Serum CIAPIN1 is lower in septic patients with cardiac dysfunction.

The study aimed to investigate the clinical significance of serum cytokine-induced apoptosis inhibitor 1 (CIAPIN1) and its potential impact on cardiac dysfunction and inflammatory response induced by sepsis. A cross-sectional study was conducted in an intensive care unit (ICU) involving 80 healthy individuals and 95 severe sepsis patients. The data were analyzed to establish the correlation between CIAPIN1 levels and the onset of cardiac dysfunction in patients with sepsis.

GFI-Net: Global Feature Interaction Network for Monocular Depth Estimation.

Monocular depth estimation techniques are used to recover the distance from the target to the camera plane in an image scene. However, there are still several problems, such as insufficient estimation accuracy, the inaccurate localization of details, and depth discontinuity in planes parallel to the camera plane. To solve these problems, we propose the Global Feature Interaction Network (GFI-Net), which aims to utilize geometric features, such as object locations and vanishing points, on a global scale.

The molecular mechanism of cardiac injury in SARS-CoV-2 infection: Focus on mitochondrial dysfunction.

Background: Coronavirus disease 2019(COVID-19) caused a large number of infections worldwide. Although some patients recovered from the disease, some of the other problems that accompanied it, such as cardiac injury, could affect the patient's subsequent quality of life and prognosis.

Objectives: To clarify the molecular mechanism of cardiac injury in SARS-CoV-2 Infection.

Increased Serum Trimethylamine N-Oxide Level in Type 2 Diabetic Patients with Mild Cognitive Impairment.

Purpose: Trimethylamine N-oxide (TMAO) is a metabolite of phosphatidylcholine in red meat and other diets, which is associated with cardiovascular and other diseases. The aim of this study is to evaluate the associations of serum TMAO with mild cognitive impairment (MCI) in the Chinese type 2 diabetes mellitus (T2DM) population.

Materials And Methods: A total of 253 hospitalized T2DM patients and 150 healthy controls were included in this cross-sectional study.

3D Object Recognition in Cluttered Scenes with Local Surface Features: A Survey.

3D object recognition in cluttered scenes is a rapidly growing research area. Based on the used types of features, 3D object recognition methods can broadly be divided into two categories-global or local feature based methods. Intensive research has been done on local surface feature based methods as they are more robust to occlusion and clutter which are frequently present in a real-world scene.

[Classification technique for hyperspectral image based on subspace of bands feature extraction and LS-SVM].

The present paper proposes a novel hyperspectral image classification algorithm based on LS-SVM (least squares support vector machine). The LS-SVM uses the features extracted from subspace of bands (SOB). The maximum noise fraction (MNF) method is adopted as the feature extraction method.

[Pulmonary adenocarcinoma with micropapillary pattern: a clinicopathologic and immunohistochemical study].

Objective: To study the clinicopathologic characteristics and immunohistochemical profile of lung adenocarcinomas with a micropapillary pattern (MPP).

Methods: Among 135 cases of lung adenocarcinomas, the clinical, histological and immunohistochemical features of 48 cases of lung adenocarcinomas with a micropapillary components (the micropapillary components > or = 10%) were studied. The literature was reviewed.

[Intraductal papillary mucinous neoplasm of pancreas: a clinicopathologic and immunohistochemical study of 19 cases].

Objective: To study the clinicopathologic features and diagnosis of intraductal papillary mucinous neoplasm (IPMN) of the pancreas.

Methods: Nineteen cases of IPMN encountered during the period from 1999 to 2007 were studied by light microscopy and immunohistochemistry.

Results: IPMN occurred more often in males (68%).

[Clinicopathologic study of primary marginal zone B-cell lymphoma of MALT type and lymphoid hyperplasia of lung].

Objective: To study the clinicopathologic features, immunohistochemical findings and immunoglobulin heavy chain (IgH) gene rearrangement results of primary pulmonary mucosa-associated lymphoid tissue lymphoma (MALToma) and reactive lymphoid hyperplasia.

Methods: Twenty cases, included 13 cases of pulmonary MALToma and 7 cases of pulmonary lymphoid hyperplasia, encountered during the period from 1989 to 2007, were retrospectively analyzed. The samples were paraffin-embedded and stained with hematoxylin and eosin.

[Role of HPV DNA detection and p16(INK4A) protein expression in diagnosis of endocervical adenocarcinoma].

Objectives: To evaluate the significance of p16(INK4A) protein expression and positivity for HPV DNA in distinguishing between endocervical and endometrial adenocarcinoma.

Methods: Expression of p16(INK4A) protein in 30 cases of endocervical adenocarcinoma and 10 cases of endometrial adenocarcinoma was assessed by immunohistochemistry. In-situ hybridization for human papillomavirus (HPV) DNA was also performed in 20 cases of endocervical adenocarcinoma and 10 cases of endometrial adenocarcinoma.

[Atypical adenomatous hyperplasia of lung: clinicopathologic study of 8 cases and review of literature].

Objective: To study the clinicopathologic and immunohistochemical features of atypical adenomatous hyperplasia (AAH) of lung.

Methods: Eight cases of AAH of lung were studied by light microscopy and immunohistochemical staining for p16, thyroid transcription factor-1 (TTF-1), Ki-67, p53, epidermal growth factor receptor (EGFR) and c-erbB-2.

Results: The mean age of the patients was 52 years.

[Distinction between benign and malignant pheochromocytomas].

Objectives: To investigate the differences in morphology, immunohistochemistry, DNA ploidy status, LOH and MSI of 11q13 and 1p between benign and malignant pheochromocytomas, and to find the marker or markers useful in distinction between benign and malignant pheochromocytoma or for predicting the malignant potential of this tumor.

Methods: Twenty-two cases of clinically documented benign and malignant pheochromocytomas from the files of Peking Union Medical College Hospital were analyzed. Aside from histological study, Ki-67, p53, CgA, S-100, PCNA and survivin immunohistochemistry studies were performed.

[Morphological study of severe acute respiratory syndrome (SARS)].

Objective: Seven cases of autopsy from SARS patients are studied to investigate the pathogenesis and the pathologic changes of the major organs.

Methods: Detailed gross and microscopic examination of the autopsy specimen is performed, including lung, heart, liver, kidney, spleen and lymph nodes.

Results: All of the lungs are markedly enlarged and consolidated.

[Immunohistochemical investigation of lungs with severe acute respiratory syndrome].

Objective: To investigate the roles of different cells in the pulmonary lesions in the severe acute respiratory syndrome (SARS) patients.

Methods: The monoclonal antibodies of CD8, CD20, CD34, LCA, CD56, CD68, and AE1/AE3 are used to demonstrate the different cells in the lung specimens of SARS patients in order to study the patterns of cell responses in this new disease. Meanwhile the HE stained slides were also carefully studied to compare with the results of immunohistochemical staining.

[Lung pathology of severe acute respiratory syndrome].

Objective: To study the morphological features of the lungs obtained from autopsies of severe acute respiratory syndrome (SARS) patients.

Methods: Bilateral lungs from 7 patients died from SARS were carefully studied grossly and microscopically. All tissues from these cases were routinely processed and carefully studied.