Publications by authors named "Kai-Fu Yang"

Actomyosin networks constrict cell area and junctions to alter cell and tissue shape. However, during cell expansion under mechanical stress, actomyosin networks are strengthened and polarized to relax stress. Thus, cells face a conflicting situation between the enhanced actomyosin contractile properties and the expansion behaviour of the cell or tissue.

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Color constancy is a basic step for achieving stable color perception in both biological visual systems and the image signal processing (ISP) pipeline of cameras. So far, there have been numerous computational models of color constancy that focus on scenes under normal light conditions but are less concerned with nighttime scenes. Compared with daytime scenes, nighttime scenes usually suffer from relatively higher-level noise and insufficient lighting, which usually degrade the performance of color constancy methods designed for scenes under normal light.

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The geometry of retinal layers is an important imaging feature for the diagnosis of some ophthalmic diseases. In recent years, retinal layer segmentation methods for optical coherence tomography (OCT) images have emerged one after another, and huge progress has been achieved. However, challenges due to interference factors such as noise, blurring, fundus effusion, and tissue artifacts remain in existing methods, primarily manifesting as intra-layer false positives and inter-layer boundary deviation.

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The geometric morphology of retinal vessels reflects the state of cardiovascular health, and fundus images are important reference materials for ophthalmologists. Great progress has been made in automated vessel segmentation, but few studies have focused on thin vessel breakage and false-positives in areas with lesions or low contrast. In this work, we propose a new network, differential matched filtering guided attention UNet (DMF-AU), to address these issues, incorporating a differential matched filtering layer, feature anisotropic attention, and a multiscale consistency constrained backbone to perform thin vessel segmentation.

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The morphology of retinal vessels is closely associated with many kinds of ophthalmic diseases. Although huge progress in retinal vessel segmentation has been achieved with the advancement of deep learning, some challenging issues remain. For example, vessels can be disturbed or covered by other components presented in the retina (such as optic disc or lesions).

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Article Synopsis
  • Thyroid nodules are common lesions, and the incidence of thyroid cancer has sharply risen over the past 30 years, making accurate diagnosis crucial.
  • The study introduces LoGo-Net, an advanced model that mimics human vision to classify benign and malignant nodules using a novel feature extraction method that separates local and global features.
  • Extensive testing on a large dataset demonstrated that LoGo-Net achieves a high accuracy of 89.33%, making it a promising tool for clinical use, especially in under-resourced settings for early cancer detection.
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Before being captured by observers, the information carried by light may be attenuated by the transmission medium. According to the atmospheric scattering model, this attenuation is wavelength-dependent and increases with distance. However, most existing haze removal methods ignore this wavelength dependency and therefore cannot handle well the color distortions caused by it.

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Article Synopsis
  • The human visual system can group visual stimuli into organized units, which this article explores through a computational model inspired by tolerance space theory.
  • The model simulates how people perceive dot patterns, utilizing one- and two-reach methods to analyze and reconstruct these patterns in an extended tolerance space (ETS).
  • The results show that the model closely matches human perception, effectively demonstrating Gestalt principles and offering potential uses in computer vision, while also revealing its connection to the Pure Distance Law.
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Retinal fundus photography has been widely used to diagnose various prevalent diseases because many important diseases manifest themselves on the retina. However, the quality of fundus images obtained from practical clinical environments is not always good enough for diagnosis due to uneven illumination, blurring, low contrast, etc. In this paper, we propose a simple yet efficient method for fundus image enhancement.

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The limited dynamic range of regular screens restricts the display of high dynamic range (HDR) images. Inspired by retinal processing mechanisms, we propose a tone mapping method to address this problem. In the retina, horizontal cells (HCs) adaptively adjust their receptive field (RF) size based on the local stimuli to regulate the visual signals absorbed by photoreceptors.

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Image enhancement is an important pre-processing step for many computer vision applications especially regarding the scenes in poor visibility conditions. In this work, we develop a unified two-pathway model inspired by the biological vision, especially the early visual mechanisms, which contributes to image enhancement tasks including low dynamic range (LDR) image enhancement and high dynamic range (HDR) image tone mapping. Firstly, the input image is separated and sent into two visual pathways: structure-pathway and detail-pathway, corresponding to the M-and P-pathway in the early visual system, which code the low-and high-frequency visual information, respectively.

