Publications by authors named "Hong Jin Jeon"
Objective: Previous studies have investigated obesity and appetite changes in patients with depression, which consisted of a small age range of adults and used body mass index rather than abdominal obesity. The objective of this study is to examine the relationship between abdominal obesity and the risk of depression by sex and age groups.
Methods: This study utilized the National Health Insurance Sharing Service (NHISS) database of South Korea, which includes those over 20 years old and who had undergone a health examination in 2009 and their claims data between 2009 and 2018.
Background: It is unclear if certain post-stroke somatic symptoms load onto items of the Patient Health Questionnaire-9 (PHQ-9), a self-report depression questionnaire. We investigated these concerns in a stroke sample using factor analysis, benchmarked against a non-stroke comparison group.
Methods: The secondary dataset constituted 787 stroke and 12,016 non-stroke participants.
Article Synopsis
- The study investigates how using small datasets to select an optimal cutoff score for the Patient Health Questionnaire-9 (PHQ-9) can lead to inaccurate results.
- Researchers evaluated whether data-driven methods for cutoff selection resulted in scores that were significantly different from the true population optimal score and if these methods produced biased accuracy estimates.
- Findings showed that many small studies frequently failed to identify the correct optimal cutoff score, particularly in smaller samples, leading to an overestimation of test sensitivity.
Article Synopsis
- - This study investigated the link between late-onset depression (LOD) and amyloid deposition in the brain, comparing 40 LOD patients (diagnosed after age 60) with 21 healthy controls (HC) using PET imaging and neuropsychological tests.
- - Results showed no significant differences in amyloid-beta (Aβ) levels between LOD patients and HC, and Aβ levels did not correlate with the severity of depressive symptoms; however, higher somatic anxiety was linked to lower Aβ levels in certain brain areas.
- - While cognitive improvements were observed in LOD patients after three months of antidepressant treatment, these improvements did not correlate with changes in amyloid deposition, suggesting different underlying mechanisms for cognitive recovery and amy
With an increasing societal need for digital therapy solutions for poor mental health, we face a corresponding rise in demand for scientifically validated digital contents. In this study we aimed to lay a sound scientific foundation for the development of brain-based digital therapeutics to assess and monitor cognitive effects of social and emotional bias across diverse populations and age-ranges. First, we developed three computerized cognitive tasks using animated graphics: 1) an emotional flanker task designed to test attentional bias, 2) an emotional go-no-go task to measure bias in memory and executive function, and 3) an emotional social evaluation task to measure sensitivity to social judgments.
View Article and Find Full Text PDFBackground: The use of virtual reality (VR)-based biofeedback (BF), a relatively new intervention, is a non-pharmacological treatment of depressive and anxiety symptoms. However, studies on VR-based BF are lacking and inconclusive.
Methods: A total of 131 adults were recruited from the community.
Article Synopsis
- The study explored the link between narrowing of cerebral arteries (stenosis) and depressive symptoms in elderly patients over 65 years old, using data from a psychiatric clinic over nearly two decades.
- Among 365 participants, 29.6% had cerebral artery stenosis, and those with stenosis had higher depression scores on the Geriatric Depression Scale (GDS-15).
- Specifically, bilateral middle cerebral artery (MCA) stenosis and left posterior cerebral artery (PCA) stenosis were significantly associated with greater depressive symptoms, with bilateral MCA stenosis indicating a stronger correlation with depression severity.
Background: We investigated the risks of depression/anxiety in patients with multiple sclerosis (pwMS) or patients with neuromyelitis optica spectrum disorder (pwNMOSD).
Objectives: MS/NMOSD cohorts were collected from Korean National Health Insurance Service, using the International Classification of Diseases-10th and information on Rare Intractable Disease program. Patients who were younger than 20 years, had a previous depression/anxiety, or died in the index year were excluded.
Background: Anhedonia, a core diagnostic feature for major depressive disorder (MDD), is defined as the loss of pleasure and interest in daily activities. Its prevalence in MDD patients vary from 35 to 70%. Anhedonia in MDD negatively impacts functioning and is associated with treatment resistance and poorer prognosis for various clinical outcomes.
