Publications by authors named "Kartono"

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  • Non-melanoma skin cancers (NMSCs) are the most common type of cancer in the U.S., and image-guided superficial radiation therapy (IGSRT) effectively treats them, but the influence of patient comorbidities and socioeconomic status (SES) on treatment outcomes has been under-researched.
  • A large retrospective study analyzed nearly 20,000 NMSC lesions to determine how SES and comorbidity levels (using ADI and CCI metrics) affected recurrence rates after IGSRT, finding minimal differences in outcomes for both factors at 2, 4, and 6 years.
  • Results showed that neither SES nor comorbidity burden significantly impacted recurrence rates, suggesting that I
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  • The study compares the effectiveness of home-based vs. office-based phototherapy for psoriasis, highlighting that while office therapy is cost-effective, it’s often hard to access compared to the more patient-preferred home therapy, which lacks sufficient clinical data, especially for those with darker skin.
  • Conducted across 42 dermatology practices in the US, the trial involved 783 participants aged 12 and older with psoriasis, who were randomly assigned to either home or office phototherapy for 12 weeks, followed by another 12 weeks of observation.
  • Results showed that home phototherapy led to better skin clearance and quality of life improvements, with 32.8% of participants achieving clear skin compared to
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This study investigates the optimization of fabric dyeing using natural dyes extracted from Clitoria ternatea, Cudrania javanensis, and Hibiscus sabdarifa by enhancing the mordanting process with citric acid. The principle of adding citric acid is as a crosslinker agent between cotton fabric and dye through an esterification reaction. A central composite design (CCD) of the response surface methodology (RSM) is employed to optimize parameters.

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It can be difficult to delineate the cause of urticarial eruptions, and in chronic cases, it can be a challenging condition to effectively treat. Several forms of urticarial eruptions are well documented and established. Our review focuses on a form of urticaria that is less commonly reported: adrenergic urticaria.

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With the rise of Janus kinase (JAK) and Signal Transducer and Activator of Transcription (STAT) inhibitor use in dermatologic conditions, there has been increasing hope in treating extensive and difficult-to-treat inflammatory cutaneous conditions. Today we report a case of oral lichen planus successfully treated with an oral JAK1 inhibitor, upadacitinib. This case had been unresponsive by several standard methods but responded with 70% improvement within 1 month when treated with upadacitinib.

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  • Drug reactions are a significant concern in anti-cancer therapies, with less common risks like toxic erythema linked to chemotherapy.
  • Patients undergoing cancer treatments have weakened immune systems, making them more prone to infections.
  • The text discusses a rare case where a patient's skin condition evolved into a severe reaction after starting treatment with bevacizumab and lorlatinib, leading to a combined skin infection.
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  • Recombinant adeno-associated virus (rAAV) vectors are innovative tools for gene therapy aimed at treating neurodegenerative diseases, with the review providing an overview for newcomers to this rapidly evolving field.
  • The text covers significant milestones, current clinical trials focused on various gene strategies, and efforts to enhance the delivery efficiency of rAAV vectors specifically for brain applications.
  • Additionally, it addresses the components of rAAV vectors, highlights advancements that improve treatment effectiveness, and discusses potential risks like off-target effects and immune responses, along with approaches to mitigate these risks.
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  • - This report describes a unique case of argyria, a condition that causes skin discoloration, affecting only the nails due to the ingestion of colloidal silver.
  • - It emphasizes the importance of detecting argyria early, as initial signs can be subtle but crucial in preventing permanent skin changes.
  • - With the rising use of over-the-counter supplements, healthcare professionals should be aware of the early symptoms of argyria to provide timely intervention.
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Glioma is a human brain tumor that is very difficult to treat at an advanced stage. Studies of glioma biomarkers have shown that some markers are released into the bloodstream, so data from these markers indicate a decrease in the concentration of blood glucose and serum glucose in patients with glioma; these suggest an association between glucose and glioma. This decrease mechanism in glucose concentration can be described by the coupled ordinary differential equations of the early-stage glioma growth and interactions between glioma cells, immune cells, and glucose concentration.

