Publications by authors named "Kristiningrum"

Research Background: Fish freshness and quality monitoring are of high importance for consumers, retailers and fishing industry. Therefore, developing novel approaches that are simple, fast, non-destructive and inexpensive to monitor fish freshness in real time is of great value. One alternative is using Intelligent or smart packaging to monitor the freshness or conditions of packaged fish.

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Microorganisms in nature are highly diverse biological resources, which can be explored for drug discovery. Some countries including Brazil, Columbia, Indonesia, China, and Mexico, which are blessed with geographical uniqueness with diverse climates and display remarkable megabiodiversity, potentially provide microorganismal resources for such exploitation. In this review, as an example of drug discovery campaigns against tropical parasitic diseases utilizing microorganisms from such a megabiodiversity country, we summarize our past and on-going activities toward discovery of new antimalarials.

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One of the important issues in standard implementation is its economic impact. This is because the economic benefits of the standard implementation are intangible and difficult to be measured. Therefore, this research aims to analyze the economic benefit of standard implementation in Indonesian auto - electric stove for SME by using the economic benefit of standard (EBS) approach developed by ISO.

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Article Synopsis
  • - Two Indonesian fungi, *Aspergillus assiutensis* and *Penicillium pedernalense*, along with a Japanese fungus, *Hypomyces pseudocorticiicola*, have been identified as producers of gentisyl alcohol, a compound that inhibits the enzyme PfDHODH associated with the malaria parasite.
  • - Gentisyl alcohol has a strong inhibitory effect on PfDHODH, with a half-maximal inhibitory concentration (IC) value of 3.4 μM, indicating its potential as an anti-malarial agent.
  • - Another Indonesian fungus, *Penicillium citrinum*, produces homogentisic acid, which is a less effective analog of gent
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Article Synopsis
  • Researchers isolated a fungus called Talaromyces pinophilus to discover new inhibitors for an enzyme (PfDHODH) linked to the malaria-causing parasite Plasmodium falciparum.* -
  • The main compound identified, altenusin, inhibited PfDHODH with a potency of 5.9 μM, and other metabolites, mitorubrinol and mitorubrinic acid, also showed inhibitory effects.* -
  • While compounds 1 and 2 effectively targeted PfDHODH and hindered parasite growth, they did not affect the human version of the enzyme, whereas compound 3 had minimal inhibitory properties.*
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The mangrove forests in Balikpapan Bay, Indonesia, have been used as a source of livelihood for local community more than 150 years. Since the natural products of the mangrove forest, such as wood and seafood, are not able to meet the economic needs of the local community, some areas have been converted into brackish water ponds with traditional aquaculture systems. The growth of brackish water ponds over the last five decades has been identified as the main cause of ecosystem destruction.

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