Synergistic activation of peroxydisulfate by photothermal and FeS-loaded air-laid cloth in a shallow continuous flow reactor.

Synergistic activation of persulfate by photothermal and solid catalysts is an effective method for degrading organic pollutants. However, the batch reaction mode not only fails to fully utilize photothermal, but also makes it hard to separate the solid catalysts from the reaction solution. In this work, a shallow continuous flow way of effluent was set up for synergistic activation of peroxydisulfate (PDS) by photothermal and FeS-loaded air-laid cloth (FeS-ALC).

Synchronous transperitoneal robotic-assisted bilateral cortical-sparing adrenalectomy for pheochromocytomas in a patient with multiple endocrine neoplasia type 2a (MEN2A) syndrome: a case report.

Background: Pheochromocytoma is a rare neuroendocrine tumor, and bilateral pheochromocytomas is even less common. Due to the limited experience with such cases, this study aims to explore the optimal surgical strategy, assess the potential advantages of robotic surgery, and evaluate surgical outcomes for managing bilateral pheochromocytomas.

Case Description: This report presented a case of a 33-year-old woman with bilateral pheochromocytomas related to multiple endocrine neoplasia type 2a (MEN2A), who was successfully managed by synchronous transperitoneal robotic-assisted bilateral cortical-sparing adrenalectomy.

Impact of Mg Substitution on the Structure, Stability, and Properties of the NaFeF Weberite Cathode.

Of the few weberite-type Na-ion cathodes explored to date, NaFeF exhibits the best performance, with capacities up to 184 mAh/g and energy densities up to 550 Wh/kg reported for this material. However, the development of robust structure-property relationships for this material is complicated by its tendency to form as a mixture of metastable polymorphs, and transform to a lower-energy Na FeF perovskite compound during electrochemical cycling. Our first-principles-guided exploration of Fe-based weberite solid solutions with redox-inactive Mg and Al predicts an enhanced thermodynamic stability of NaMg Fe F as the Mg content is increased, and the = 0.

17β-estradiol promotes osteogenic differentiation of BMSCs by regulating mitophagy through ARC.

The study aims to elucidate the mechanism through which 17β-estradiol facilitates osteogenic differentiation in bone marrow mesenchymal stem cells (BMSCs). In our study, lentiviral transfection was employed to establish apoptosis repressor with caspase recruitment domain (ARC) knockdown or overexpression in BMSCs. The impact of 17β-estradiol on ARC expression was assessed using western blot, RT-PCR and immunofluorescence.

The glycerol stabilized calcium phosphate cluster for rapid remineralization of tooth enamel by a water-triggered transformation.

Remineralization is a common strategy for the repair of early demineralized tooth enamels, but the harsh dynamic oral environment often hampers its efficacy. Rapid remineralization is expected to address this challenge, however, the stabilizers of remineralization materials often resist their transformation required for repair. Here, by dissolving the ions of calcium and phosphate in glycerol-dominant solvents, we obtain the calcium phosphate clusters (1-2 nm), which are stabilized by glycerol (with high viscosity and affinity to clusters), but can perform a fast enamel repair via the water-triggered transformation in both static and dynamic environments.

Multi-omics reveals the mechanism of Sparassis latifolia polysaccharides to relieve cyclophosphamide-induced immune injury in liver of mice.

The present study aimed to investigate the impact of Sparassis latifolia polysaccharides (SLPs) on hepatic immune function in cyclophosphamide (CTX)-induced immunocompromised mice. Our findings demonstrated that SLPs effectively suppressed the production of alanine aminotransferase (ALT), aspartate aminotransferase (AST), inflammatory factors, and acute phase proteins, while improving the hepatic oxidative stress state. Additionally, SLPs exerted inhibitory effects on inflammatory cell infiltration within hepatic tissue.

Driver mutation landscape of acute myeloid leukemia provides insights for neoantigen-based immunotherapy.

Acute myeloid leukemia (AML) has lagged in benefiting from immunotherapies, primarily due to the scarcity of actionable AML-specific antigens. Driver mutations represent promising immunogenic targets, but a comprehensive characterization of the AML neoantigen landscape and their impact on patient outcomes and the AML immune microenvironment remain unclear. Herein, we conducted matched DNA and RNA sequencing on 304 AML patients and extensively integrated data from additional ∼2500 AML cases, identifying 49 driver genes, notably characterized by a significant proportion of insertions and deletions (indels).

AI-driven system for non-contact continuous nocturnal blood pressure monitoring using fiber optic ballistocardiography.

Continuous monitoring of nocturnal blood pressure is crucial for hypertension management and cardiovascular risk assessment. However, current clinical methods are invasive and discomforting, posing challenges. These traditional techniques often disrupt sleep, impacting patient compliance and measurement accuracy.

Examining the relationship between CDAI and frailty and its manifestation in Parkinson's disease: a cross-sectional study.

Background: Higher intake of antioxidants is associated with reduced risk of various chronic diseases. However, the relationship between composite dietary antioxidants and frailty has not been characterized, especially in neurodegenerative conditions like Parkinson's disease (PD) where frailty is highly prevalent. This study aimed to investigate the association between composite dietary antioxidant index (CDAI), a composite score reflecting antioxidant vitamin and mineral intakes, and frailty risk in the general United States (US) population and PD patients.

Above-Room-Temperature Ferromagnetism Regulation in Two-Dimensional Heterostructures by van der Waals Interfacial Magnetochemistry.

