Publications by authors named "Maria-Del-Carmen Vega-Menchaca"
Immunomodulatory Activity of Diterpenes over Innate Immunity and Cytokine Production in a Human Alveolar Epithelial Cell Line Infected with .
Curr Mol Pharmacol
May 2023
Article Synopsis
- - The study focuses on three diterpenes from Salvia ballotiflora, evaluating their immunomodulatory effects on innate immunity and cytokine production in human alveolar cells infected with Mycobacterium tuberculosis.
- - Findings indicate that anastomosine and 7,20-dihydroanastomosine significantly boost reactive nitrogen species (RNS) production after 36 hours and reactive oxygen species (ROS) after 12 hours post-treatment, showcasing their potential role in enhancing innate immunity.
- - The diterpenes exhibited an anti-inflammatory effect by modulating TGF-β levels; however, they did not significantly affect TNF-α release, suggesting a selective immune response to the tuberculosis infection.
Dengue fever is a disease with a high mortality rate around the world, which is an important issue for the health authorities of many countries. As a result of this, the search for new drugs that are effective to combat this disease has become necessary. Medicinal plants have been used since ancient times to treat a wide list of diseases, including dengue fever.
View Article and Find Full Text PDFBackground: The COVID-19 pandemic had infected more than 3.5M people around the world and more than 250K people died in 187 countries by May 2020. The causal agent of this disease is a coronavirus whose onset of symptoms to death range from 6 to 41 days with a median of 14 days.
View Article and Find Full Text PDFBackground: Pathogens use multiple mechanisms to disrupt cell functioning in their host and allow pathogenesis. These mechanisms involve communication between the pathogen and the host cell through protein-protein interactions.
Methods: Protein-protein interactions chains referred to as signal transduction pathways are the processes by which a chemical or physical signal transmits through a cell as series of molecular events so the pathogen needs to intercept these molecular pathways at few positions to induce pathogenesis such as pathogen viability, infection or hypersensitivity.
EVALUATION OF THE CHELATING EFFECT OF METHANOLIC EXTRACT OF AND ITS FRACTIONS ON WISTAR RATS POISONED WITH LEAD ACETATE.
Afr J Tradit Complement Altern Med
August 2017
Background: The rate of lead poisoning has decreased in recent years due to increased health control in industries that use this metal. However, it is still a public health problem worldwide. The use of various plants with chelating properties has been a topic of research today.
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