The dynamics of circulating SARS-CoV-2 lineages in Bogor and surrounding areas reflect variant shifting during the first and second waves of COVID-19 in Indonesia.

Background: Indonesia is one of the Southeast Asian countries with high case numbers of COVID-19 with up to 4.2 million confirmed cases by 29 October 2021. Understanding the genome of SARS-CoV-2 is crucial for delivering public health intervention as certain variants may have different attributes that can potentially affect their transmissibility, as well as the performance of diagnostics, vaccines, and therapeutics.

Genetic characterization and phylogenetic study of Lakor goat from Southwest Maluku Regency based on mitochondrial COI gene.

Aim: This study is aimed at characterizing the genetic and phylogenetic structure of Lakor goats as indigenous livestock from the Southwest Maluku Regency based on mitochondrial COI gene sequences.

Materials And Methods: The genomes of 103 follicle samples from Lakor goats, collected from Lakor Island, were analyzed. The polymerase chain reaction was used to amplify 1548 bp of the mitochondrial COI gene using two primer pairs (COIA and COIB).

Optimization of expression JTAT protein with emphasis on transformation efficiency and IPTG concentration.

One of small accessory genes between and is gene encoding TAT protein. This research was aimed to optimize the expression of Jembrana TAT (JTAT) protein with preparing () in advance using adopted methods of M1 (MgCl + CaCl) and M2 (CaCl + Glycerol). The best transformation efficiency resulting from a better transformation method was used to subsequent expression of JTAT protein.

Prenatal hypoxia-ischemia decreases spatial memory and increases aggression during adolescence.

Prenatal hypoxia-ischemia (HI) is a major cause of mortality and chronic neurological diseases in newborns. HI contributes to the emergence of several neurological disorders such as cognitive and behavioral deficits due to the atypical brain development. This study aimed at assessing the effects of prenatal HI on the spatial memory and aggression of rats during adolescence.