Publications by authors named "Harsha"

Host-seeking behavior of Culicoides species was examined from 2018 to 2019 in West Bengal, India, which elucidated diel activity, feeding success, attack rate, biting rate, and preferential landing of adult Culicoides on the cattle. A comparative assessment was done between the light trap and the aspirator. The host-seeking experiment involved a substantial timeframe of 297 h of catch collections over 27 nights.

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Background: This study aims to evaluate the long-term efficacy, safety, nutritional status, and resolution of obesity complications of patients following one-anastomosis gastric bypass (OAGB).

Methods: A retrospective observational study of patients who underwent OAGB in our center between January 2011 and December 2013 was performed.

Results: During the study period, 152 patients underwent OAGB procedure in our center.

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  • * A study presented 11 patients who underwent NO-TOTVET for goiter at a hospital in Kolkata between November 2022 and July 2023, showcasing successful operations performed through small oral ports without converting to open surgery.
  • * The average age of patients was 37.5 years, with surgeries taking about 139 minutes and requiring only 1.5 days of hospital stay; minor complications included two cases of seroma and one case of transient nerve
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Scientific medical manuscripts are fundamental to advancing research and enhancing patient care. With the emergence of artificial intelligence (AI), the process of composing such manuscripts has witnessed profound transformations. This review delves into the multifaceted role of AI in medical manuscript composition, analyzing its applications, benefits, drawbacks, and ethical implications.

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Introduction: This study aimed to perform a comparative analysis of stresses and displacements with incremental torque on the maxillary incisors and surrounding cortical bone using conventional metal brackets with rectangular slots and passive self-ligating brackets with square slots using finite element analysis (FEA).

Materials And Methods: An in vitro FEA study was conducted, in which a three-dimensional (3D) model of the maxilla was built using ANSYS software version 18 (ANSYS Inc., Canonsburg, PA).

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The jumping of crystals in the presence of external stimuli such as temperature, light, and mechanical forces is observed due to the release of accumulated strain in the crystal. Thermosalience in molecular crystals is generally induced by anisotropic thermal expansion accompanied by phase transformation. However, a thermosalient effect has not been observed in the same crystal at two different temperature zones caused by two distinct mechanisms.

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Crude oil toxicity to early life stage fish is commonly attributed to polycyclic aromatic hydrocarbons (PAHs). However, it remains unclear how the polar unresolved complex mixture (UCM), which constitutes the bulk of the water-soluble fraction of crude oil, contributes to crude oil toxicity. Additionally, the role of photomodification-induced toxicity in relation to the polar UCM is not well understood.

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Background: Enamel demineralization is an unavoidable adverse effect encountered with bonding brackets in orthodontic therapy. Introducing nanoparticles into the composite adhesive paste can prevent enamel demineralization. Titanium dioxide (TiO) is known to exhibit direct antimicrobial efficiency.

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Background: Stroke is a major cause of illness, death, and long-term disability and a major health concern worldwide. Experts consider insulin resistance (IR), a defining feature of the metabolic syndrome and a significant risk factor for stroke. Insulin resistance, or IR, is common among stroke patients.

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  • The study aims to evaluate the risk of congenital anomalies in newborns exposed to dolutegravir during pregnancy compared to those on other antiretroviral regimens, following some concerns about birth defects associated with dolutegravir use.
  • A systematic review and meta-analysis were conducted involving 26 studies, with 12 included in the final analysis, which showed no significant difference in congenital anomaly risks between the two groups of newborns (risk ratio of 1.10, p = 0.59).
  • Moderate heterogeneity was found among the studies (I = 47%), indicating some variation in the results, but overall, the findings suggest dolutegravir does not pose a significantly higher risk
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Introduction: Hepatocellular carcinoma (HCC) is a fatal cancer that is often diagnosed at the advanced stages which limits the available therapeutic options. The interaction of HGF with c-MET (a receptor tyrosine kinase) results in the activation of c-MET which subsequently triggers the PI3K/Akt/mTOR axis. Overexpression of c-MET in HCC tissues has been demonstrated to contribute to tumor progression and metastasis.

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Purpose: To evaluate the prevalence of vascular contact of the facial nerve in patients without hemifacial spasm or facial palsy using magnetic resonance imaging (MRI).

