Effect of Larval Ages and Honey Treatment on the Sex Reversal of Betta Fish ().

<b>Background and Objective:</b> Betta fish is one of the most popular ornamental fish because of their attractive body shape, especially for males. The fish development usually results in a similar number of males and females or an even higher number of females. This study aimed to determine the effect of various concentrations of honey and the age of larvae on the sex ratio of Betta fish.

Work Participation of Hematological Cancer Survivors After Hematopoietic Cell Transplantation: A Scoping Review.

Purpose: Hematopoietic cell transplantation (HCT) is a common treatment for people diagnosed with hematological cancers. However, it can cause side effects that may affect work participation. This scoping review aims to provide an overview of the factors that influence the work participation of hematological cancer survivors who have undergone HCT.

Photoacoustic polydopamine-indocyanine green (PDA-ICG) nanoprobe for detection of senescent cells.

Cellular senescence is considered an important tumour suppression mechanism in response to damage and oncogenic stress in early lesions. However, when senescent cells are not immune-cleared and persist in the tumour microenvironment, they can drive a variety of tumour-promoting activities, including cancer initiation, progression, and metastasis. Additionally, there is compelling evidence demonstrating a direct connection between chemo(radio)therapy-induced senescence and the development of drug resistance and cancer recurrence.

Engineering of Novel Analogues That Are More Receptor-Selective and Potent than the Native Hormone, Insulin-like Peptide 5 (INSL5).

Insulin-like peptide 5 (INSL5) targets the G protein-coupled receptor, relaxin family peptide receptor 4 (RXFP4), predominantly coexpressed in the colorectum. While INSL5 also binds to the related receptor RXFP3, it does not activate it. The INSL5/RXFP4 axis is a promising target for treating gastrointestinal disorders such as constipation.

Measurement of Pancreatic Stone Protein Compared with C-Reactive Protein and Procalcitonin in the Diagnosis of Sepsis in an Intensive Care Unit: A Systematic Review.

Sepsis remains a significant challenge in the intensive care unit (ICU), with prompt diagnosis and management being critical to improving patient outcomes. Biomarkers have emerged as valuable tools for identifying and predicting sepsis outcomes, with pancreatic stone protein (PSP), procalcitonin (PCT) and C-reactive protein (CRP) as three promising candidates. This systematic review aimed to analyse and compare the diagnostic accuracy of PSP, PCT and CRP regarding sepsis in the ICU.

Hybrid immunity augments cross-variant protection against COVID-19 among immunocompromised individuals.

Background: Immunity to SARS-CoV-2 vaccination and infection differs considerably among individuals. We investigate the critical pathways that influence vaccine-induced cross-variant serological immunity among individuals at high-risk of COVID-19 complications.

Methods: Neutralizing antibodies to the wild-type SARS-CoV-2 virus and its variants (Beta, Gamma, Delta and Omicron) were analyzed in patients with autoimmune diseases, chronic comorbidities (multimorbidity), and healthy controls.

Protocol for establishing spontaneous metastasis in mice using a subcutaneous tumor model.

Recapitulating spontaneous metastasis in preclinical models is crucial for understanding mechanisms underlying cancer progression and testing effective therapeutic interventions. We present a protocol for establishing and characterizing the spontaneous metastasis model in mice. We describe steps for generating primary tumors, tumor resection, monitoring metastatic dissemination, and evaluating metastatic burden using histological and imaging techniques.

New model of sports tourism with sustainable tourism development to increase tourist arrivals in Central Aceh Regency, Indonesia.

Introduction: This study explores the development and implementation of a new sports tourism product called "Run H2O Ride" as a strategy for sustainable tourism in Indonesia.

Methods: The research employs a research and development (R&D) methodology, focusing on identifying potential issues, conducting literature reviews, designing the product, validating the design, and undergoing product development. A combination of discussion group forums (FGD) and expert judgment decisions was used to design the new sport tourism model.

Early Experience of Left Bundle Branch Pacing with Lumenless Lead in a Single Center: A Case Series.

Left bundle branch pacing (LBBP) has been subject to increasing interest over the last few years due to its capacity for physiological conduction and its advantages compared to His bundle pacing. His bundle pacing has certain limitations, such as a small pacing area for the His bundle, a high threshold that leads to battery depletion, a low R-wave amplitude that may result in atrial or His oversensing, and ventricular signal undersensing. In this case series, four patients (two female and two male) aged 62.

Unveiling the Influence of Osmotic Pretreatment on Dried Fruit Characteristics: A Meta-Analysis Approach.

Considering the diverse findings regarding the impact of osmotic pretreatment on the quality of dried products, it is important to determine whether osmotic pretreatment can either maintain or reduce the quality of fruit products. Thus, the present study aimed to scrutinize research regarding the influence of osmotic pretreatment on the qualities of dried fruits through meta-analysis. The Scopus database was used to search for relevant articles.