View Article and Find Full Text PDFArticle Synopsis
- The study aimed to explore the link between depression, antidepressant use, and the risk of atherosclerotic cardiovascular disease (ASCVD) using South Korean national claims data.
- The results showed that individuals with depression who were taking antidepressants had a higher risk of developing ASCVD, whereas those without antidepressant treatment had a lower risk compared to healthy controls.
- Specifically, tricyclic antidepressants were associated with the highest ASCVD risk among users, and the increased risk was noted in both antidepressant groups, particularly impacting young adults.
Introduction: The aim of this study was to determine associations between changes of metabolic parameters and the development of BD using nationally representative data.
Methods: We used health examination data provided by the South Korean National Health Insurance System (NHIS) ( = 8,326,953). The variability of each metabolic parameter including weight circumference, blood pressure, fasting blood glucose, high-density lipoprotein cholesterol, and triglyceride levels was caculated using variability independent of mean (VIM) indices.
The association of bipolar disorder (BD) with the risk of cardiometabolic diseases and premature death in Asians needs to be further determined. Relatively less attention has been paid to heart failure (HF) among cardiometabolic outcomes. We analyzed the Korean National Health Insurance Service database (2002-2018) for this population-based, matched cohort study.
View Article and Find Full Text PDFBackground: Depression is a risk factor for dementia and weight change can appear as a symptom of depression. However, the association between weight change after the diagnosis of depression and the risk of dementia is poorly established. This study aimed to investigate the association between weight change before and after a diagnosis of depression with the subsequent risk of dementia.
View Article and Find Full Text PDFBackgruound: The effects of psychotic disorders on cardiometabolic diseases and premature death need to be determined in Asian populations.
Methods: In this population-based matched cohort study, the Korean National Health Insurance Service database (2002 to 2018) was used. The risk of type 2 diabetes mellitus (T2DM), acute myocardial infarction (AMI), ischemic stroke, composite of all cardiometabolic diseases, and all-cause death during follow-up was compared between individuals with psychotic disorders treated with antipsychotics (n=48,162) and 1:1 matched controls without psychiatric disorders among adults without cardiometabolic diseases before or within 3 months after baseline.
Background: Depression is known to increase the risk of heart failure (HF), and physical activity could be a potential mediator of their linkage. In this study, we examined the risk of incident HF according to changes in the level of physical activity before and after the diagnosis of depression.
Methods: A South Korean National Health Insurance Sharing Service database was used.
Background: Previous studies have reported that depression can increase the risk of type 2 diabetes. However, they did not sufficiently consider antidepressants or comorbidity.
Methods: The National Health Insurance Sharing Service database was used.
Regular physical activity (PA) has been suggested as effective disease preventable strategies for Parkinson's disease (PD). Depression often precedes PD but whether PA also would reduce the risk of PD in patients with depression has not been known. The aim of study is to examine the association of regular PA with risk of PD among patients with depressive disorder.
View Article and Find Full Text PDFIntroduction: Despite the advantages of virtual reality (VR), cyber sickness makes it difficult to apply VR to those who are already anxious and in distress. Skin conductance (SC) is widely used as a bio-signal reflecting anxiety. It is positively correlated with anxiety.
View Article and Find Full Text PDFBackground And Objectives: While variabilities in metabolic parameters (METv) have been linked to adverse health outcomes in type 2 DM, their association with depression is yet to be studied. This research aimed to investigate the association between METv and depressive disorder in patients with type 2 DM.
Methods: The study involved a nationwide cohort of 1,119,631 type 2 DM patients who had undergone three or more serial health examinations between 2005 and 2012.
Article Synopsis
- The study examines the relationship between alcohol use disorders (AUDs) and comorbid mood and anxiety disorders in Korea, highlighting that many individuals face both issues simultaneously but with under-researched temporal aspects.
- Findings reveal that certain mood and anxiety disorders, such as dysthymic disorder and specific phobias, often precede alcohol dependence, indicating a potential causal relationship.
- The research suggests that understanding the timeline and interactions between these disorders is crucial for effective treatment and management strategies in affected individuals.