Purpose: The purpose of this study was to analyze choroidal thickness (CT), along with macular thickness (MT), peripapillary retinal nerve fiber layer thickness (RNFLT), and macular vascular density (MVD) using swept-source optical coherence tomography (SS-OCT) in children with unilateral amblyopia, and compare the same with normal fellow eyes and normal eyes of normal children before and following occlusion therapy.
Materials And Methods: This was a prospective, longitudinal study of 60 children (4-18 years); 30 children had unilateral amblyopia and remaining 30 were normal. Group 1 consisted of 30 amblyopic eyes of children with unilateral amblyopia; Group 2 consisted of 30 fellow normal eyes of Group 1; Group 3 consisted of normal eyes of normal children.
Despite the recent advances in vaccination and treatment strategies, cervical cancer continues to claim numerous lives every year. Owing to the fact that non-coding RNAs (ncRNAs) such as long non-coding RNAs (lncRNAs) and microRNAs (miRNAs) interact with coding transcripts, and effectuate key roles in the tumorigenesis and metastasis of cervical cancer, there has been extensive research in recent years to explore their potential as biomarkers for early detection, or as therapeutic targets. Through this review, we aim to provide a comprehensive overview of the recent advancements in discoveries about cervical cancer-associated lncRNA-miRNA-mRNA axes, their dysregulation, and their roles in various signaling pathways associated with the growth, survival, invasion, and metastasis of cervical cancer cells.
View Article and Find Full Text PDFBackground: The role of fine needle aspiration cytology (FNAC) in the diagnosis of renal malignancies is established and has been getting more precise and important over a period of time. Knowledge of the pathology of uncommon renal neoplasms along with radiological and clinical correlations often aids in correct diagnosis.
Aims: The present study aims to describe the cytomorphological and immunohistochemical findings in the varied spectrum of renal tumors, other than renal cell carcinomas (RCC).
Lipases are one of the ubiquitous enzymes that belong to the hydrolases family and have a wide variety of applications. Cold-active lipases are of major attraction as they can act in lower temperatures and low water conditions because of their inherent greater flexibility. One of the novel applications of lipase is the enrichment of ω-3 polyunsaturated fatty acids (PUFA) in plant and fish oils.
View Article and Find Full Text PDF2,4-dimethyalmine is a herbicide commonly used by agriculturalist. Acute intoxication can cause fatal multiorgan damage. No antidote is available.
View Article and Find Full Text PDFIn the present study, bio-citric acid/tungsten oxide (WO) (BCAWO) nanoparticles (NPs) were prepared by using fruit extract as a reducing as well as a capping agent. The photocatalysts were characterized by UV-vis diffuse reflectance spectroscopy, powder X-ray diffraction (XRD), scanning electron microscopy (SEM), energy dispersive X-ray spectrometry (EDS), high-resolution transmission electron microscopy, and photoluminescence spectroscopy techniques. Diffraction peaks in the XRD spectrum were identified as the crystal planes of crystalline tungsten oxide.
View Article and Find Full Text PDFBackground: Anxiety disorders are commonly associated with a higher risk of fatal cardiovascular diseases (CVD). Anxiety disorders lead to dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis, thus weakening the key neuronal components of the autonomic nervous system (ANS) that are involved in cardiovascular functions, leading to increased cardiovascular risk.
Purpose: Impaired ANS activity, as reduced parasympathetic tone is strongly associated with an increased risk of CVD in anxiety disorders.
Secondary metabolites synthesized by endophytic fungi have garnered significant interest for their broad applications in treating various ailments. In this study involving 20 plant samples, 11 endophytic fungi were isolated and cultured, and Lasiodiplodia pseudotheobromae EF-9, derived from Hibiscus rosa-sinensis, demonstrated greater antibacterial efficacy than the other isolated endophytes. Phylogenetic analyses using 18S rRNA gene confirmed the EF-9 identity as L.
View Article and Find Full Text PDFTomato (Solanum lycopersicum) and chilli (Capsicum annuum) are globally significant vegetable crops susceptible to damping-off disease caused by Pythium aphanidermatum, leading to substantial yield losses. The study aimed to document the biocontrol and plant growth promotion potential of Streptomyces rochei against damping-off disease in tomato and chilli. The actinobacterial isolates ACS18 followed by ACT30, and AOE12 were accomplished as the most effective antagonists against P.