Material And Methods: Our radiology database was accessed to find a series of consecutive adult patients who underwent MRI of the brain during the study period, excluding those with a history of hemifacial spasm (HFS), facial palsy, traumatic brain injury, intracranial tumour, intracranial surgery, trigeminal neuro-vascular compression, brain radiation therapy, and studies with poor image quality. A total of 112 (224 sides) MRIs of the posterior fossa were independently reviewed by 2 radiologists for neurovascular contact involving the facial nerve.

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Background: Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity and mortality worldwide. However, there is a lack of comprehensive data from low- and middle-income countries (LMICs) regarding factors influencing COPD outcomes, particularly in regions where biomass exposure is prevalent.

Objective: The Factors Affecting Survival in Severe and Very Severe COPD Patients Admitted to Tertiary Centers of India (FAST) study aims to address this gap by evaluating factors impacting survival and exacerbation rates among COPD patients in LMICs like India, with a specific focus on biomass exposure, clinical phenotypes, and nutritional status in patients admitted to the Intensive Care Unit (ICU).

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For molecules and solids containing heavy elements, accurate electronic-structure calculations require accounting not only for electronic correlations but also for relativistic effects. In molecules, relativity can lead to severe changes in the ground-state description. In solids, the interplay between both correlation and relativity can change the stability of phases or it can lead to an emergence of completely new phases.

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MAPK pathway regulates the major events including cell division, cell death, migration, invasion, and angiogenesis. Small molecules that modulate the MAPK pathway have been demonstrated to impart cytotoxicity in cancer cells. Herein, the synthesis of a new isoxazolyl-urea derivative (QR-4) has been described and its effect on the growth of pancreatic cancer cells has been investigated.

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  • Carcinoma en cuirasse is a rare skin metastasis mainly linked to breast cancer in women, showing up as various skin lesions, often long after the original cancer diagnosis.
  • Diagnosis is difficult but can be confirmed through histological examination to differentiate it from other skin issues.
  • Treatment options are not clearly established because there are few reported cases, highlighted by a case of a 30-year-old woman whose breast cancer developed into carcinoma en cuirasse within 6 months.
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Numerous bioactive compounds have been reported to be produced by the members of the genus Streptomyces. During our previous studies, Streptomyces sp. strain 196 was tested for its antimicrobial activity, and bioactive compounds produced by this strain were characterized LC-MS and H NMR.

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Background: Migraine is a disabling primary headache disorder characterized by recurrent episodes of headache. Migraine not only imposes a burden on the sufferer but also imposes a burden on their family members too. A holistic approach is more essential in the management of migraine and family members should also be included in the management of migraine.

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Deregulated activation of the Wnt/β-catenin pathway is observed in many types of human malignancies including colon cancer. Abrogation of the Wnt/β-catenin pathway has been demonstrated as an effective way of inducing cancer cell death. Herein, a new isoxazolyl-urea (QR-5) was synthesized and examined its efficacy on the viability of colon cancer cell lines.

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  • - Oncology and critical care patients are at a higher risk for central line-associated bloodstream infections (CLABSIs) and thrombotic occlusions due to the use of central vascular access devices (CVADs), with CLABSIs increasing by 63% during the COVID-19 pandemic.
  • - A quality improvement project introduced 4% ethylenediaminetetraacetic acid (EDTA) as an antimicrobial locking solution, leading to a significant decrease in CLABSIs from 36 cases in 16 months to 6 cases in 6 months (a 59% reduction).
  • - Though the study showed promising results in reducing CLABSIs, it found no significant improvement in occlusions, and further research
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  • Natural orifice scarless cosmetic surgeries, made possible by advanced laparoscopic techniques, are gaining popularity, especially in thyroid procedures.
  • The trans-oral trans-vestibular endoscopic thyroidectomy (NO-TOTVET) method stands out for its excellent cosmetic results, shorter hospital stays, and fewer complications compared to other approaches.
  • This case report introduces and details the NO-TOTVET technique, enriching the surgical methods available to surgeons.
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The fully self-consistent (sc) method with an iterative solution of the Dyson equation provides a consistent approach for describing the ground and excited states without any dependence on the mean-field reference. In this work, we present a relativistic version of sc for molecules containing heavy elements using the exact two-component (X2C) Coulomb approximation. We benchmark SOC-81 data set containing closed shell heavy elements for the first ionization potential using the fully self-consistent as well as one-shot .

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