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Purpose: To demonstrate a feasible procedure of robot-assisted extraperitoneal radical prostatectomy single site plus two model to overcome the limitation of traditional single-port laparoscopic surgery.

Materials And Methods: All consecutive cases of robot-assisted extraperitoneal radical prostatectomy single site plus two model between November 2015 and April 2016 in our institution were included. We analyze the surgical and continence outcome.

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This study investigated the character decomposition and transposition processes of Chinese two-character compound words (canonical and transposed words) and pseudowords in the right and left visual fields using a dual-target rapid serial visual presentation paradigm. The results confirmed a right visual field superiority for canonical words, but this advantage vanished for transposed words. The findings further indicated that the same quality of lexical processing could be obtained from the foveal and parafoveal regions of the right and left visual fields, regardless of the character order, but not in the periphery of the right visual field.

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We define the task of salient structure (SS) detection to unify the saliency-related tasks, such as fixation prediction, salient object detection, and detection of other structures of interest in cluttered environments. To solve such SS detection tasks, a unified framework inspired by the two-pathway-based search strategy of biological vision is proposed in this paper. First, a contour-based spatial prior (CBSP) is extracted based on the layout of edges in the given scene along a fast non-selective pathway, which provides a rough, task-irrelevant, and robust estimation of the locations where the potential SSs are present.

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The double-opponent (DO) color-sensitive cells in the primary visual cortex (V1) of the human visual system (HVS) have long been recognized as the physiological basis of color constancy. In this work we propose a new color constancy model by imitating the functional properties of the HVS from the single-opponent (SO) cells in the retina to the DO cells in V1 and the possible neurons in the higher visual cortexes. The idea behind the proposed double-opponency based color constancy (DOCC) model originates from the substantial observation that the color distribution of the responses of DO cells to the color-biased images coincides well with the vector denoting the light source color.

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Article Synopsis
  • Researchers studied the role of two types of inhibition in neurons of the primary visual cortex (V1) in primates and cats, focusing on how they affect contour detection.
  • They created models to analyze the performance of V1 neurons using both orientation-selective and non-selective surround inhibition, finding that these combined approaches were more effective than using either type alone.
  • The results suggest that V1 neurons collaborate adaptively to process complex visual information, which could inform the development of better machine-vision technology.
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Brightness and color are two basic visual features integrated by the human visual system (HVS) to gain a better understanding of color natural scenes. Aiming to combine these two cues to maximize the reliability of boundary detection in natural scenes, we propose a new framework based on the color-opponent mechanisms of a certain type of color-sensitive double-opponent (DO) cells in the primary visual cortex (V1) of HVS. This type of DO cells has oriented receptive field with both chromatically and spatially opponent structure.

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Background: Urothelial carcinoma (UC) originating from the bladder (UBUC) and upper urinary tract (UTUC) is the most common type of urinary tract tumor. While its pathogenesis remains obscured. Computerizing a published transcriptomic database of UBUC (GSE31684), we identified Inhibin, Beta A (INHBA) as the most significant upregulated gene associated with tumor progression among those associated with growth factor activity (GO:0008083).

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To effectively perform visual tasks like detecting contours, the visual system normally needs to integrate multiple visual features. Sufficient physiological studies have revealed that for a large number of neurons in the primary visual cortex (V1) of monkeys and cats, neuronal responses elicited by the stimuli placed within the classical receptive field (CRF) are substantially modulated, normally inhibited, when difference exists between the CRF and its surround, namely, non-CRF, for various local features. The exquisite sensitivity of V1 neurons to the center-surround stimulus configuration is thought to serve important perceptual functions, including contour detection.

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Prostate cancer (PCa) is the most common type of cancer in males in the USA and the incidence is increasing. For castration-resistant PCa (CRPC), previous studies have identified docetaxel-based chemotherapy as the first-line therapy. In the present study, the efficacy of docetaxel-based chemotherapy was investigated in a population of patients with CRPC.

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