Effect of mobile app-based oral hygiene instructions on clinical parameters, oral bacterial diversity, and composition of subgingival microbiota in periodontitis patients.

Introduction: Oral hygiene instruction (OHI) is essential during periodontitis treatment. Various OHI approaches have been explored, including mobile apps.

Objective: To evaluate the mobile app-based OHI's effect on periodontitis management by analyzing clinical parameters and subgingival microbiota.

Past and future land use change dynamics: assessing the impact of urban development on agricultural land in the Pantura Jabar region, Indonesia.

The conversion of large-scale agricultural land into urban areas poses a significant challenge to achieving national and global food security targets, as outlined in Sustainable Development Goal number 2, which aims to eradicate hunger. Indonesia has experienced a significant decline in rice field areas, with a reduction of approximately 650 thousand hectares within a year (2017-2018), the largest being in Java. Hence, this study aims to examine the impact of urban expansion on agricultural land in the north coast region of West Java Province from 2013 to 2020 and develop a predictive model for 2030 to support sustainable land use planning.

Metaphyseal trauma of the lower extremities in major orthopedic surgery as an independent risk factor for deep vein thrombosis.

Purpose: Major orthopedic surgeries of the lower extremities, which heavily injure the metaphyseal region, are strongly associated with the risk of developing deep vein thrombosis (DVT). This study aims to investigate the role of metaphyseal trauma as an independent risk factor for DVT.

Methods: Patients undergoing major orthopedic surgery of the hip and knee had their existing DVT risk factors recorded.

Impact of Climate on Soil Organic Matter Composition in Soils of Tropical Volcanic Regions Revealed by EGA-MS and Py-GC/MS.

Soil organic matter (SOM) crucially influences the global carbon cycle, yet its molecular composition and determinants are understudied, especially for tropical volcanic regions. We investigated how SOM compounds change in response to climate, vegetation, soil horizon, and soil properties and the relationship between SOM composition and microbial decomposability in Tanzanian and Indonesian volcanic regions. We collected topsoil (0-15 cm) and subsoil (20-40 cm) horizons ( = 22; pH: 4.

Validity of the Active Australia Survey in an Australian cardiac rehabilitation population.

Objectives: To examine the long-term validity of the Active Australia Survey in a cardiac rehabilitation population using accelerometry as the reference measure.

Design: Cohort validation study.

Methods: Cardiac rehabilitation participants with coronary heart disease were recruited to a prospective cohort study.

Parasitic pygopagus conjoined twins' incidental findings in the obstructed labor of an intrapartum dead baby that had undergone emergency C-section: rare case report in South Papua.

Background: Conjoined twins (CT), which used to be historically defined as "monstrous human" and previously so-called Siamese twins in the early eighteenth century, are one of the very rare congenital malformations with an uncertain etiology and complex yet remain inconclusively debatable regarding its pathophysiological mechanisms of fusion and fission theories. Among all types of CT, parasitic CT, especially the pygopagus sub-type, is exceedingly rarer. To the best of the authors' knowledge, no parasitic CT had been reported in Papua, and this is the first finding in South Papua.

Atypical twin-to-twin transfusion syndrome case managed in a single centre in Indonesia with fetoscopic laser photocoagulation and amniopatch: 'Case Report'.

Introduction And Importance: The diagnostic criteria for Quintero staging in twin-to-twin transfusion syndrome (TTTS) are not applicable in all cases of TTTS, such as those in which the symptoms overlap with other monochorionic twin complications such as selective intrauterine growth restriction (sIUGR).

Case Presentation: A 25-year-old woman, G1P0A0, at 22-24 weeks' gestational age was diagnosed with TTTS, with no outstanding history of medication use during pregnancy, and no family history of genetic disorder or twin pregnancy. In the donor twin, persistently absent end-diastolic flow in the umbilical artery was observed using Doppler velocimetry.

Developing insulin-like peptide 5-based antagonists for the G protein-coupled receptor, RXFP4.

Human insulin-like peptide 5 (INSL5) is a gut hormone produced by colonic L-cells, and its biological functions are mediated by Relaxin Family Peptide Receptor 4 (RXFP4). Our preliminary data indicated that RXFP4 agonists are potential drug leads for the treatment of constipation. More recently, we designed and developed a novel RXFP4 antagonist, A13-nR that was shown to block agonist-induced activity in cells and animal models.

Thermal Properties' Enhancement of PLA-Starch-Based Polymer Composite Using Sucrose.

Polylactic-acid-starch-based polymer composite (PLA/TPS) has good thermal stability for biocomposites. However, the physical and mechanical properties of PLA/TPS do not meet the standards. It needed additives to enhance its physical and mechanical properties.