Topology synthesis of coupled inductor based four port DC-DC converter for multi-input PV-battery application with autonomous mode selection.

Multiport converters are the most reliable and integral component for latest renewable source integration with multiple inputs. This article is one among the kind, which proposes a novel Coupled Inductor based Four Port topology Multiport Converter (CI-FP-MPC) for integrating multiple PV sources with different voltages. The adoption of coupled inductor contributes an increased voltage gain with reduced stress on the switches and diodes.

An efficient combined intelligent system for segmentation and classification of lung cancer computed tomography images.

Background And Objective: One of the illnesses with most significant mortality and morbidity rates worldwide is lung cancer. From CT images, automatic lung tumor segmentation is significantly essential. However, segmentation has several difficulties, such as different sizes, variable shapes, and complex surrounding tissues.

Enhanced resolution of optical genome mapping utilizing telomere-to-telomere reference in genetic disorders.

Reference genomes serve as a baseline criterion for comparison of personal genomes to deduce clinical variants. The widely used reference genome, GRCh38, contains stretches of gaps and unresolved bases particularly in complex regions which could obscure variant discovery. In contrast, the gapless telomere-to-telomere CHM13 (T2T-CHM13) reference genome can be used to assess difficult regions of the genome.

Probiotics, tetracycline fibres and chlorhexidine gel's effectiveness in treating chronic periodontitis as a supplement to scaling and root planning.

A periodontal pocket can result into progressive loss of attachment. Many agents are tried to improve periodontal health. Hence this research was done to estimate the effectiveness of Tetracycline fibers; Probiotics and Chlorhexidine gel as a conjunction to scaling and root planning (SRP) in the treatment of chronic periodontitis.

Normative Data of Carpal Bone Measurements in the Sample Adult Indian Population.

 Radiography is the most often accessible and affordable imaging modality. Accurate assessments of wrist X-rays can aid in the diagnosis and prognostic evaluation of various wrist problems. This study aims to identify normal radiographic anthropometry reference values and variations of carpal bones and joints by gender and age in sample Indian population, with the potential to be clinically applicable.

Modulating Coagulation via Bioinspired Mesoporous Calcium-Decorated Silica Nanoparticles for Efficient Fibrin Clot Formation.

Blood clotting is vital for preventing bleeding after an injury. Hemostasis is a complex cascade involving numerous plasma proteins. Uncontrolled bleeding leads to mortality.

Awareness About Noise Induced Hearing Loss and the Use of Unsafe Listening Practices Among Medical Students.

To assess the Knowledge, Attitude, and Practice on Noise Induced Hearing Loss(NIHL) caused by using Personal Listening Devices (PLD). To assess the usage pattern of PLD among undergraduate medical students studying at a tertiary health center in South India. A descriptive study was conducted by the Department of ENT over a three-month duration on undergraduate medical students who volunteered to fill in an electronic questionnaire form that they received via WhatsApp.

Vaginal Delivery in a Tracheostomised Woman: A Rare Case Scenario.

Spontaneous vaginal delivery in a tracheostomised woman is rare and literature concerning the same is also very limited, hence this might help in considering vaginal delivery at term as an option in such patients when there are no medical or obstetrical contraindications for the same. We present a case of a 24 years female patient hailing from Tamil Nadu in South India, who was tracheostomised secondary to subglottic stenosis, presented to Otorhinolaryngology department at thirty-eight weeks of gestation to know the possibility of a vaginal delivery at term. Since the patient had an uneventful obstetrical history and no medical or obstetrical contraindications for a vaginal delivery, patient was advised breathing exercises including Valsalva manoeuvre and kept under close follow up.

Significance of Nestin and CD133 as cancer stem cell markers in diffuse glioma and association with p53 expression and IDH status.

Background: Recent evidence suggests that the tumor stem cells that are responsible for the pathogenesis of gliomas have similar properties to those of neural stem cells. We have studied two of the most consistently expressed stem cell markers in gliomas, i.e.

Monodigital Double Cross-Finger Flaps-A Novel Approach for Coverage of Large Volar Defects.

Introduction: A single cross-finger flap can only address digital defects of a limited size, and larger defects often require distant flaps such as abdominal or groin flaps that are cumbersome to perform and sometimes bulky. Two cross-finger flaps harvested from the same donor digit could offer a simple and effective solution for many such defects. In this study, we describe the technique of monodigital double cross-finger flaps and its clinical applicability, with evaluation of donor and recipient site morbidity.

Criteria for Determining Hearing Disability: A Narrative Review of Global Perspective.