View Article and Find Full Text PDFThe present circumstances of Asian expatriates' wives residing in the United States and the effects of acculturation stress, parenthood stress, and depression on the distress disclosure intention have been examined this study. The nature of this investigation is exploratory. 611 married women with children who reside in the United States provided data, which was then processed with a measurement model, structural analysis, mediating analysis, moderating analysis, and regression analysis.
View Article and Find Full Text PDFMed Pharm Rep
October 2024
Background: Platelet concentrates are currently being researched for their potential to enhance bone formation.
Aim: The aim of this study is to quantitatively evaluate and compare bone regeneration in periapical lesions using a combination of platelet-rich plasma (PRP) + β-tricalcium phosphate (β-TCP) and platelet-rich fibrin (PRF) + β-TCP.
Methods: Ten subjects with periapical lesions measuring 10-20 mm in relation to maxillary incisors indicated for periapical surgery were selected.
A key contemporary challenge is enhancing the value of agro-industrial byproducts. Cellulose, the most abundant renewable resource, offers significant industrial potential due to its versatile properties. Produced in its pure form by various bacteria, cellulose is increasingly utilized in microscale and nanoscale fibers for composite reinforcement.
View Article and Find Full Text PDFEucalyptus oil consumption is well known to cause adverse effects on central nervous system like seizures, ataxia and unconsciousness. No antidote is available and treatment is largely supportive. We report a case of rhabdomyolysis with pigment cast nephropathy and acute kidney injury in a young female following eucalyptus oil consumption and its successful management.
View Article and Find Full Text PDFJ Pharm Bioallied Sci
July 2024
Background: Cardiovascular problems are the leading cause of death among adults in our country. These illnesses primarily affect metropolitan populations, particularly in major cities. To prevent these diseases, efforts have focused on identifying and controlling cardiovascular risk factors such sedentary lifestyle.
View Article and Find Full Text PDFPre-experimental one group pertest post-test research design was adopted to investigate the effectiveness of aqueous flower extract of Hibiscus sabdariffa in reduction of blood pressure, serum lipids among 60 prehypertensive patients. A self-structured questionnaire and manual sphygmomanometer and stethoscope monitored blood pressure levels before and after administering Hibiscus sabdariffa extract. Results showed a significant drop in blood pressure levels among prehypertensive patients with a mean difference score of 12.
View Article and Find Full Text PDFSocial media has become an integrated part of daily life, with an estimated 3 billion social media users worldwide. The purpose of current study was to investigate to assess the impact of social media platforms on mental wellbeing among college student at selected college. A descriptive research design was used a study the Impact of social media Plat forms on mental wellbeing among college students.
View Article and Find Full Text PDFBackground: Osteopenia refers to bone density that is not only normal but also not as low as that noted in osteoporosis. Osteopenia leads to osteoporosis and increases the risk of fractures. Current research is focused on agents that will prevent or slow the progression of bone loss.
View Article and Find Full Text PDFIntroduction: Rehabilitation after Total Knee Arthroplasty (TKA) often includes proprioceptive exercises to prevent falls, but studies on proprioceptive training have yielded conflicting findings. This study aims to explore impact of proprioceptive training on functional performance after TKA.
Methods: Eighty patients who underwent unilateral TKA were randomly assigned to a proprioceptive exercise (PE) group or a routine exercises (RE) group.
Primary dysmenorrhea denotes the onset of recurrent lower abdominal pain and uterine contractions throughout the bleeding phase of menstruation in the absence of any underlying pelvic pathology. Core stability exercise is considered a beneficial exercise program for managing several health problems. Various relaxation techniques can be used in womanhood with primary dysmenorrhea for relief of pain and improving their quality of life (QOL).
View Article and Find Full Text PDFComput Methods Biomech Biomed Engin
September 2024
Autism Spectrum Disorder (ASD) is a type of brain developmental disability that cannot be completely treated, but its impact can be reduced through early interventions. Early identification of neurological disorders will better assist in preserving the subjects' physical and mental health. Although numerous research works exist for detecting autism spectrum disorder, they are cumbersome and insufficient for dealing with real-time datasets.
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