Comparing Medium to Long-Term Esthetic, Clinical, and Patient-Reported Outcomes Between Freehand and Computer-Assisted Dental Implant Placement: A Cross-Sectional Study.

Objective: The aim of the study was to compare medium to long-term clinical and patient-reported outcomes between implants placed with computer-assisted implant surgery (CAIS) and freehand protocols.

Materials And Methods: Thirty dental implants in the anterior maxillary region with an average of 4 years after loading were assessed by means of Pink Esthetic Scores (PESs), marginal bone level (MBL), and clinical and patient-reported outcomes.

Results: CAIS significantly outperformed freehand placement with regard to PES scores (p = 0.

Ultrasound elastography predicts anticoagulation in lower extremity deep vein thrombosis.

Objective: To investigate predictors of anticoagulation efficacy in deep venous thrombosis (DVT) by ultrasound elastography (UE).

Methods: The basic clinical, laboratory and ultrasound treatment data of fifty-eight patients with DVT were collected and analyzed. Then the results of ultrasound after 3-month anticoagulation treatment were compared among different groups.

BRCA1 Insufficiency Induces a Hypersialylated Acidic Tumor Microenvironment That Promotes Metastasis and Immunotherapy Resistance.

Unlabelled: Cancer metastasis is an extremely complex process affected by many factors. An acidic microenvironment can drive cancer cell migration toward blood vessels while also hampering immune cell activity. Here, we identified a mechanism mediated by sialyltransferases that induces an acidic tumor-permissive microenvironment (ATPME) in BRCA1-mutant and most BRCA1-low breast cancers.

Effect of prostaglandin A1 and A2 on thyrotropin secretion in rats.

The effects of prostaglandin A1 and A2 (PG A1, A2) on secretion of thyrotropin (TSH) in vivo and in vitro were studied. Hundred micrograms per kg of PG A1 and A2 were injected i. v.

Stimulatory effect of PMRPamide (Phe-Met-Arg-Phe-NH2) on thyrotropin secretion in rats.

The effect of PMRPamide (Phe-Met-Arg-Phe-NH2) on thyrotropin (TSH) and thyrotropin-releasing hormone (TRH) secretion in rats was studied. PMRPamide (600 micrograms/kg) was injected i.v.