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Covid-19 has severe implications for the emergence of negative stigmatization of specific individuals and community groups. Due to labeling and discrimination, mental attacks cause psychological distress so seriously that it requires proper handling. Therefore, this study aims to conduct a systematic literature review on articles on COVID-19 stigmatization.

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Bat communities can usually only be comprehensively monitored by combining ultrasound recording and trapping techniques. Here, we propose bat point counts, a novel, single method to sample all flying bats. We designed a sampling rig that combines a thermal scope to detect flying bats and their flight patterns, an ultrasound recorder to identify echolocating bat calls, and a near-infrared camera and LED illuminator to photograph bat morphology.

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Emerging technologies based on the detection of electro-magnetic energy offer promising opportunities for sampling biodiversity. We exploit their potential by showing here how they can be used in bat point counts-a novel method to sample flying bats-to overcome shortcomings of traditional sampling methods, and to maximize sampling coverage and taxonomic resolution of this elusive taxon with minimal sampling bias. We conducted bat point counts with a sampling rig combining a thermal scope to detect bats, an ultrasound recorder to obtain echolocation calls, and a near-infrared camera to capture bat morphology.

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A simple model for predicting Coronavirus Disease 2019 (COVID-19) epidemic is presented in this study. The prediction model is presented based on the classic Susceptible-Infectious-Recovered (SIR) model, which has been widely used to describe the epidemic time evolution of infectious diseases. The original version of the Kermack and McKendrick model is used in this study.

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The COVID-19 pandemic was impacting the health and economy around the world. All countries have taken measures to control the spread of the epidemic. Because it is not known when the epidemic will end in several countries, then the prediction of the COVID-19 pandemic is a very important challenge.

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Background: Automated sound recorders are a popular sampling tool in ecology. However, the microphones themselves received little attention so far, and specifications that determine the recordings' sound quality are seldom mentioned. Here, we demonstrate the importance of microphone signal-to-noise ratio for sampling sonant animals.

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This study, we analyzed the effect of boosting tumor infiltrating lymphocyte in immunotherapy using mathematical modeling. In this model, tumor growth is described as a tumor cells population with immunotherapy. This model also describes the effect of Tumor Infiltrating Lymphocytes (TIL), interleukin-2 (IL-2) and interferon alpha (INF-alpha) on dynamics of tumor cells.

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The Bergman's minimal model of glucose and insulin plasma levels is commonly used to analyse the results of glucose tolerance tests in humans. In this paper, we present the modified minimal model with plasma insulin compartment under the assumption that if the plasma glucose compartment drops below the basal glucose levels, the rate of insulin entering the plasma glucose compartment is zero. Insulin is cleared from the plasma insulin compartment at a rate proportional to the amount of insulin in the plasma insulin compartment.

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Context: The median urinary iodine concentration (UIC) is a biomarker of iodine intake. According to the World Health Organization, a median UIC in the range 100-199 μg/L indicates adequate and 200-299 μg/L more than adequate intake. Thyroglobulin (Tg) may be a promising functional biomarker of both iodine deficiency and excess.

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Objective: To evaluate population-based cardiovascular risk scores and coronary artery calcification scores (CACS) in amputees.

Design: A retrospective cohort study of 1300 veterans in a cardiac computed tomography database.

Setting: 1B Veterans Administration medical center.

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Nephrogenic systemic fibrosis (NSF) is a progressive and potentially fatal fibrosing skin disorder found mainly in patients with renal insufficiency. NSF is characterized by thickened and hyperpigmented skin lesions with or without systemic involvement. In essentially all patients, this disease entity has been associated with the administration of gadolinium contrast agents for imaging purposes.

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Widely considered the gold standard treatment option for tattoo removal, the use of Q-switched lasers may very rarely result in the formation of large bulla. While very disconcerting to patients, these lesions are easily managed and, with proper care, heal quickly with no long-term consequences. The authors present three cases of patients who had bullous reactions shortly after receiving Q-switched laser treatment of tattoo ink.

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