Publications by authors named "Hujiya"
Article Synopsis
- The study investigated the cardioprotective effects of Sanwei sandalwood decoction against Adriamycin-induced Chronic Heart Failure using network pharmacology and molecular docking methods.
- Results showed that the decoction improved heart function in rats, indicated by enhanced ejection fraction and reduced serum markers related to heart damage.
- It also found that treatment lowered the expression of aquaporins (Aquaporin-1, 4, and 7), suggesting their significant role in heart cell health and response to oxidative stress during chronic heart failure.
In mammalian cells, four types of sialidase have been described and found to behave in different ways during carcinogenesis. We previously demonstrated that a human sialidase associated with plasma membranes (NEU3) is up-regulated in human colon cancer and is involved in suppression of apoptosis. Here we document altered expression of another human sialidase, the recently identified NEU4, and evidence of its influence on the malignant phenotype in colon cancers.
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