Hearing loss is a highly prevalent condition worldwide, affecting over 5% of the global population. Determining disability and eligibility for rehabilitation services due to hearing loss is complex, as countries employ differing audiometric criteria and methods. This report reviews current literature on audiometric thresholds used globally to determine hearing disability, highlighting challenging cases worldwide.

Clinico-microbiological Profile and Outcomes of Asymptomatic Bacteriuria in Pregnancy.

Background: Asymptomatic bacteriuria (ASB) during pregnancy can lead to symptomatic urinary tract infection (UTI), with increased fetal and maternal morbidity and mortality. We evaluated the incidence, clinical and microbiological profile, and outcome of ASB in pregnant women attending our antenatal clinic.

Materials And Methods: This prospective study was conducted on 3769 pregnant women in a routine antenatal clinic at a tertiary care center.

A randomized controlled trial of medication adherence and management of risk factors for secondary prevention of stroke (MaMoRS) using a smartphone-based application.

Background: There are little data on the use of smartphone-based applications for medication adherence and risk-factor control for the secondary prevention of stroke in low-and-middle-income countries (LMICs).

Aims: The aim was to determine whether a smartphone-based app improved medication adherence, risk-factor control, and provided health education to stroke survivors for lifestyle and behavioral modifications.

Methods: An unblinded, single-center randomized controlled double arm trial with 1:1 allocation among stroke survivors was performed in South India.

Triclosan, an antimicrobial drug, induced reproductive impairment in the freshwater fish, (Bloch, 1792).

Triclosan (TCS), an antimicrobial drug, is known to occupy different compartments in aquatic ecosystems. The present study focused to evaluate the reproductive toxicity of triclosan, at environmentally relevant (0.009 and 9 μg L) and sublethal (176.

Visual interpretation of clinical images among dental students using eye-tracking technology.

Background: Tele-consultations are increasingly used for screening and diagnosis. Only a few studies have assessed dental students' visual attention to clinical images.

Aim: To (i) determine dental students' gaze behavior, visual fixations, and diagnostic competence while viewing clinical images, and (ii) explore potential opportunities to strengthen the teaching-learning approaches.

Beyond the Norm: Tracheostomy's Vital Role in Unconventional Foreign Body Removal.

Background: Foreign Body Aspiration (FBA) is one of the paediatric emergencies which require timely diagnosis and management. The inherent tendency of children to explore small objects with their mouths often prove to be fatal as they are difficult to remove once aspirated.

Case Report: We present the case of a 5-year-old boy who presented with dyspnea and vomiting following the aspiration of a pen cap.

Digital Health Literacy: Evaluating the Readability and Reliability of Cochlear Implant Patient Information on the Web.

Hearing aids and implants are used to treat hearing loss, with cochlear implants being the most successful option for severe sensorineural hearing loss. Patients frequently use the internet as a trusted source of clinical information before committing to any therapeutic procedure, including receiving a cochlear implant. A health resource's readability and dependability influence its value to patients.

Radiological Parameters Predicting the Round Window Niche Visibility through Facial Recess Approach in Cochlear Implantation.

Aim: The aim was to study the radiological parameters using High Resolution Computed Tomography (HRCT) temporal bone to predict the Round Window Niche (RWN) visibility through the facial recess approach and to study radiological types of the round window niche.

Materials And Methods: Prospective study was done in the patients underwent CI surgery from 2019 to 2021. HRCT radiological parameters of the patients and their intraoperative visualisation from video recordings were compared to predict the most feasible parameters to predict good visualisation of RWN.

Ear Mites as an Overlooked Source of Ear Itching and Tinnitus - A Case Series.

Otoacariasis is a rare condition characterized by ticks and mites in the ear canal. Human otoacariasis remains underrepresented in literature as otoacariasis is more common in animals. Systemic diseases being transmitted by these arachnids pave the way for potential complications.

Tumor histoculture captures the dynamic interactions between tumor and immune components in response to anti-PD1 in head and neck cancer.

Dynamic interactions within the tumor micro-environment drive patient response to immune checkpoint inhibitors. Existing preclinical models lack true representation of this complexity. Using a Head and Neck cancer patient derived TruTumor histoculture platform, the response spectrum of 70 patients to anti-PD1 treatment is investigated in this study.

Assessment of medication discrepancy, medication appropriateness, and cost analysis among patients with pediatric nephrotic syndrome: An ambispective cohort observational study.

Background: Nephrotic syndrome (NS) is a commonly encountered chronic kidney disease in pediatric populations, with South Asian children being at high risk and requiring long-term pharmacological management. Thus, identifying medication discrepancies and evaluating the appropriateness of therapy and its economic burden are vital for inpatient management. The aim of the study was to assess medication reconciliation, medication appropriateness, and cost analysis in NS cases.