Most methods for regulating physical and chemical properties of materials involve the breaking and formation of chemical bonds, which inevitably change local structures. Two-dimensional (2D) ferromagnets are critical for spintronic memory and quantum devices, but most of them maintain ferromagnetism at low temperature, and multiaspect control of 2D ferromagnetism at room temperature or above is still missing. Here, we report a nondestructive, van der Waals (vdW) interfacial magnetochemistry strategy for above-room-temperature, multiaspect 2D ferromagnetism regulation.

Reassessing the Role of Thermal Convection in Simultaneous Water Production and Pollutant Degradation in Interfacial Photothermal-Photocatalytic Systems.

The interfacial photothermal-photocatalytic systems can generate clean water while purifying wastewater containing organic pollutants, but the impact of thermal convection on synergistic effects remains unexplored. This paper aims to regulate the thermal convection at the interface to significantly enhance the synergistic effect of interfacial photothermal-photocatalytic systems. A novel heterogeneous structure comprising iron-based metal-organic frameworks and multi-walled carbon nanotubes with a gelatin-polyvinyl alcohol (PVA) double network hydrogel (MWCNTs@NM88B/PVA/gelatin hydrogel, denoted as MMH) is developed and employed in the construction of the solar-driven interfacial evaporation (SIE) system.

Exploring the effect of pH-shifting on the gel properties and interaction of heat-induced Flammulina velutipes polysaccharide-porcine myofibrillar protein for improving the quality of Flammulina velutipes-pork patties.

This study primarily investigated the impact of pH-shifting on the gel properties of Flammulina velutipes polysaccharide (FVP)-porcine myofibrillar protein (MPs) gels, aiming to improve the quality of Flammulina velutipes-pork patties. Our findings revealed that the water holding capacity (81.72 %), oil holding capacity (87.

overexpression stimulates cell proliferation and is predictive of poor outcome in ovarian cancer.

Background: Members of the S100 gene family are frequently dysregulated in various cancers, including ovarian cancer (OC). Despite this, the prognostic implications of individual S100 genes in OC remain poorly understood. This study aimed to explore the prognostic significance of expression in OC and assess its potential as a therapeutic target.

CSTF2 Supports Hypoxia Tolerance in Hepatocellular Carcinoma by Enabling m6A Modification Evasion of PGK1 to Enhance Glycolysis.

Cleavage stimulation factor subunit 2 (CSTF2) is a fundamental factor in the regulation of 3'-end cleavage and alternative polyadenylation of pre-mRNAs. Previous work has identified a tumor-promoting role of CSTF2, suggesting that it may represent a potential therapeutic target. Here, we aimed to elucidate the mechanistic function of CSTF2 in hepatocellular carcinoma (HCC).

Synergistic co-evolution of rhizosphere bacteria in response to acidification amelioration strategies: impacts on the alleviation of tobacco wilt and underlying mechanisms.

Soil acidification represents a severe threat to tobacco cultivation regions in South China, exacerbating bacterial wilt caused by . The comprehension of the underlying mechanisms that facilitate the restoration of rhizosphere microbial communities in "healthy soils" is imperative for ecologically managing tobacco bacterial wilt. This study focuses on acidified tobacco soils that have been subjected to continuous cultivation for 20 years.

Ultrafast dynamics in spatially confined photoisomerization: accelerated simulations through machine learning models.

This study sheds light on the exploration of photoresponsive host-guest systems, highlighting the intricate interplay between confined spaces and photosensitive guest molecules. Conducting nonadiabatic molecular dynamics (NAMD) simulations based on electronic structure calculations for such large systems remains a formidable challenge. By leveraging machine learning (ML) as an accelerator for NAMD simulations, we analytically constructed excited-state potential energy surfaces along relevant collective variables to investigate photoisomerization processes efficiently.

Metabolomics and 16S rDNA sequencing of intestinal flora reveal the regulation of Sparassis latifolia polysaccharides on splenic immune function in lead-exposed mice.

Sparassis latifolia polysaccharides (SLPs) have immunomodulatory activity and lead excretion ability, but its regulatory mechanism through the gut microbiota-spleen axis has not been elucidated. In this study, spleen metabolomics and intestinal flora sequencing were combined to explore the regulatory mechanism of SLPs on spleen immune function in lead-exposed mice. The results showed that SLPs effectively reduced spleen lead content, alleviated spleen enlargement and oxidative stress.

Stable Strained Donor-Free Silanone and Its Derived NHC-Stabilized Disilacyclobutadiene and Cyclic Alkenyl Silylene.

The strained silanone was obtained by the reaction of disilacyclobutene with NO. Silanone exhibited unprecedented thermal stability in both the solid state and solution. DFT calculations on revealed that the highly polarized Si═O double bond is effectively stabilized by its electron delocalization with the unsaturated SiC ring.

A Masked Boryl-Substituted Oxo-Bridged Bis-Silylene: Synthesis and Reductive-Elimination and Synergistic Oxidative-Addition Reactivity.

Controlled oxidation of NHB-stabilized disilyne (NHB)Si ≡ Si(NHB) (, NHB = [ArN(CMe)NAr]B, Ar = 2,6-PrCH) with one equivalent of trimethylamine N-oxide (MeN─O) in dry -hexane gave oxo-bridged bis-silepin in high yields. DFT calculations disclosed that silepin is only more stable by 13.4 kcal/mol than the corresponding oxo-bridged bis-silylene intermediate (NHB)Si(μ-O)Si(NHB), and was very likely to be formed by the insertion of the two divalent Si atoms into the pendant aryl rings in bis-silylene intermediate .