobilized carboxylic acid-functionalized multiwalled carbon nanotube modified glassy carbon electrode (GCE/f-MWCNT@Mn(Phen)O(Cl)-Nf, phen = 1,10-phenanthroline), prepared by an electrochemical method using the precursor, Mn(phen)Cl, as an efficient and low cost alternate to the Os-complex transducer, for the glucose oxidase enzyme (GOx) based bio-electro-catalytic system.

An electrochemical immunosensor for efficient detection of uropathogenic E. coli based on thionine dye immobilized chitosan/functionalized-MWCNT modified electrode.

Uropathogenic Escherichia coli (UPEC) is the major cause of 150 million Urinary Tract Infections (UTI) reported annually world-wide. High prevalence of multi-drug-resistance makes it dangerous and difficult to cure. Therefore simple, quick and early diagnostic tools are essential for effective treatment and control.

Effect of photografting 2-hydroxyethyl acrylate on the hemocompatibility of electrospun poly(ethylene-co-vinyl alcohol) fibroporous mats.

Poly(ethylene-co-vinyl alcohol) (EVAL) has been recommended as a material suitable for blood contacting applications. Effect of ethylene content and associated hydrophobicity of EVAL on the blood-material interactions have been documented in the literature. In this work, surface chemistry of EVAL substrate was altered by photografting a hydrophilic monomer, 2-hydroxyethyl acrylate (HEA) with the aid of a photoinitiator, benzophenone (BP), and the effect of surface modification on the blood-material interactions was investigated.

In Situ Derivatization of an Intrinsic Iron Impurity as a Surface-Confined Iron(II)tris(2,2'-bipyridine) Complex on MWCNT and Its Application to Selective Electrochemical Sensing of DNA's Purine Bases.

The derivatization of an intrinsic iron impurity in a carbon nanotube (CNT-*Fe, *Fe-intrinsic, and redox-active iron impurity) as a functional molecular system has been challenging to realize. There are certain limitations on the derivatization of such iron impurities such as low concentration and limited accessibility. Herein, we report an in situ electroassisted derivatization of an intrinsic and redox-active iron impurity in a multiwalled carbon nanotube (MWCNT-*Fe, *Fe, 2.

Bovine milk usage and feeding practices for infants in India.

Background: Milk and dairy products from animal sources (cow's milk or buffalo's milk) are an important part of Indian diet and its consumption starts at an early age.

Objective: The purpose of this study is to understand the processing, storage and modifications carried out before bovine milk is fed to the infants and compare it with recommendations by Health Care Professionals (HCPs).

Materials And Methods: The study involved assessments involving HCPs and mothers of children below 1 year of age through both qualitative and quantitative methods.

Employee engagement and job satisfaction in the information technology industry.

Employee engagement has been identified as being important to employee productivity and performance. Measures of employee engagement and job satisfaction in the context of information technology (IT) were developed to explore how employee engagement affects perceived job satisfaction. In a sample of IT professionals (N = 159), controlling for age, sex, job tenure, and marital status, employee engagement had a significant and positive correlation with job satisfaction.

Protein kinase G phosphorylates mosquito-borne flavivirus NS5.

Serine/threonine phosphorylation of the nonstructural protein 5 (NS5) is a conserved feature of flaviviruses, but the kinase(s) responsible and function(s) remain unknown. Mass spectrometry was used to compare the phosphorylation sites of the NS5 proteins of yellow fever virus (YFV) and dengue virus (DENV), two flaviviruses transmitted by mosquitoes. Seven DENV phosphopeptides were identified, but only one conserved phosphoacceptor site (threonine 449 in DENV) was identified in both viruses.

Role for conserved residues of sindbis virus nonstructural protein 2 methyltransferase-like domain in regulation of minus-strand synthesis and development of cytopathic infection.

The plus-strand RNA genome of Sindbis virus (SINV) encodes four nonstructural proteins (nsP1 to nsP4) that are involved in the replication of the viral RNA. The approximately 800-amino-acid nsP2 consists of an N-terminal domain with nucleoside triphosphatase and helicase activities and a C-terminal protease domain. Recently, the structure determined for Venezuelan equine encephalitis virus nsP2 indicated the presence of a previously unrecognized methyltransferase (MTase)-like domain within the C-terminal approximately 200 residues and raised a question about its functional importance.

[Optimal age for gastric cancer screening in patients with dyspepsia without alarm symptoms].

Objective: To determine the optimal age for screening endoscopy on patients with dyspepsia without alarm symptoms to avoid missing gastric cancer.

Methods: A Cross sectional study was performed (2001-2005). 285 cases of patients with dyspepsia and gastric cancer were found at Arzobispo Loayza National Hospital.

Molecular analysis of the dormancy response in Mycobacterium smegmatis: expression analysis of genes encoding the DevR-DevS two-component system, Rv3134c and chaperone alpha-crystallin homologues.

Mycobacteria adapt to a decrease in oxygen tension by entry into a non-replicative persistent phase. It was shown earlier that the two-component system, DevR-DevS, was induced in Mycobacterium tuberculosis and Mycobacterium bovis BCG cultures during hypoxia, suggesting that it may play a regulatory role in their adaptation to oxygen limitation. The presence of a homologous genetic system in Mycobacterium smegmatis was predicted by scanning its unfinished genome sequence with devR and devS genes of M.