Synthesis and characterization of novel guar gum based waste material derived nanocomposite for effective removal of hexabromocyclododecane and lindane.

Herein, efficient degradation of hexabromocyclododecane (HBCD) and Lindane, a persistent organic pollutant using guar gum based calcium oxide doped silicon dioxide (GG-CaO@SiO) has been reported. The nanocomposite was prepared by waste egg shell (CaO) and rice husk (SiO) was well characterized. The maximum degradation of HBCD and Lindane were observed at 8 mg catalyst loading, neutral pH, and 2 mg L of pollutant amount.

Green construction of biochar@NiFeO nanocomposite for highly efficient photocatalytic remediation of pesticides from agriculture wastewater.

The world's attention is drawn to the widespread ingestion, toxicity, and bioaccumulation of the Atrazine (AT) and Endosulfan (ES). Pesticides have been proven to have endocrine-disrupting, genotoxic, and persistent characteristics. In this work, the structural design of green synthesized NiFeO is incorporated in rice husk biochar to form BC@NiFeO nanocomposite.

One pot green synthesis of Al doped zinc ferrite nanoparticle decorated with reduced graphene oxide for photocatalytic remediation of organic pollutants: Green synthesis, kinetics, and photoactivity.

The world is drawn to the widespread use, toxicity, and bioaccumulation of the Atrazine (AT) and Auramine O (AO). Pesticides and dyes also have endocrine disruptors, genotoxic and persistent properties. Therefore, the photodegradation of AT and AO in water was investigated.

An updated review on environmental occurrence, scientific assessment and removal of brominated flame retardants by engineered nanomaterials.

Due to the extensive manufacturing and use of brominated flame retardants (BFRs), they are known to be hazardous, bioaccumulative, and recalcitrant pollutants in various environmental matrices. BFRs make flame-resistant items for industrial purposes (textiles, electronics, and plastics equipment) that are disposed of in massive amounts and leak off in various environmental matrices. The consumption of plastic items has expanded tremendously during the COVID-19 pandemic which has resulted into the increasing load of solid waste on land and water.

The Role and Mechanism of CREBH Regulating SIRT3 in Metabolic Associated Fatty Liver Disease.

Aims: To investigate the effect of cAMP response element-binding protein H (CREBH) on metabolic associated fatty liver disease by regulating sirtuin 3 (SIRT3).

Main Methods: Two mouse models of fatty liver induced by a methionine-choline deficient (MCD) diet and a high-fat (HF) diet and an in vitro model of palmitic acid (PA) induced lipid-overloaded hepatocytes were constructed to detect the expression of CREBH, SIRT3, total acetylation, and downstream protein interactions and lipid metabolism phenotype, which were further validated in CREBH mice and lentivirus-overexpressing CREBH hepatocytes.

Key Findings: In fatty liver and lipid overload models, the expressions of CREBH and SIRT3 were down-regulated and their expression was positively correlated, accompanied by an increase in the level of total protein acetylation.

Efficient removal of plastic additives by sunlight active titanium dioxide decorated Cd-Mg ferrite nanocomposite: Green synthesis, kinetics and photoactivity.

Large use of flame retardants or additives in plastic industries have caused scientific attention as their leaching from consumer products is indicative of environmental concern. Moreover, plastic additives have proven features of endocrine disruptors, genotoxicity and persistence. Therefore, photodegradation of tetrabromobisphenol A (TBBPA) and bisphenol A (BPA) were explored in water.

Efficient degradation of organic pollutants by novel titanium dioxide coupled bismuth oxide nanocomposite: Green synthesis, kinetics and photoactivity.

Herein, a green and facile methodology was used for the structural design of semiconductor nanomaterials and employed as efficient photocatalyst to resolve the environmental issues of water pollutants. Titanium oxide coupled with bismuth oxide (TiO@BiO) nanocomposite was synthesized by employing the seed extract of Sapindus mukorossi (commonly found plant in India) and subsequently used for the elimination of toxic, and persistence industrial pollutants namely bisphenol A (BPA) and methylene blue (MB). Microscopic and spectroscopic techniques revealed particle size of synthesized nanocomposite found less than 50 nm along with high crystallinity.

Sunlight-induced photocatalytic degradation of organic pollutants by biosynthesized hetrometallic oxides nanoparticles.

Dyes and phenols are extensively used chemicals in petrochemicals, pharmaceuticals, textile, and paints industries. Due to high persistence, bioaccumulation, and toxicity, their removal from the environment is highly imperative by advanced techniques. Single metal oxide nanomaterials are generally associated with limitations of large bandgap (> 3eV) and charge recombination.

Green synthesis of sunlight responsive zinc oxide coupled cadmium sulfide nanostructures for efficient photodegradation of pesticides.

Structural design of semiconductor nanomaterials via facile and green methodology is noteworthy to advance their photocatalytic activity for resolving the problem of energy and environment. Herein, sunlight active zinc oxide coupled with cadmium sulfide (ZnO@CdS) was synthesized by employing the leaf extract of Azadirachta indica. Subsequently, it was used for removal of chlorpyrifos (CP) and atrazine (Atz) pesticides that have shown high persistence, bioaccumulation, and toxicity in the environment.

A New Crystal Form of the SARS-CoV-2 Receptor Binding Domain: CR3022 Complex-An Ideal Target for In-Crystal Fragment Screening of the ACE2 Binding Site Surface.

In-crystal fragment screening is a powerful tool to chemically probe the surfaces used by proteins to interact, and identify the chemical space worth exploring to design protein-protein inhibitors. A crucial prerequisite is the identification of a crystal form where the target area is exposed and accessible to be probed by fragments. Here we report a crystal form of the SARS-CoV-2 Receptor Binding Domain in complex with the CR3022 antibody where the ACE2 binding site on the Receptor Binding Domain is exposed and accessible.

Mining the PDB for Tractable Cases Where X-ray Crystallography Combined with Fragment Screens Can Be Used to Systematically Design Protein-Protein Inhibitors: Two Test Cases Illustrated by IL1β-IL1R and p38α-TAB1 Complexes.

Nowadays, it is possible to combine X-ray crystallography and fragment screening in a medium throughput fashion to chemically probe the surfaces used by proteins to interact and use the outcome of the screens to systematically design protein-protein inhibitors. To prove it, we first performed a bioinformatics analysis of the Protein Data Bank protein complexes, which revealed over 400 cases where the crystal lattice of the target in the free form is such that large portions of the interacting surfaces are free from lattice contacts and therefore accessible to fragments during soaks. Among the tractable complexes identified, we then performed single fragment crystal screens on two particular interesting cases: the Il1β-ILR and p38α-TAB1 complexes.

Cathodoluminescence investigation of residual stress in Er3+:YAlO3 thin films grown on (110) SrTiO3 substrate by metal-organic chemical vapor deposition.

YAlO3 thin films doped with different amounts of Er3+ have been grown directly onto (110) SrTiO3 substrate using the metal-organic chemical vapor deposition method (MOCVD). X-ray diffraction patterns and the rocking curve of the (002) reflection point to the growth of <001>-oriented YAlO3 phase. Piezo-spectroscopic (PS) biaxial calibration was performed on two luminescence bands, related to transitions from the (4)S3/2 excited state, using a specially designed ball-on-ring loading jig.

Complex optical field reconstruction by separating the Fourier spectrum.

A complex optical field in a Fourier plane is experimentally recovered by separating the real and imaginary parts of the Fourier spectrum in real time without an additional inverted object function U(-x, -y), and the signs of both parts are derived by differentiating the real spectrum.