Photosynthesis of hydrogen peroxide from earth-abundant water and air over organo-based semiconducting materials is a promising alternative to the traditional anthraquinone (AQ) method. However, the generally hydrophobic nature of organic semiconductors has led to their poor dispersibilities in aqueous systems, which built huge barriers for photon capture and reactant contact in water-based photocatalysis. Aiming at this issue, this study reports the facile synthesis of AQ-based porous aromatic frameworks (AQ-PAFs) by coupling of AQ fragments with thiophene-derived linkers via robust carbon-carbon bonds.
View Article and Find Full Text PDFIn the present study, corn starch was modified to create temperature-responsive particles, which were employed as an emulsifier to formulate Pickering emulsions (PE) for the encapsulation of compound essential oils (CEO). The temperature responsiveness of CEOPE endows PE with the characteristics of faster release rate at lower temperature and more stability at room temperature, aligning with the typical low-temperature storage conditions of fresh noodles. The characteristics of CEOPE with different oil-water ratios were analyzed by morphology, particle size, PDI, zeta-potential, FTIR and rheological measurements.
View Article and Find Full Text PDFThis study investigates the distinctly different dynamics of atomic carbon and oxygen diffusion, both on the surface and into the bulk of iron multilayer films with face-centered cubic (FCC) (100) and body-centered cubic (BCC) (110) structures, and how these processes impact the recombination behavior of carbon and oxygen, particularly at elevated temperatures. On FCC-iron (γ-iron), CO dissociation occurs around 300 K, leading to the formation of segregated carbide and oxide islands on the surface upon annealing. Above the onset temperature of 600 K, mobile oxygen atoms diffuse to the edge of the carbide islands, where they combine with carbon to form CO.
View Article and Find Full Text PDFCrop production faces persistent threats from insect-vector-borne viral diseases. Recent advancements have revealed the intricate immune mechanisms that plants deploy against viral pathogens. However, the molecular mechanisms through which plant hosts recognize viral infections and initiate antiviral defence at disease onset have not been elucidated.
View Article and Find Full Text PDFCurrently, standard protocols for body imaging and corresponding image processing pipelines in population-based cohort studies are unavailable, limiting the applications of body imaging. Based on the China Phenobank Project (CHPP), the present study described a body imaging protocol for multiple organs, including cardiac structures, liver, spleen, pancreas, kidneys, lung, prostate, and uterus, and the corresponding image processing pipelines promoted its development. Briefly, the body imaging protocol comprised a 40-min cardiac magnetic resonance imaging (MRI) scan, a 5-min computed tomography (CT) scan, a 20-min abdominal MRI scan, and a 10-min pelvic MRI scan.
View Article and Find Full Text PDFGlaucoma is an irreversible blinding eye disease characterized by apoptosis of mature neurons-retinal ganglion cells (RGCs), visual field defect and vision loss. Regeneration of RGCs and reconstruction of the neural connections between the retina and the brain is considered an effective strategy to promote visual restoration in patients with glaucoma. However, there are currently no effective methods for regenerating RGCs to restore vision in clinical practice.
View Article and Find Full Text PDFObjective: To systematically evaluate the efficacy of electrical stimulation (ES) in the treatment of patients with foot drop (FD) after stroke, and to compare the efficacy of different types of ES.
Data Sources: We searched 5 English database (PubMed, Web of Science, Embase, Cochrane Library and Scopus) and 4 Chinese databases (China National Knowledge Infrastructure (CNKI), SinoMed (CBM), VIP and Wanfang Data) from inception to June, 2024.
Data Synthesis: Traditional meta-analysis and network meta-analysis were performed using RevMan5.
Bacterial prostatitis represents a specific form of prostatitis, primarily resulting from bacterial infection and significantly impairing the life quality of patients. In this paper, we respond to the inability of conventional drugs to simultaneously address both bacterial infection and oxidative stress in the treatment of prostatitis by designing a multifunctional nanoparticle, called QM (Cu) NPs, with dual functionality. QM (Cu) NPs have the capacity to generate reactive oxygen radicals to eradicate bacteria under the influence of laser irradiation.
View Article and Find Full Text PDFJ Toxicol Environ Health A
March 2025
Parkinson's Disease (PD) a progressive neurodegenerative disorder is attributed to dopaminergic neuronal cell loss in the mid-brain substantia nigra pars compacta. A major risk factors associated with PD development is presence of excess oxidative stress. Previously, glycosides derived from were reported to play a key role in counteracting PD; however, the underlying mechanisms remain to be determined.
View Article and Find Full Text PDFBackground: Tumour-infiltrating lymphocytes (TILs) are strongly correlated with the prognosis and immunotherapy response in bladder cancer. The TIL status is typically assessed through microscopy as part of tissue pathology. Here, the authors developed Rad-TIL model, a novel radiomics model, to predict TIL status in patients with bladder cancer.
View Article and Find Full Text PDFElectrochemical nitrate reduction reaction (NORR) offers a promising alternative for ammonia production using electricity generated from renewable energy sources. Active electrocatalysts with high selectivity and high yield are required to selectively catalyze NORR to ammonia. Here, P-doped CuNi alloy thin films are electrodeposited from a deep eutectic solvent of choline chloride-ethylene glycol (ChCl/EG).
