[Carney's complex (myxomas, pigmented spots and endocrine hyperactivity). Apropos of a partial form in monozygotic twins].

The authors describe monozygotic twins with right ventricular myxoma, one of whom had cutaneous myxomas, large cell calcifying Sertoli cell tumor of the testis (a lesion which was certainly latent in his brother) and recurrent cardiac myxoma. These elements are manifestations of "Carney's complex". This recently reported inherited syndrome should be recognized by pathologists because of major risk of cardiac myxoma.

[Recurrent polychondritis with renal microaneurysms and segmental necrotizing glomerulonephritis].

The authors report a case of relapsing polychondritis, in a 41 year-old man, with renal complication. Immunofluorescence study of this segmental necrotizing glomerulonephritis showed an important fibrin fixation without immunoglobulins. Selective renal arteriography, preliminary to the biopsy, showed lobular arterial aneurysms.

[Bronchopulmonary manifestations of Horton's disease. Apropos of a case].

A 78 years old woman developed a pulmonary recurrence four years after the diagnosis of temporal arteritis. The lung biopsy showed the same giant-cells granulomatous lesions with central vessels as the initial biopsy. The recurrence in giant cells-arteritis has already been published but the pulmonary involvement had never been illustrated before by histological data.

[Silicone deposits in macrophages of patients on chronic hemodialysis].

A retrospective study was carried out in search of silicone deposits in 11 periodic hemodialysis patients (1 liver biopsy, 4 splenectomies and 6 autopsies) treated between 12 and 60 months with equipment containing a silicone pump segment. Silicone particles were found in the macrophage cells of all patients, especially in the liver and spleen, but also in lymph nodes, bone marrow and even an artery wall. In some cases, macrophage response had formed sarcoid-like granulomas.

[Anatamo-pathologic aspects of gold-salt induced cholestasis. Report of two cases with ultrastructural study (author's transl)].

The authors report two cases of gold-salt-induced cholestasis. They make a review of the thirteen cases previously related in the literature ; the cholestasis was constant, the hepatocytic necrosis was unusual and the gold-salts were difficult to visualize in the liver biopsy and more especially at the ultrastructural level. The immunological mechanism of hypersensibility is well established ; the possibility of an associated hepatotoxicity is debated.

[A case of relapsing mesenchymatous tumour of the abdominal wall with metastases (author's transl)].

It is classical to consider desmoid tumours as an entity with only a local prognosis, conditioned by the frequency of relapses. In this respect, they are different from other mesenchymatous tumours, fibrosarcomas in particular which have a poorer prognosis. The authors report the case of a 23 years old man with a tumour of the abdominal wall, which in the early stages resembled a desmoid tumour, but the development of metastases suggested a sarcoma.

[Myxoma of the right ventricle in monozygotic twins: surgical ablation].

Monozygotic twins aged 23 underwent surgery, at an interval of 4 months from each other, for a myxomatous tumour of the right ventricle which had been completely asymptomatic until then. The authors present the clinical, electrocardiographic and angiographic findings, together with details of the operation and of the histological findings. They recall how rare a site this is, and summarise some of the observations which have been made on familial myxomas.

[Vascular lesions of Fabry's disease. Optical, histochemical and ultrastructural studies].

On the basis of a new case of Fabry's disease and the various cases published in the literature, the authors analyse the vascular lesions of this angiodysplasia related to an error in lipid metabolism. They emphasise the involvement of lymph vessels (in particular those of the small bowel), and the ultrastructural characteristics and the mode of formation of deposits within the endothelial cells of the vascular walls.

[Anatomopathologic study of 54 cases of diffuse pleural mesothelioma found in the harbor regions of Nantes, Saint-Nazaire and Lorient].

The study concerned the macroscopic and microscopic examination of 54 cases of diffuse malignant mesothelioma. Four points were felt to be of interest and worthy of emphasis: --the unilateral nature of the lesions, constant in this series; --the absence of involvement of other serous surfaces; --the tumour-like appearance of the disorder in 2/3 of cases and the appearance of a simple pachy-pleuritis in 1/3; --from a histological standpoint, despite the morphological flexibility of the classically accepted mesothelial cells, the homogenicity of our group, in which tumour morphology was much more epithelial than histiocytic or connective.