View Article and Find Full Text PDFProtein N-phosphorylation, especially in mammals, was gradually studied and attracted widespread attention. However, the lack of effective enrichment methods resulted from the intrinsic lability of the P-N bond under acidic conditions, which seriously hindered biological function elucidation. In this work, hydrophilic two-dimensional nanocomposites with enhanced hydrophilicity and coordination interaction with phosphate were designed as the HILIC stationary phase, and then the HILIC-based strategy was developed for enrichment of N-phosphopeptides under neutral conditions.
View Article and Find Full Text PDFMRGPRX2 antagonists possess the potential for the treatment of allergic rhinitis, atopic dermatitis, and chronic urticaria. Previously, we identified a class of diaryl urea (DPU) MRGPRX2 antagonists with sub-micromolar IC values . However, the structure-activity relationship remains unclear.
View Article and Find Full Text PDFJ Natl Cancer Cent
February 2025
[This corrects the article DOI: 10.1016/j.jncc.
View Article and Find Full Text PDFAPS (antiphospholipid syndrome) is an autoimmune disease characterized by thrombosis, pregnancy complications and persistent elevation of aPLs (antiphospholipid antibodies). Dysfunction of innate immune cells, ECs (endothelial cells), platelets and trophoblast cells are central to the development of APS. The UPS (ubiquitin-proteasome system) is a highly conserved post-translational modification in eukaryotes.
View Article and Find Full Text PDFBackground: Glycogen storage disease (GSD) is an inherited metabolic disorder affecting glycogen metabolism. The overall incidence of GSD is estimated to be 1 in every 20,000 to 43,000 newborns. GSD is classified into 12 types based on the enzyme deficiency and the tissues affected.
View Article and Find Full Text PDFIEEE J Biomed Health Inform
January 2025
Robust decoding performance is essential for the practical deployment of brain-computer interface (BCI) systems. Existing EEG decoding models often rely on large amounts of annotated data collected through specific experimental setups, which fail to address the heterogeneity of data distributions across different domains. This limitation hinders BCI systems from effectively managing the complexity and variability of real-world data.
View Article and Find Full Text PDFIEEE Trans Pattern Anal Mach Intell
January 2025
Estimating the 3DoF rotation from a single RGB image is an important yet challenging problem. As a popular approach, probabilistic rotation modeling additionally carries prediction uncertainty information, compared to single-prediction rotation regression. For modeling probabilistic distribution over , it is natural to use Gaussian-like Bingham distribution and matrix Fisher, however they are shown to be sensitive to outlier predictions, e.
View Article and Find Full Text PDFGoose circovirus (GoCV) is a recently identified pathogen in geese that is known to cause slow growth, feather disorder syndrome, and immunosuppression. Infection with GoCV may increase the risk of coinfections with multiple pathogens, leading to significant economic losses in the goose industry. However, due to a lack of serological detection methods, analysis of viral nucleic acids has been widely used in GoCV epidemiological surveys, which has limited accurate monitoring of the prevalence of GoCV.
View Article and Find Full Text PDFBackground: This study aimed to compare the pain reduction effects of ethnic medicinal plant extracts and nonsteroidal anti-inflammatory drugs (NSAIDs) in women with primary dysmenorrhea.
Methods: The following databases were searched: CNKI, Wanfang Data Knowledge Service Platform (Wanfang), VIP Chinese Journal Service Platform (VIP), SinoMed, PubMed, and Web of Science. The retrieval period was from the time of database construction to December 2023.
Background: Depression has been linked to disruptions in resting-state networks (RSNs). However, inconsistent findings on RSN disruptions, with variations in reported connectivity within and between RSNs, complicate the understanding of the neurobiological mechanisms underlying depression.
Methods: A systematic literature search of PubMed and Web of Science identified studies that employed resting-state functional magnetic resonance imaging (fMRI) to explore RSN changes in depression.
Background: To evaluate the potential clinical value of cerebrospinal fluid (CSF) circulating tumor DNA (ctDNA) in the diagnosis and monitors the central nervous system (CNS) lymphomas.
Methods: This was a prospective study of 17 consecutive patients with B-cell lymphoma: 10 patients with CNS lymphomas and 7 patients with B-cell lymphomas at high clinical risk of CNS relapse. Genomic profiles were performed on the CSF and plasma samples of patients by next-generation sequencing.
Consumer decision-making varies according to an individual's relationship with the recipient of the gift. This study used a mock purchase task to investigate consumer decision-making and its underlying neurological mechanisms when purchasing gifts of different prices for recipients with varying levels of intimacy. Functional near-infrared spectroscopy was used to record neural activity during the task.
View Article and Find Full Text PDFTo enhance the speed-control performance of a permanent magnet synchronous motor (PMSM) drive system, an improved sliding-mode anti-interference control strategy is presented. Firstly, to tackle the speed fluctuation issue caused by cogging torque (a periodic disturbance) and time-varying disturbances at low set speeds in PMSM, an improved sliding-mode control (ISMC) is proposed. It consists of a continuous adaptive fast terminal sliding-mode surface (CAFTSMS) and a new reaching law (NRL).
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